A Modeling and Simulation Method of 2D Intravascular Photoacoustic Image
A technology of photoacoustic image and simulation method, applied in the field of medical imaging, can solve the problems of cumbersome training conditions, long training time, insufficient test data, etc.
Active Publication Date: 2017-09-29
NORTH CHINA ELECTRIC POWER UNIV (BAODING)
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Problems solved by technology
However, IVPA imaging technology is not widely used at present, and the available test data is seriously insufficient
In addition, the practice of testing vascular variation is a more effective way of medical training, but it requires more training time and specialized guidance from experienced experts, and the training conditions are more cumbersome and strict
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[0035] The inventive method comprises the steps:
[0036] (1) Establish a blood vessel cross-section model:
[0037] as attached figure 1 As shown, the blood vessel cross-sectional model includes the imaging catheter (the ultrasonic transducer that receives the photoacoustic signal is located at the tip of the imaging catheter), lumen (blood), intima / media (muscle tissue), adventitia (connective tissue) and plaque block (fiber, calcium, lipid) four parts. The imaging catheter is located in the center of the model, surrounded by lumen (blood), plaque, intima / media and adventitia. This method ignores the aperture effect of the ultrasonic transducer (that is, when the ultrasonic transducer receives signals, the same phase distribution cannot be achieved at all parts of the sensing surface at the same time), it is regarded as an ideal point transducer, and its scanning trajectory is parallel In the imaging plane, a circular trajectory with a radius approaching zero. According ...
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The invention provides a two-dimensional intravascular photo-acoustic image modeling and simulation method. According to the method, a blood vessel cross section model comprising atherosclerotic plaques is established firstly, an imaging conduit is arranged at the center of the model, and the blood vessel cross section is divided into m parts in equal angles; then the process that the imaging conduit emits laser pulse along an axial direction from the center of the model at each angle is simulated, and optical Monte Carol simulation is performed on the multilayer vascular wall tissues corresponding to each angle so that a space electromagnetic absorption distribution function A(r) is obtained; then photo-acoustic signals P(t) of the multilayer vascular wall tissues are simulated according to the A(r); and finally blood vessel cross section images are obtained according to the m photo-acoustic signals. Large number of IVPA images can be obtained within a short period of time through limited hardware equipment so that data sources are provided to research and performance test of an intravascular photo-acoustic imaging algorithm and an IVPA image post-processing algorithm, an image library is provided to medical training, and beneficial reference is provided to acquisition of the IVPA images with higher quality.
Description
technical field [0001] The invention relates to a method for modeling and simulating two-dimensional intravascular photoacoustic (intravascular photoacoustic, IVPA) images, belonging to the technical field of medical imaging. Background technique [0002] Intravascular photoacoustic (IVPA) imaging is an imaging method. According to the different light absorption coefficients of atherosclerotic plaques with different components, the intensity of the acoustic signal generated after being irradiated by light and thermal expansion is also different. This effect has a great impact on blood vessels. Wall and atherosclerotic plaque imaging. It combines the higher contrast of light absorption in the excitation stage of photoacoustic signals and the higher resolution of ultrasonic detection in the emission stage of photoacoustic signals, and can obtain real-time images showing information such as plaque type and size. [0003] The difference in IVPA image content is caused by the ta...
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IPC IPC(8): G06T17/00
Inventor 孙正苑园
Owner NORTH CHINA ELECTRIC POWER UNIV (BAODING)