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Water-based external herbal plaster for treating infantile cough

A technology of children's cough and traditional Chinese medicine paste, which is applied in the field of medicine, can solve the problems of children's susceptibility to allergies, short duration of action, and low drug loading capacity, and achieve simple and easy production process, good affinity, and large drug loading capacity. Effect

Inactive Publication Date: 2015-12-09
郑州市儿童医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the above situation, in order to solve the defects of the prior art, the object of the present invention is to provide a water-based external Chinese medicine patch for treating children's cough, which can effectively solve the problem of low drug loading, short duration of action of traditional patches, and children's allergies. question

Method used

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  • Water-based external herbal plaster for treating infantile cough
  • Water-based external herbal plaster for treating infantile cough

Examples

Experimental program
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Effect test

Embodiment 1

[0009] When the present invention is implemented, it can be made from the following raw materials by weight: Fritillaria 31g, Radix 31g, Campanulaceae 31g, Peucedanum chinensis 21g, Pinellia 21g, Honeysuckle 21g, Bezoar 0.6g and Borneol 0.5g, Among them, the basil and platycodon are mixed together, add 8-15 times the weight of the basil and platycodon, ethanol with a volume concentration of 75%-95%, extract 1-2 times with a flash extractor, each time for 1-3min , filtered, and the dregs are set aside, the filtrate is combined, concentrated under reduced pressure at 50°C to a liquid extract I with a specific gravity of 1.10-1.15, and set aside; after the ethanol extraction, the mixed dregs of Baibu and Campanulaceae add 10 times the weight of dregs of water, Heat and reflux extraction at 65°C-90°C twice, each time for 2 hours, filter, combine the filtrates, concentrate under reduced pressure to an extract with a specific gravity of 1.15-1.25 at 50°C, and add ethanol with a volum...

Embodiment 2

[0012] When the present invention is actually implemented, it can also be made from the following raw materials by weight: Fritillaria 35g, Bezoar 35g, Platycodon grandiflorum 35g, Peucedanum chinensis 25g, Pinellia 25g, Flos Lonicerae 25g, Bezoar 0.7g and Borneol 0.6g , wherein, Ababa and Platycodon grandiflora are mixed together, and the volume concentration of adding 8-15 times of the weight of Ababa and Platycodon grandiflora is the ethanol of 75%-95%, extracting 1-2 times with a flash extractor, each time 1- 3min, filter, the dregs are ready for use, combine the filtrate, concentrate under reduced pressure at 50°C to liquid extract I with a specific gravity of 1.10-1.15, and set aside; add 10 times the weight of the dregs of water to the mixed dregs of Baibu and Platycodon grandiflorum after ethanol extraction , 65°C-90°C heating and refluxing extraction twice, each time for 2 hours, filtering, combining the filtrates, concentrating under reduced pressure to an extract wit...

Embodiment 3

[0015] When the present invention is implemented, it can also be made from the following raw materials by weight: Fritillaria 39g, Radix 39g, Campanulaceae 39g, Peucedanum chinensis 29g, Pinellia 29g, Honeysuckle 29g, Bezoar 0.8g and Borneol 0.8g , wherein, Ababa and Platycodon grandiflora are mixed together, and the volume concentration of adding 8-15 times of the weight of Ababa and Platycodon grandiflora is the ethanol of 75%-95%, extracting 1-2 times with a flash extractor, each time 1- 3min, filter, the dregs are ready for use, combine the filtrate, concentrate under reduced pressure at 50°C to liquid extract I with a specific gravity of 1.10-1.15, and set aside; add 10 times the weight of the dregs of water to the mixed dregs of Baibu and Platycodon grandiflorum after ethanol extraction , 65°C-90°C heating and refluxing extraction twice, each time for 2 hours, filtering, combining the filtrates, concentrating under reduced pressure to an extract with a specific gravity of...

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Abstract

The invention relates to a water-based external herbal plaster for treating infantile cough and effectively solves the problems that a traditional plaster is low in drug loading capacity and has a short acting duration and children are easily allergic to the plaster. According to the technical scheme for solving the problems, the water-based external herbal plaster is made from, by weight, 30-40g of unibract fritillary bulb, 30-40g of sessile Stemona root, 30-40g of Platycodon root, 20-30g of root of whiteflower Hogfennel, 20-30g of Pinellia tuber, 20-30g of honeysuckle, 0.6-0.8g of artificial bezoar, and 0.5-0.8g of borneol. The plaster has reasonable compatibility and clear therapeutic effect and is well affinitive to children's skin, free of allergy, high in drug loading capacity, high in water content and good for transdermal absorption of drugs, a production process is simple and easy, materials are green, and the plaster is creative among herbal plasters for treating infantile cough.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a water-based external Chinese medicinal patch for treating cough in children. Background technique [0002] Plaster is an important part of traditional medicine in my country. It has played an important role in protecting people's health in the history of civilization for thousands of years in our country. It has the advantages of convenient use, sustainable administration, and less toxic and side effects than other dosage forms. In recent years, a large number of external patches for children have appeared on the market. Because children's skin is still in the rapid growth period, the absorption of plaster drugs is faster than that of adults, and the effect is more significant. Because most of these traditional plaster bases are rubber plaster , hot-melt pressure-sensitive adhesives or fat-soluble organic macromolecular polymers. The nature of these matrices determines that they have a ...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/70A61K47/42A61P11/14A61K35/413A61K31/045
Inventor 刘蕾陈海燕张涛李婉盈
Owner 郑州市儿童医院
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