Ferulic acid and phospholipid complex and application thereof to preparation of skin-whitening cosmetics

Abstract

The invention discloses a ferulic acid and phospholipid complex and application thereof to preparation of skin-whitening cosmetics. The ferulic acid and phospholipid complex is obtained after ferulic acid and phospholipid are heated, stirred and compounded in a non-protonic solvent and the non-protonic solvent is removed. The invention also provides the skin-whitening cosmetics containing the ferulic acid and phospholipid complex. The cosmetics include skin oil, emulsion and cream with the skin whitening effect. According to the ferulic acid and phospholipid complex, ferulic acid and phospholipid are compounded, so that physicochemical properties of ferulic acid are changed, fat solubility, stability and water dispersibility of the complex are enhanced, the transmembrane transport performance of the complex is improved, and then the bioavailability of the complex is increased. After 30 female volunteers at the age of 25-45 use the skin-whitening and skin-caring emulsion containing the ferulic acid and phospholipid complex for 30 days, the melanin content of their faces is lowered obviously, the brightness of their skin is increased, the MI value, L* value and ITA degree value of their skin are remarkably different from original values (P<0.05), and it is indicated that the skin-whitening emulsion has a good human body skin whitening effect.

Description

technical field [0001] The invention relates to a preparation method of a ferulic acid phospholipid complex, and also relates to a whitening cosmetic containing the ferulic acid phospholipid complex and a preparation method thereof. The invention belongs to the technical field of cosmetics. Background technique [0002] Ferulic acid is a phenolic acid ubiquitous in natural plant cell walls. It is one of the active ingredients in traditional Chinese medicine such as ferulae, Chuanxiong, Angelica, Cimicifuga, etc. It is widely used for its good antioxidant, antibacterial, and anticancer effects. applications in the food and pharmaceutical industries. In recent years, with the in-depth research on the biological activity of ferulic acid, it is found that it not only has good pharmacological effects but also has good skin care effects. One is that ferulic acid has good ultraviolet absorption around 290-330nm, and can be added to sunscreen skin care products to protect the skin...

AI Technical Summary

Problems solved by technology

[0005] One of the purposes of the present invention is to provide a ferulic acid phospholipid complex formed by ferulic acid and phospholipids and a preparation method thereof, to improve the hydrophilic and lipophilic physicochemical properties of ferulic acid, improve the solubility of ferulic acid, Improving its bioavailability can effectively solve the problem that it is not easy to absorb, and maintain or enhance its antioxidant activity in different environments

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