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Traditional Chinese medicine composition for treating oral lichen planus and preparation method thereof

A technology for oral lichen planus and composition, which is applied in the field of traditional Chinese medicine composition for treating oral lichen planus and its preparation field, and can solve the problems of poor curative effect, toxic and side effects and the like

Inactive Publication Date: 2015-07-29
QINGDAO STOMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The technical problem to be solved by the present invention is that there is no special therapeutic method and drug in clinic at present, and adrenal cortex hormone, immunosuppressant and retinoic acid drugs are mostly used for treatment, but the curative effect is not good, and some toxic and side effects often occur in long-term application ; Non-drug treatments, such as laser, surgery, freezing, etc. also have limitations in indications

Method used

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preparation example Construction

[0066] The preparation process of the oral buccal agent for external use of the present invention is as follows: 1000g of peppermint, 1000g of Qingdai, and 1000g of borneol are distilled and extracted by the steam method, and the extracted white crystals are pulverized, passed through a fine sieve of 120-150 mesh, and set aside; Tea 1000g, black nightshade 1000g, forsythia 1000g, angelica dahurica 1000g, dandelion 1000g, phellodendron 1000g, asparagus 1000g, add 10 times the mass of ethanol to soak for 2-3 hours, then heat and reflux extraction twice, each time 1~ For 2 hours, combine the two extracts and let stand; combine the above two extracts, recover ethanol under reduced pressure and concentrate until the concentration of the drug solution is 0.6g crude drug / mL. After suction filtration, the relative density of the filtrate is about 20°C 1.06; reduce the pressure to 0.03-0.08MPa, keep the temperature at 60-80°C, concentrate to a concentrated solution with a relative densi...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating oral lichen planus. An orally taken medicine comprises the following raw materials: 10 to 20 parts of rehmanniae vaporata, 10 to 20 parts of raspberries, 10 to 20 parts of leonurus, 10 to 20 parts of astragalus membranaceus, 10 to 20 parts of rhizoma anemarrhenae, 10 to 20 parts of semen cuscutae, 10 to 20 parts of polygala tenuifolia, 10 to 20 parts of bighead atractylodes rhizomes, 10 to 20 parts of rhizoma cyperi, 10 to 20 parts of scutellaria baicalensis, 10 to 20 parts of glossy privet fruits, 10 to 20 parts of prepared fleece flower roots, 10 to 20 parts of eclipta alba, 10 to 20 parts of medlar, 10 to 20 parts of roots of common peony, 10 to 20 parts of radix ophiopogonis, 10 to 20 parts of herba epimedii, 10 to 20 parts of radix polygonati officinalis, 10 to 20 parts of roots of straight ladybell and 10 to 20 parts of oldenlandia diffusa. An external use medicine comprises the following raw materials: 10 to 20 parts of cutch, 10 to 20 parts of nightshades, 10 to 20 parts of fructus forsythiae, 10 to 20 parts of radix angelicae, 10 to 20 parts of mints, 10 to 20 parts of indigo naturalis, 10 to 20 parts of dandelions, 10 to 20 parts of borneols, 10 to 20 parts of golden cypresses and 10 to 20 parts of oldenlandia diffusa. The pathogenesis of the oral lichen planus is complex, so that therapeutic methods are different from each other, but the effect is undesirable. The research finds that the traditional Chinese medicine composition combined with the immunological therapy is excellent in curative effect in treating the OLP (Oral Lichen Planus), so that the traditional Chinese medicine composition is worthy of popularization and application. The whole formula primarily nourishes liver and kidney and secondarily sooths liver-qi stagnation and purges fire for removing toxin, tonification and purgation are performed in combination, and yin and yang are mutually aided, so that the essential qi in kidney is full, the liver, the spleen, the heart and the lung are moistened and nourished, and the symptom of oral mucosa is improved.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating oral lichen planus and a preparation method thereof. Background technique [0002] Oral lichen planus is a common chronic oral mucocutaneous disease that is generally not contagious. The pathogenesis of the disease has not been fully clarified. Current research shows that its pathogenesis is related to mental factors (such as fatigue, anxiety, tension), immune factors, endocrine factors, infection factors, microcirculation disturbance factors, trace element deficiency and certain systemic diseases. (diabetes, infection, high blood pressure, gastrointestinal dysfunction). Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The disease persists for a long time and brings endless pain to patients. There is no clear conclusion about the eti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K36/81A61K9/12A61K9/48A61P1/02A61K31/045
Inventor 王万春杜锐高扬蒋声果
Owner QINGDAO STOMATOLOGICAL HOSPITAL
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