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Drug for treating gynecological pruritus vulvae and vaginitis and extraction technology thereof

A technology for genital itching and vaginitis, which is applied in directions such as drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve the problems of difficulty in identifying the active ingredients and content of medicinal materials, destroying the nature of traditional Chinese medicinal materials, and destroying active ingredients, and achieves easy detection and good color. , the effect of dose reduction

Inactive Publication Date: 2016-03-23
杨丽敏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But the extraction method of Chinese medicine compound preparation has the following deficiencies at present, (1) multiple Chinese medicinal materials are mixed and extracted simultaneously, destroying the original nature of Chinese medicinal materials, and it is difficult to identify the active ingredients and content of medicinal materials; (2) some substances are heated quickly If it is destroyed, an irreversible reaction occurs, and it becomes a colloid, which is difficult to dissolve and can only be dissolved with organic matter; (3) From the surface, the medicinal materials extracted by the existing process have poor color, low degree of hydrolysis, low activity, and large dosage , the effect is not obvious, the yield is low
[0005] And the applicant's Inner Mongolia Medical College in 2008 application number is 200810145230.1 patent application "medicine for the treatment of gynecological vulva itching and vaginitis", the process method it adopts is to carry out alcohol extraction and water extraction by high temperature, so it is easy to make the water extract The active ingredients are destroyed in large quantities, which reduces the activity of the drug

Method used

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  • Drug for treating gynecological pruritus vulvae and vaginitis and extraction technology thereof

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Experimental program
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Effect test

Embodiment 1

[0019] Embodiment 1: A kind of extraction process of the medicine of treating gynecological vulva pruritus and vaginitis, it is finished by following steps, (1) medicinal material is pulverized; (2) medicinal material is extracted with water once; (3) dregs of medicinal material is extracted with water twice. water extraction dry powder; (4) primary alcohol extraction of medicinal residues; (5) alcohol extraction dry powder obtained after secondary alcohol extraction of medicinal residues; (6) preparation of medicinal material extracts; wherein,

[0020] (1) Crushing of medicinal materials: select medicinal materials Sophora flavescens, Gardenia, Folium Folium, Dandelion, Forsythia, Coptidis, Salvia, Scutellaria, Cortex Phellodendron, Yin Chen, Rhubarb, Trichosanthes and Cnidium, and grind the above-mentioned Chinese medicinal materials into powder ;

[0021] (2) Carry out water extraction for each crushed medicinal material: Soak the crushed medicinal materials in pure water ...

Embodiment 2

[0027] Embodiment 2: A kind of extraction process of the medicine of treating gynecological vulva pruritus and vaginitis, it is finished by following steps, (1) medicinal material is pulverized; (2) medicinal material is extracted by water once; (3) dregs of medicinal material is extracted by water twice. water extraction dry powder; (4) primary alcohol extraction of medicinal residues; (5) alcohol extraction dry powder obtained after secondary alcohol extraction of medicinal residues; (6) preparation of medicinal material extracts; wherein,

[0028](1) Crushing of medicinal materials: select medicinal materials Sophora flavescens, Gardenia, Folium Folium, Dandelion, Forsythia, Coptidis, Salvia, Scutellaria, Cortex Phellodendron, Yin Chen, Rhubarb, Trichosanthes and Cnidium, and grind the above-mentioned Chinese medicinal materials into powder ;

[0029] (2) Carry out water extraction for each crushed medicinal material: Soak the crushed medicinal materials in pure water at 15...

Embodiment 3

[0035] Embodiment 3: a kind of extraction process of the medicine of treating gynecological vulva pruritus and vaginitis, it is finished by following steps, (1) medicinal material is pulverized; (2) medicinal material is extracted by water once; (3) dregs of medicinal material is extracted by water twice. water extraction dry powder; (4) primary alcohol extraction of medicinal residues; (5) alcohol extraction dry powder obtained after secondary alcohol extraction of medicinal residues; (6) preparation of medicinal material extracts; wherein,

[0036] (1) Crushing of medicinal materials: select medicinal materials Sophora flavescens, Gardenia, Folium Folium, Dandelion, Forsythia, Coptidis, Salvia, Scutellaria, Cortex Phellodendron, Yin Chen, Rhubarb, Trichosanthes and Cnidium, and grind the above-mentioned Chinese medicinal materials into powder ;

[0037] (2) Carry out water extraction for each crushed medicinal material: Soak the crushed medicinal materials in pure water for ...

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Abstract

The invention discloses a drug for treating gynecological pruritus vulvae and vaginitis and an extraction technology thereof. The extraction technology comprises the following steps that 1, medicinal materials are smashed; 2, first-time water extraction of the medicinal materials is conducted; 3, second-time water extraction of drug dregs is conducted to prepare water extraction dry powder; 4, first-time alcohol extraction of the drug dregs is conducted; 5, second-time alcohol extraction of the drug dregs is conducted to prepare alcohol extraction dry powder; 6, medicinal material extract is prepared. The drug for treating the gynecological pruritus vulvae and vaginitis and the extraction technology thereof have the advantages that native natures of the traditional Chinese medicinal materials can be guaranteed, and the effective components and content of the medicinal materials are well identified; drug dosage is increased or decreased according to extracted components and the compatibility need, and the method is flexible, convenient and scientific; the medicinal materials extracted through freeze drying are good in color by being judged by appearance and good in degree of hydrolysis and activity, drug dosage is less, the effect is good, and the yield is large; industrial production is easy to carry out, the raw materials are not wasted, and one drug can be used for multiple purposes; when the drug is stored separately, the drug is good in stability, easy to store and convenient to use; all the drugs are extracted separately, and detection is convenient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine and its extraction process, in particular to a medicine for treating gynecological vulvar itching and vaginitis and its extraction process. Background technique [0002] Vaginitis is an inflammation of the vaginal mucosa and submucosal connective tissue, and is a common disease in gynecological clinics. Clinically, vaginitis is characterized by changes in the characteristics of leucorrhea and vulvar itching and burning pain. Dyspareunia is also common. When the infection involves the urethra, there may be symptoms such as dysuria and urgency. Common vaginitis includes bacterial vaginosis, trichomonas vaginitis, fungal vaginitis, and senile vaginitis. Garder et al. studied 1181 cases of vaginitis and found that 41% were bacterial, 27% were fungal, and 24% were trichomonas. Senile vaginitis occurs after menopause, oophorectomy or pelvic radiation therapy, and its incidence is reported to be as hig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P15/02
Inventor 杨丽敏欧阳晓辉李睿亚
Owner 杨丽敏
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