Granules for treating liver cirrhosis

A technology of granules and traditional Chinese medicine, applied in the field of granules for the treatment of liver cirrhosis, can solve the problems of poor liver cirrhosis and other problems

Inactive Publication Date: 2015-12-16
ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effect of current treatment products for liver cirrhosis is not very good, so there is an urgent need for a traditional Chinese medicine for the treatment of liver cirrhosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1: Take 20g of Liuyuehan, 25g of Dihongzi root, 18g of rat bougainvillea, 25g of Wupaoci, 18g of Poria cocos, 25g of verbena, 20g of rock berberine, 25g of bupleurum, 22g of angelica, 20g of salvia miltiorrhiza, 15g of yam, and 20g of tangerine peel . Filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate under reduced pressure to 60°C and the relative density is 1.05, add ethanol to make the volume percentage of the alcohol content reach 75%, stir, stand still, filter, and the relative density of the filtrate is 1.25 when the filtrate is concentrated under reduced pressure to 65°C, and ethanol is recovered to obtain a concentrated solution, which is spray-dried. The spray-drying conditions are: the inlet air temperature is 100°C, The air outlet temperature is 90°C, the material temperature is 70°C, the atomization pressure is 0.2 MPa, the s...

Embodiment 2

[0013] Embodiment 2: the present invention treats the clinical data of liver cirrhosis

[0014] Clinical medicine: prepare granule of the present invention by above-mentioned embodiment 1, each time 1 bag when taking, every bag 20g, every day 3 times, 30 days are a course of treatment. Clinical observation of 60 patients.

[0015] Diagnostic criteria: (1) Esophageal varices were found in endoscopy or esophageal barium swallow X-ray examination. (2) B-ultrasound shows that the liver echo is significantly enhanced, uneven, and the light spot is thick; or the liver surface is not smooth, uneven or jagged; or the diameter of the portal vein is ≥ 1.4 cm; or the spleen is enlarged, and the diameter of the splenic vein is ≥ 1.0 cm. (3) Ascites, accompanied by distended abdominal wall veins. (4) CT showed a nodular bulge on the outer edge of the liver, enlarged hepatic fissure, caudate lobe / right lobe ratio > 0.05, and splenomegaly. (5) Liver cirrhosis was diagnosed by laparoscopy ...

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses granules for treating liver cirrhosis. The granules are prepared by extracting the following traditional Chinese medicines in parts by weight: 20 parts of herb of threeflower bluebeard, 25 parts of root of ground cotoneaster, 18 parts of acanthus ilicifolius, 25 parts of rubustephrodes hance, 18 parts of tuckahoe, 25 parts of European berbena, 20 parts of root of meadowrue corydalis, 25 parts of Chinese thorowax root, 22 parts of Chinese angelica, 20 parts of danshen root, 15 parts of Chinese yam, 20 parts of tangerine peel, 15 parts of kudzuvine root, 25 parts of sweet wormwood herb, 15 parts of stringy stonecrop herb, 25 parts of radish seed, 20 parts of rehmannia root, 15 parts of codonopsis pilosula, 20 parts of figwort root, 15 parts of coptis root and 5 parts of licorice root. The granules can be used for treating the liver cirrhosis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a granule for treating liver cirrhosis. Background technique [0002] Liver cirrhosis is a common clinical chronic progressive liver disease, which is diffuse liver damage caused by long-term or repeated effects of one or more causes. In my country, most of them are post-hepatitis cirrhosis, and a small part are alcoholic cirrhosis and schistosome cirrhosis. Histopathologically, extensive liver cell necrosis, nodular regeneration of residual liver cells, connective tissue hyperplasia, and fibrous septum formation lead to structural destruction of hepatic lobules and formation of pseudolobules. The liver gradually deforms and hardens and develops into cirrhosis. In the early stage, there are no obvious symptoms due to the strong compensatory function of the liver. In the later stage, liver function damage and portal hypertension are the main manifestations, and multiple systems a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/16A61P1/16
Inventor 田丽华
Owner ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
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