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A medicine for treating heart blood insufficient type atrial fibrillation

A technology for atrial fibrillation and heart failure, applied in the field of traditional Chinese medicine, can solve the problems of prolonging the time of cardiac repolarization and increasing the mortality of patients, and achieve the effects of improving the quality of life, reducing the frequency of attacks, and relieving symptoms

Inactive Publication Date: 2016-05-04
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the main disadvantage of the new class III AAD is still the excessive prolongation of cardiac repolarization time, especially the secondary prolongation of QT interval and torsades de pointes, which can increase the mortality of patients

Method used

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  • A medicine for treating heart blood insufficient type atrial fibrillation
  • A medicine for treating heart blood insufficient type atrial fibrillation
  • A medicine for treating heart blood insufficient type atrial fibrillation

Examples

Experimental program
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Effect test

preparation example Construction

[0031] The present invention also provides a preparation method of the above-mentioned medicinal dropping pills, which includes:

[0032] In the first step, put the above-mentioned twenty-two medicines in a decoction container, add water for the first time until the surface of the medicinal material is submerged by 10-15cm, decoc on a slow fire for 20-30 minutes, count the time after the medicine has boiled, filter, and add water again to the filter residue. Submerge the surface of the filter residue for 10-15cm, decoc on a slow fire for 20-30 minutes, filter and combine the filtrate to concentrate the extract with a relative density of 1.25 to 1.35 at 65℃;

[0033] In the second step, the extract obtained in the first step was added to the mixed matrix of molten polyethylene glycol 6000 and polyethylene glycol 4000 in a mass ratio of 1:3, kept at 80°C, and dripped into the mixture at a constant rate. In the methyl silicone oil, drain the formed drops and wipe off the coolant on th...

Embodiment 1

[0059] Example 1 Decoction liquid

[0060] Combine American ginseng 10g, Radix sage ginseng 20g, Ophiopogon japonicus 20g, Schisandra 10g, Scrophulariaceae 10g, Salvia 10g, Angelica 20g, White peony 20g, Rehmannia glutinosa 30g, Ejiao 20g, Roasted licorice 50g, Roasted ephedra 10g, Roasted aconite 10g, Fine Xin 10g, sandalwood 10g, turtle shell 30g, cinnamon sticks 10g, kudzu root 20g, raw keel 20g, raw oyster 20g, amber 10g and Fushen 20g are placed in the decoction container, and water is added for the first time until the surface of the medicinal material is submerged 15cm, slow fire Decoction for 30 minutes, count the time after the medicine has boiled, filter, add water again to the filter residue to submerge the surface of the filter residue 15cm, decoc on a slow fire for 30 minutes, count the time after the medicine has boiled, filter, and combine the filtrate to obtain the medicine solution for use.

Embodiment 2

[0061] Example 2 Pills

[0062] Combine American ginseng 10g, Radix sage ginseng 20g, Ophiopogon japonicus 20g, Schisandra 10g, Scrophulariaceae 10g, Salvia 10g, Angelica 20g, White peony 20g, Rehmannia glutinosa 30g, Ejiao 20g, Roasted licorice 50g, Roasted ephedra 10g, Roasted aconite 10g, Fine Xin 10g, sandalwood 10g, turtle shell 30g, cinnamon sticks 10g, kudzu root 20g, raw keel 20g, raw oyster 20g, amber 10g and Fushen 20g are placed in the decoction container, and water is added for the first time until the surface of the medicinal material is submerged 15cm, slow fire Decoction for 30 minutes, count the time after the medicine has boiled, filter, add water again to the filter residue to submerge the surface of the filter residue 15cm, simmer for 30 minutes, count the time after the medicine has boiled, filter, and combine the filtrate to concentrate the immersion at 1.30 at a relative density of 65℃ Paste, the obtained extract is added to the mixed matrix of molten polyet...

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Abstract

A medicine for treating heart blood insufficient type atrial fibrillation is provided. Raw material medicines of the medicine comprise American ginseng, heterophylly falsestarwort root, liriope spicata, Chinese magnolia vine fruit, figwort root, danshen root, Chinese angelica, debark peony root, prepared rehmannia root, ass hide glue, honey-fried licorice root, honey-fried herba ephedrae, prepared common monkshood branched root, manchurian wildginger, sandalwood, turtle carapace, cassia twig, kudzu vine root, raw bone fossil of big mammals, raw oyster shell, amber and Indian bread with hostwood. The medicine is determined through screening and safety evaluation of traditional Chinese medicine compound effective components, on the basis of a large quantity of clinical treatment for the heart blood insufficient type atrial fibrillation, and on the basis of proving curative effects of the medicine through in-vitro pharmacodynamics studies with animal experiment models. The medicine effectively relives symptoms when a patient is attached with the atrial fibrillation, reduces the attack frequency of the atrial fibrillation and improves quality of life of a patient, thereby deserving clinical popularization and application.

Description

Technical field [0001] The present invention relates to the technical field of traditional Chinese medicine, and in particular to a medicine for treating atrial fibrillation of hypocardiac type. Background technique [0002] The morbidity and mortality of cardiovascular diseases are increasing year by year, and it has now become the first in our country. Arrhythmia is one of the four major clinical cardiovascular diseases (ie hypertension, coronary heart disease, arrhythmia, and heart failure). It can be caused by a variety of causes. According to the rate of arrhythmia, it can be divided into three categories: 1. Tachyarrhythmia, 2. Bradyarrhythmia, 3. Tachyarrhythmia with bradyarrhythmia, including fast-slow syndrome and slow-fast syndrome. Among them, the incidence, severity, and difficulty of treatment of tachyarrhythmia are far greater than those of bradyarrhythmia. Common tachyarrhythmias can be divided into premature contractions, tachycardia, flutter and fibrillation, a...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P9/06A61K35/36A61K35/586A61K35/02A61K35/618A61K35/10
CPCA61K36/258A61K9/0095A61K9/2031A61K35/02A61K35/10A61K35/36A61K35/586A61K35/618A61K36/076A61K36/17A61K36/185A61K36/232A61K36/268A61K36/36A61K36/484A61K36/488A61K36/537A61K36/54A61K36/57A61K36/65A61K36/71A61K36/714A61K36/79A61K36/804A61K36/808A61K36/8968A61K2236/331A61K2236/39A61K2300/00
Inventor 赵玉妹
Owner QINGDAO HUAREN TECH INCUBATOR
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