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Real-time adaptive dose calculation for radiation therapy

A radiation therapy system and radiation dose technology, applied in treatment, radiation therapy, X-ray/γ-ray/particle irradiation therapy, etc., can solve the problems of excessive dose of healthy tissue or insufficient dose of target area, no monitoring or calculation of actual dose, etc.

Active Publication Date: 2018-08-03
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Current technology does not monitor or calculate the actual dose delivered to the target volume, surrounding tissue, OAR during RT treatment, which means that healthy tissue may be overdosed or the target volume may be underdosed in fractionated treatments

Method used

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  • Real-time adaptive dose calculation for radiation therapy

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Embodiment Construction

[0018] refer to figure 1 , schematically illustrates an embodiment of a real-time adaptive dose calculation RT system 1 . The system comprises a real-time three-dimensional (3D) imaging unit 2, such as an ultrasound (US) imaging unit, a fluoroscopy imaging device, or the like. The real-time 3D US imaging unit generates real-time 3D US images 3 of regions of the subject's body 4 . A US image 3 of a subject's body region includes tissue to which radiation is simultaneously delivered from a radiation source such as a linear accelerator (LINAC) 6 . The US image 3 is stored in memory, which can include processor memory, computer memory, or persistent storage such as disk storage. The radiation-exposed tissue is measured relative to the projected radiation beam while the subject is positioned on the subject support 8 (eg couch or bed).

[0019] The real-time 3D US unit 2 includes one or more processors 10 , a display device 12 , and at least one input device 14 . Processor 10, d...

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Abstract

A radiation therapy system (1), comprising: an ultrasound (US) imaging unit (2), a registration unit (30), a US motion unit (44), and a real-time dose calculation engine (46). The ultrasound (US) imaging unit (2) generates baseline and real-time US images (3) of a region of a subject's body (4) including a target and one or more organs at risk (OAR). The registration unit (30) deformably registers a planning image (32) with the baseline US image (36), and maps (66) radiation absorption properties of tissue in the planning image (32) to the Baseline US images as described (36). The US motion unit (44) measures motion of the target volume and OAR during a radiation therapy treatment based on the real-time US images. The real-time dose calculation engine (46) calculates a real-time radiation dose delivered to the tissue based on the tissue radiation absorption properties mapped from the baseline or planning image to the real-time 3D US image (3).

Description

technical field [0001] The following generally relate to radiation therapy and medical imaging. It has particular application in connection with radiation therapy real-time dose calculation and three-dimensional real-time ultrasound imaging and will be described with particular reference to this application. However, it will be appreciated that the invention applies to other usage scenarios as well, and is not necessarily limited to the aforementioned applications. Background technique [0002] Radiation therapy (RT) identifies and delivers radiation to kill cancer cells in a target volume while sparing normal cells surrounding the target volume and including organs at risk (OARs). The planning process for RT plans the delivery of radiation in fractionated doses or doses over time. Fractional treatment improves the rate of destruction of cancer cells and allows recovery of normal cells. The planning process is the detailed process of determining the size, shape, direction...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/00
CPCA61N5/1048A61N5/1037A61N5/1071A61N2005/1072A61B34/30A61N5/1031A61B6/032A61B6/5247A61B8/08A61B8/4218A61B8/4444A61B8/463A61B8/483A61N5/1039A61N5/1049A61N5/1067A61N5/1077A61N2005/1058A61N2005/1074
Inventor S·巴拉特V·帕塔萨拉蒂A·K·贾殷
Owner KONINKLJIJKE PHILIPS NV
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