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Preparation method of medicine for preventing and treating infection after internal fixation of fracture in children

A drug and pediatric technology, applied in the field of medicine, can solve the problems of side reactions, low drug utilization rate, low local drug concentration for infection, etc., and achieve the effect of promoting tissue regeneration, safe and reliable effect, and promoting wound healing.

Inactive Publication Date: 2015-08-26
张希梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term systemic application of antibiotics may bring a series of side effects, and the concentration of local drugs in infection is often not high, so that the utilization rate of drugs is very low

Method used

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  • Preparation method of medicine for preventing and treating infection after internal fixation of fracture in children
  • Preparation method of medicine for preventing and treating infection after internal fixation of fracture in children

Examples

Experimental program
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Effect test

Embodiment

[0015] Example Lotion of the present invention

[0016] Weigh 50 grams of corn silk, 100 grams of rhododendron, 80 grams of platycodon, 120 grams of cicada slough, 80 grams of Chenopodium chinensis, 150 grams of sycamore white skin, 80 grams of Malan, 100 grams of Guanyin amaranth, 100 grams of sunflower root, and 120 grams of acacia skin , 50 grams of red yeast rice, 150 grams of single grass, 50 grams of southern salvia miltiorrhiza, 50 grams of chasing bone wind, 80 grams of licorice, 100 grams of radish leaves, 150 grams of isatidis root, 100 grams of Daqingye, 150 grams of cork, 50 grams of red cohosh , Bauhinia root 50 grams, white ox gall root 150 grams, honeysuckle vine 100 grams, add 80000 milliliters of water, heat and reflux for 3 hours in a flask equipped with a condenser tube, then filter to obtain filtrate 1 and filter residue 1; 2) to filter residue Add 20,000 ml of water to 1, heat in a flask equipped with a condenser for 1 hour, and filter to obtain filtrate 2...

experiment example

[0017] Experimental example Effect of the pharmaceutical composition of the present invention

[0018] 1. General information In this group, 50 children with infection after fracture internal fixation were divided into observation group (28 cases) and control group (22 cases). In the observation group, there were 21 males and 7 females, aged between 3 and 10 years old, with an average of 7.2 years old; the average infection area was (4.62±2.48) cm 2 ; The infection site was in the forearm and hand in 6 cases, 14 cases in the leg, and 8 cases in the foot. In the control group, there were 16 males and 6 females, aged between 2.5 and 9 years old, with an average of 6.8 years old; the average infection area was (4.28±1.92) cm 2 ; The infection site was in the forearm and hand in 4 cases, 12 cases in the leg, and 6 cases in the foot. All the children had no signs of fever and systemic infection. There was no significant difference in the general data of the two groups of childre...

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Abstract

The invention relates to a preparation method of a medicine composition for preventing and treating infection after internal fixation of fracture in children. The method comprises the following steps: 1) weighing 50g stigma maydis, 100g azalea, 80g platycodon grandiflorum, 120g cicada slough, 80g teucrium viscidum, 150g phoenix tree bark, 80g Indian Kalimeris herb, 100g gynura herb, 100g sunflower root, 120g silktree albizia bark, 50g red rice, 150g lysimachia candida, 50g inflorescence of broadleaf globethistle, 80g liquorice, 100g radish leaf, 150g radix isatidis, 100g folium isatidis, 150g amoorcorn tree bark, 50g astilbe chinensis, 50g Chinese redbud root, 150g inula cappa root and 100g honeysuckle stem, adding 80000ml water, heating in a flask equipped with a condensation tube for circumfluence for 3h, filtering to form filtrate 1 and filter residue 1, 2) adding 20000ml water into the filter residue 1, heating in the flask equipped with the condensation tube for 1h, filtering to form filtrate 2 and filter residue 2, and 3) merging the filtrate 1 and the filtrate 2, and cooling to the room temperature.

Description

[0001] The present invention is a divisional application of a patent with the application number 201510046473X, the application date is January 30, 2015, and the invention name is "a pharmaceutical composition for preventing and treating infection after internal fixation of fractures in children". technical field [0002] The invention relates to the field of medicine, in particular to a preparation method of a pharmaceutical composition for preventing and treating infection after internal fixation of fractures in children. Background technique [0003] Children are naturally active and energetic, like to play and jump, have poor self-control ability, insufficient ability to identify and judge danger, and are prone to accidental trauma. Wherein fracture is one of common types of accidental trauma. The bones of young children are still in the growth stage, and accidents such as running, playing, and falling can cause fractures and affect the normal development of limbs or joi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P19/08A61P31/04A61P29/00A61K35/64
Inventor 张希梅
Owner 张希梅
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