Traditional Chinese medicine uterine perfusion solution for treating bovine ovarian cyst and preparation method thereof

An ovarian cyst and perfusate technology, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, can solve problems such as harm to human health, hormones are not allowed to be used by dairy animals, and the economic benefits of dairy farms are affected. To achieve the effect of improving the extraction rate

Active Publication Date: 2020-06-02
INNER MONGOLIA AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although cows suffering from bovine ovarian cysts will partly heal themselves with changes in their own constitution, the self-healing rate is only about 20%; if the sick cows are not treated and treated in time, it will seriously affect the breeding production and reduce the productivity of the pasture. Reproductive rate, prolonging the calving interval of dairy cows, affecting the economic benefits of dairy farms and reducing breeding efficiency, so it is necessary to detect and treat bovine ovarian cysts as early as possible
[0004] At present, hormone therapy or surgery is generally used to treat bovine ovarian cysts, but both hormone therapy and surgical methods have certain defects in the treatment of bovine ovarian cysts: 1. my country has strict restrictions on the use of hormones in cattle farms, and the use of hormones will cause emulsions Hormone residues in the medium affect the quality of dairy products and endanger human health, especially for infants and children. Many hormones are not allowed to be used in dairy animals (Guidelines for the Use of Pollution-free Food and Dairy Cattle Raising Veterinary Drugs NY5046-2001)
2. Surgical therapy includes crushing cyst and cyst puncture, etc. The cure rate of surgical therapy is poor, and it is easy to cause infection and inflammation, which will bring difficulties to future treatment and conception

Method used

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  • Traditional Chinese medicine uterine perfusion solution for treating bovine ovarian cyst and preparation method thereof
  • Traditional Chinese medicine uterine perfusion solution for treating bovine ovarian cyst and preparation method thereof
  • Traditional Chinese medicine uterine perfusion solution for treating bovine ovarian cyst and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0024] The traditional Chinese medicine uterine perfusion solution for treating bovine ovarian cysts, which includes the following raw material components: 20g Sanleng, 20g Zezhu, 40g Astragalus, 20g Codonopsis, 20g fried Radix Paeoniae Rubra, 20g Danpi, 25g Poria cocos, 15g peach kernel, Chuanduan 20g, Rhizoma Cyperi 20g, Rhizoma Chuanxiong 15g, Patrinia 20g, Angelica 20g, Coix Seed 30g, Green Bark 15g.

[0025] Its preparation method is as follows:

[0026] Step (1) Weighing: take the medicinal material according to the above weight.

[0027] Step (2) crushing: crushing the whole prescription medicinal materials to 20 orders;

[0028] Step (3) Alcohol extraction: at a temperature of 35° C., reflux extracting the medicinal material with ethanol with a mass ratio of 8 times the mass ratio of the medicinal material and a concentration of 75% for 2 hours. After the reflux extraction is completed, filter to obtain the alcohol extract. The alcohol extract adopts the distillation...

Embodiment 2

[0032] The traditional Chinese medicine uterine infusion solution for treating bovine ovarian cysts, which includes the following quality raw material components: Sanleng 30g, Curcuma 30g, Radix Astragali 60g, Ginseng 30g, Fried Radix Paeoniae Rubra 30g, Dan Cortex 30g, Poria 35g, Safflower 20g, Sichuan Broken 30g, Rhizoma Cyperi 30g, Rhizoma Chuanxiong 20g, Patrinia 30g, Angelica 30g, Coix Seed 40g, Tangerine Peel 20g.

[0033] Its preparation method is as follows:

[0034] Step (1) Weighing: take the medicinal material according to the above weight.

[0035] Step (2) crushing: crushing the whole prescription medicinal materials to 20 orders;

[0036] Step (3) Alcohol extraction: at a temperature of 36°C, use 75% ethanol, which is 8 times the mass ratio of the medicinal material, to carry out reflux extraction of the medicinal material for 2 hours. After the reflux extraction is completed, obtain the alcohol extract by filtration, The liquid extract adopts the distillation ...

Embodiment 3

[0040] The traditional Chinese medicine uterine infusion solution for treating bovine ovarian cysts, which includes the following raw material components: 35g trigonum, 35g curcuma, 110g astragalus, 60g heterophylla, 60g fried red peony root, 60g paeonol, 70g poria cocos, 40g peach kernel, Sichuan Broken 60g, Rhizoma Cyperi 60g, Rhizoma Chuanxiong 40g, Patrinia 60g, Angelica 60g, Coix Seed 80g, Qingpi 40g.

[0041] Its preparation method is as follows:

[0042] Step (1) Weighing: take the medicinal material according to the above weight.

[0043] Step (2) crushing: crushing the whole prescription medicinal materials to 20 orders;

[0044] Step (3) alcohol extraction: at a temperature of 37° C., reflux extraction of the medicinal material with ethanol with a mass ratio of 8 times the mass ratio of the medicinal material and a concentration of 75% for 2 hours. After the reflux extraction is completed, filter to obtain the alcohol extract. The alcohol extract adopts the distillat...

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Abstract

The invention discloses a traditional Chinese medicinal uterus perfusate for treating bovine ovarian cyst and a preparation method of the uterus perfusate. The uterus perfusate consists of the following medicinal raw material components: rhizoma sparganii, rhizoma curcumae, radix astragali, radix codonopsis or ginseng or radix pseudostellariae, poria cocos, peach kernel or flos carthami, rhizoma cyperi, coix seed, pericarpium citri reticulatae viride or dried orange peel; and the preparation method of the traditional Chinese medicinal uterus perfusate for treating bovine ovarian cyst comprises the following steps: (1) weighing; (2) crushing; (3) alcohol extraction; (4) water extraction; and (5) post-processing. The traditional Chinese medicinal uterus perfusate disclosed by the invention has the advantages that verified by researches and tests for years, the uterus perfusate, which is prepared from pollution-free traditional Chinese medicines, can achieve a cure rate of 60-80% on the bovine ovarian cyst; the uterus perfusate, which is free from hormones or harmful substances, is free from influence on milk or meat quality after being applied to infected cattle; and the key control point of the preparation process of the traditional Chinese medicinal uterus perfusate for treating bovine ovarian cyst is to control the temperature of the alcohol extraction at 35-38 DEG C, so that the extraction rate of major active ingredients in the medicinal materials is improved.

Description

Technical field: [0001] The invention relates to a compound traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine uterine perfusate for treating bovine ovarian cysts and a preparation method thereof. Background technique: [0002] Bovine ovarian cysts refer to the formation of cystic masses on bovine ovaries. It is generally believed that it is related to excessive secretion of follicle-stimulating hormone and insufficient secretion of luteinizing hormone. It mainly includes follicular cysts and corpus luteum cysts. Sick cattle show extreme restlessness, loud mooing, loss of appetite, ferocious temperament, and sometimes attack humans and animals. [0003] Although cows suffering from bovine ovarian cysts will partly heal themselves with changes in their own constitution, the self-healing rate is only about 20%; if the sick cows are not treated and treated in time, it will seriously affect the breeding prod...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P15/00
CPCA61K9/0034A61K36/076A61K36/185A61K36/232A61K36/236A61K36/258A61K36/286A61K36/344A61K36/36A61K36/481A61K36/65A61K36/71A61K36/736A61K36/752A61K36/8905A61K36/8994A61K36/902A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 祁生旺李云章刘俊平
Owner INNER MONGOLIA AGRICULTURAL UNIVERSITY
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