Guifu Dihuang tablet

A technology of Dihuang Tablets and Guifu, which is applied in plant raw materials, pill delivery, digestive system, etc., can solve the problems of large dosage, impact on clinical application, and many impurities, so as to improve yield, save time and energy, and ensure diversity Effect

Inactive Publication Date: 2015-12-30
韩志强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Excipients: starch 10g, magnesium stearate 1.5g

[0065] Preparation:

[0066] (1) Extraction of volatile components of cinnamon and peony bark

[0067] Take the cinnamon and peony cortex of the prescribed amount, and grind them into 100 meshes respectively;

[0068] Supercritical CO2 extraction device such as figure 1 As shown, there are two extraction tanks, which are respectively extraction tank I and extraction tank II, wherein the extraction tank I and the extraction tank II are connected in parallel in the extraction pipeline, that is, the two extraction tanks share the air inlet pipe, and the extraction tank and the separation tank The connecting parts share the ventilation pipe, and the branch roads of the two extraction tanks are respectively equipped with switches 1 and 2, and the branch roads of the extraction tanks I and II are respectively equipped with pressure gauges.

[0069] Put the cinnamon into the extraction kettle II, put the Moutan cortex powde...

Embodiment 2

[0087] Excipients: starch 10g, magnesium stearate 1.5g

[0088] Preparation:

[0089] (1) Extraction of volatile components of cinnamon and peony bark

[0090] Take the cinnamon and peony cortex of the prescribed amount, and grind them into 50 meshes respectively;

[0091] Supercritical CO2 extraction device such as figure 1 As shown, there are two extraction tanks, which are respectively extraction tank I and extraction tank II, wherein the extraction tank I and the extraction tank II are connected in parallel in the extraction pipeline, that is, the two extraction tanks share the air inlet pipe, and the extraction tank and the separation tank The connected parts share the ventilation pipe, and the branch roads of the two extraction kettles are respectively equipped with switches to control the adjustment of the pressure.

[0092] Put the cinnamon into the extraction kettle II, put the moutan bark powder into the extraction tank I, turn on the switch 1 of the extraction k...

Embodiment 3

[0110] Preparation:

[0111] (1) Extraction of volatile components of cinnamon and peony bark

[0112] Take the cinnamon and peony bark of the prescribed amount, and grind them into 150 meshes respectively;

[0113] Supercritical CO2 extraction device such as figure 1 As shown, there are two extraction tanks, which are respectively extraction tank I and extraction tank II, wherein the extraction tank I and the extraction tank II are connected in parallel in the extraction pipeline, that is, the two extraction tanks share the air inlet pipe, and the extraction tank and the separation tank The connected parts share the ventilation pipe, and the branch roads of the two extraction kettles are respectively equipped with switches to control the adjustment of the pressure.

[0114] Put the cinnamon into the extraction kettle II, put the moutan bark powder into the extraction tank I, turn on the switch 1 of the extraction kettle I and the switch 2 of the extraction kettle II, adjus...

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Abstract

The invention relates to a Guifu Dihuang tablet. The preparation method of the Guifu Dihuang tablet comprises the steps that (1) supercritical CO2 extraction of volatile components of cinnamomum cassia and moutan bark is conducted; (2) continuous ethanol concentration change extraction of effective constituents of radix rehmanniae preparata, the fruits of medicinal cornel, Chinese yam and rhizoma alismatis is carried out; (3) aqueous extraction of dregs of a decoction of radix aconiti carmichaeli and the rest of drugs is performed; (4) the tablet is prepared. By the adoption of the preparation method, the Guifu Dihuang tablet which is high in effective constituent content, good in drug effect, high in bioavailability and small in side effect is obtained.

Description

Technical field: [0001] Technical field: the present invention relates to Guifu Dihuang Tablets, specifically, the present invention relates to Guifu Dihuang Tablets and a preparation method thereof. Background technique: [0002] Insufficient kidney yang, soreness and coldness of the waist and knees, edema of the limbs, difficulty in urinating or profuse urination, wheezing and coughing due to phlegm and fluid retention, and thirst are common clinical symptoms. Traditional Chinese medicine often treats them by warming and tonifying kidney yang, and the curative effect is remarkable. Guifu Dihuang Drug-like preparations are its representative drugs. [0003] In the first part of "Chinese Pharmacopoeia" in 2010, there is an introduction to the prescription and preparation method of Guifu Dihuang Wan. The prescription is: cinnamon 20g, aconite (made) 20g, rehmannia glutinosa 160g, dogwood (made) 80g, Moutan bark 60g, Yam 80g, Poria cocos 60g, Alisma 60g; the preparation metho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/20A61K47/36A61K47/38A61P1/14A61P13/12
Inventor 韩志强
Owner 韩志强
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