Lumbricus bioactive small peptide effective part composition

A technology of effective parts and compositions, applied in the field of effective parts composition of traditional Chinese medicine and its preparation field, can solve the problems of rebound spots, harmful to the body, etc., and achieve the effects of delaying aging, lowering blood pressure, and scavenging free radicals

Inactive Publication Date: 2016-01-27
ANHUI BIOLOGICAL PEPTIDE IND RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it can effectively achieve the purpose of freckle removal and whitening, long-term use is harmful to the body, and prone to rebound spots caused by lead and mercury poisoning

Method used

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  • Lumbricus bioactive small peptide effective part composition
  • Lumbricus bioactive small peptide effective part composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Prescription: take 30g of Dilong small peptide, 80g of total glycosides of paeony, 40g of total polysaccharides of Atractylodes macrocephala, and 100g of total polysaccharides of white poria cocos

[0064]Preparation method: Preparation of earthworm small peptide: take earthworm, crush it properly, add 15 times the amount of water to homogenate for 10 minutes, heat and boil for 15 minutes, let cool to room temperature, use hydrochloric acid to adjust the pH to 2.0, and then add 1% of the substrate Pepsin, hydrolyze at 40°C for 1 hour, then use sodium hydroxide solution to adjust the pH to 8.0, add trypsin with 1% substrate amount, and hydrolyze at 40°C for 3 hours, stir constantly and adjust the pH to 8.0 After the enzymolysis is completed, continue to heat up and boil for 15 minutes, let cool, centrifuge, collect the supernatant, adjust the pH to 7.0, add 1% activated carbon, stir evenly, filter, and use a hollow fiber membrane with a molecular weight cut-off of 3kD for...

Embodiment 2

[0070] Prescription: Dilong small peptide 3g, total glucosides of paeony 8g, total polysaccharides of Atractylodes macrocephala 4g, total polysaccharides of white poria cocos 10g

[0071] Preparation method: the preparation of each effective part is the same as in Example 1. Take the above-mentioned effective part, add 20g of propylene glycol, stir evenly, sprinkle 0.5g of sodium carboxymethyl cellulose, stir slightly, let it stand until it is completely dissolved, add purified water to 1000g , stir well, let stand for 24 hours, that is.

Embodiment 3

[0073] Prescription: Take 20g of Dilong small peptide, 50g of total glucosides of paeony, 20g of total polysaccharides of Atractylodes macrocephala, 60g of total polysaccharides of white poria cocos

[0074] Preparation method: the preparation of each effective part is the same as in Example 1. Take the above-mentioned effective parts, add 7.2 g of hydroxypropyl cellulose, mix well, use 50% syrup to make a soft material, granulate with a 18-mesh sieve, and dry at 70 ° C. Sieve through a 20-mesh sieve, add 1.4 g of magnesium stearate, mix well, pack into capsules, and obtain.

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses a lumbricus bioactive small peptide effective part composition. The composition is composed of small peptides extracted from lumbricus, total glucosides extracted from paeony, total polysaccharides extracted from rhizoma atractylodis and total polysaccharides extracted from white poria cocos by a certain ratio and made into various dosage forms by addition of pharmaceutical conventional accessories. The composition has functions of Qi tonifying, blood replenishing, whitening and skin moisturizing and is applicable to treatment of pachylosis, sallow complexion, chloasma, chromatosis, pimples, acnes and the like caused by deficiency-cold of Qi and blood (endocrine dyscrasia).

Description

technical field [0001] The present invention relates to a composition of effective parts of traditional Chinese medicine with freckle-removing and whitening effects and a preparation method thereof, in particular to a composition of effective parts of traditional Chinese medicine extracted from Dilong, Paeoniae Alba, Atractylodes Rhizoma Atractylodes Rhizome and Poria cocos, and a preparation method thereof, belonging to the field of traditional Chinese medicines . Background technique [0002] In modern life, due to many adverse factors such as physiological functions, external environment and indiscriminate use of cosmetics, there are many clinical manifestations, such as pregnancy spots, freckles, chloasma, sun spots, acne, acne, red blood streaks on the face , lead deposition (lead face) caused by cosmetics, and other pigmentation, this is a very common phenomenon in modern women's facial skin. Beauty is a common psychology of every woman, especially the face, but once ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01C12P21/06C07K1/34C08B37/00A61P17/00A61K31/715A61K36/71
CPCY02P20/54
Inventor 代龙卢宁柏道鸣
Owner ANHUI BIOLOGICAL PEPTIDE IND RES INST
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