Method for measuring the concentration of gas molecules in the respiratory and circulatory system in exhaled breath

A circulatory system and gas molecule technology, which is applied to the structural details of gas analyzers, measuring devices, and analyzing gas mixtures, etc. question
CN105388256BActive Publication Date: 2017-07-07SUNVOU MEDICAL ELECTRONICS
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SUNVOU MEDICAL ELECTRONICS
Publication Date
2017-07-07

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Abstract

The invention provides a measuring method for the concentration of gas molecules from a respiratory and circulatory system in expired gas to realize acquisition and analysis of nitric oxide gas in expired gas in a tidal breathing state. According to the method, when tidal breathing flow is greater than 150 ml / s and airway retention time is less than 1 s, changes of the concentration of CO2 in the expired gas are monitored by using a CO2 monitoring module; the concentration Ce of the expired gas X at different time points is measured; according to the breathing state displayed by a CO2 curve, the concentration Ce at at least two time points, i.e., Ce(t1) and Ce(t2), when the expired gas X is in an alveolar area is selected; since the contribution of Caw in an airway area can be neglected during high flow, Ce(t) is approximately equal to Calv(t); thus, the concentration Ca of X in the alveolar area and the concentration Cw of X entering alveoli after circulation can be calculated according to the equation that Calv(t) = Ca + kCw.
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Description

technical field

[0001] The invention relates to a method for measuring the concentration of gas molecules in exhaled air. Background technique

[0002] It is known that the measurement of various gas molecular components and their concentrations in the exhaled air of the human body can assist doctors in diagnosing patients' diseases, monitoring disease states and observing treatment effects, etc. The source of a certain gas molecule X in the breath is mainly the sum of the gas X1 produced and exhaled by the respiratory system and the gas X2 produced by other systems and passed to the respiratory system through the circulatory system and exhaled. The respiratory system can be subdivided into airway and alveolar parts, so X can be subdivided into airway produced and exhaled gas X11, alveolar produced and exhaled gas X12, and other systems produce gas that is delivered to the alveoli through the circulatory system sum of x2.

[0003] CASE1: For some gas molecules X, such as C...

Claims

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