Lactoferrin and brain health and development in infants and young children

A lactoferrin, brain development technology, applied in the fields of brain protection, brain development, and brain health, can solve problems such as delayed cognitive function establishment

Active Publication Date: 2018-12-14
SOC DES PROD NESTLE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, this can lead to a delay in the establishment of cognitive functions (ability to learn, focus, etc.)

Method used

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  • Lactoferrin and brain health and development in infants and young children
  • Lactoferrin and brain health and development in infants and young children
  • Lactoferrin and brain health and development in infants and young children

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Experimental program
Comparison scheme
Effect test

Embodiment

[0111] Bioactivity of lactoferrin-rich bovine milk fraction contributes to neuronal cell survival and axonal outgrowth in vitro.

[0112] The process of axon outgrowth involves the outgrowth of axons from neurons as part of neuronal development. The effect of lactoferrin-enriched bovine milk fractions on axonal outgrowth was determined using a well-established and commonly used in vitro bioassay.

[0113] Briefly, NS20Y murine neuroblastoma cells (DSMZ) from cryogenic storage were thawed at approximately 27 × 10 3 cells / cm 2 Density of ® was plated in tissue culture treated flasks (Falcon) and expanded in the presence of DMEM (Gibco) containing 10% FCS (Gibco) and 2mM L-glutamine (Gibco). Two days after plating, the cells were detached from the flasks by mechanical agitation (tapping the flask) and a single cell suspension was obtained by passing the suspension several times through a flame-polished glass pipette. Cells were then plated on 13 mm round glass coverslips at a ...

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PUM

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Abstract

In general, the present invention relates to the field of brain development and brain health. One embodiment of the present invention relates to compositions useful for the treatment or prevention of delayed brain development and / or delayed development of the nervous system. Cognitive performance may also be improved.

Description

[0001] This application is a branch of Chinese Patent Application No. 201080031300.6 with an application date of May 7, 2010, a priority date of May 12, 2009, and an invention titled "Lactoferrin and Brain Health and Development of Infants and Young Children" Application. technical field [0002] In general, the present invention relates to the fields of brain health, brain protection and brain development. One embodiment of the present invention relates to compositions useful for the treatment or prevention of delayed brain development and / or delayed development of the nervous system. Can protect neuron cells in the brain. Cognitive performance may also be improved. Background technique [0003] Breast milk is recommended for all infants and young children. However, in some cases, breastfeeding is insufficient or unsuccessful or is not advised for medical reasons, or the mother chooses not to breastfeed at all or for periods of several weeks or more. For these situation...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/40A61P25/28A23L33/00A23L33/19A23J1/20A23C19/05A23C9/152A23C23/00
CPCA23C9/1526A23C19/053A23J1/205A61K35/20A61K38/40A23V2002/00A23V2200/322A23V2250/54248A23L33/40A23L33/19A61P25/00A61P25/28A61P27/02A61P43/00
Inventor B·王M·福雷J·施密特
Owner SOC DES PROD NESTLE SA
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