Slow-release spectrum antibacterial agent and preparation method thereof

An antibacterial and sustained-release technology, applied in the field of sustained-release spectrum antibacterial agents, can solve the problems of unobtainable raw materials, allergic reactions, volatile iodine, etc., achieve strong and effective bacteriostatic effect, improve bacteriostatic effect, and source raw materials wide range of effects

Active Publication Date: 2016-06-29
NANOLATTIX BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, iodine is highly irritating to the skin and mucous membranes, and iodine is volatile and unstable, and can cause allergic reactions
Povidone iodine, which emerged in the 1960s, improved iodine and overcome the problem that some iodine is vola

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A kind of sustained release type spectrum antibacterial agent, described material comprises by weight: butyl chitosan 50%, medicinal iodine 10%, distilled water 30%, potassium iodate 5%, sodium carbonate-sodium bicarbonate buffer solution 5%.

[0016] The preparation method of the above slow-release broad-spectrum antibacterial agent is as follows: (1) Take 1 part of medicinal iodine and 5 parts of butyl chitosan, mix well and evenly, grind until the diameter is about 1.2-1.8 mm, and obtain a brown-black powder (2) Move it into a wide-mouth container, heat it with an oil bath at 96 degrees Celsius, and keep stirring for about 18 hours until the wet starch test paper is placed at the mouth of the container for 30 seconds until the test paper does not show blue, indicating that the uncomplexed starch has been removed. Free iodine; (3) Add 3 parts of water to make an aqueous solution; (4) Add 0.5 part of potassium iodate to the aqueous solution; (5) 0.5 part of sodium carb...

Embodiment 2

[0018] A kind of sustained release type spectrum antibacterial agent, described material comprises by weight: butyl chitosan 45%, medicinal iodine 10%, distilled water 35%, potassium iodate 5%, sodium carbonate-sodium bicarbonate buffer solution 5%.

[0019] The preparation method of the above-mentioned slow-release broad-spectrum antibacterial agent is as follows: (1) Take 1 part of medicinal iodine and 4.5 parts of butyl chitosan, mix them well and evenly, grind until the diameter is about 1.2-1.8 mm, and obtain a brown-black powder (2) Move it into a wide-mouth container, heat it with an oil bath at 96 degrees Celsius, and keep stirring for about 18 hours until the wet starch test paper is placed at the mouth of the container for 30 seconds until the test paper does not show blue, indicating that the uncomplexed starch has been removed. Free iodine; (3) Add 3.5 parts of water to make an aqueous solution; (4) Add 0.5 parts of potassium iodate to the aqueous solution; (5) 0.5...

Embodiment 3

[0021] A kind of sustained release type spectrum antibacterial agent, described material comprises by weight: butyl chitosan 40%, medicinal iodine 10%, distilled water 40%, potassium iodate 5%, sodium carbonate-sodium bicarbonate buffer solution 5%.

[0022] The preparation method of the above slow-release broad-spectrum antibacterial agent is as follows: (1) Take 1 part of medicinal iodine and 4 parts of butyl chitosan, mix well and evenly, and grind until the diameter is about 1.2-1.8 mm to obtain a brown-black powder (2) Move it into a wide-mouth container, heat it with an oil bath at 96 degrees Celsius, and keep stirring for about 18 hours until the wet starch test paper is placed at the mouth of the container for 30 seconds until the test paper does not show blue, indicating that the uncomplexed starch has been removed. Free iodine; (3) Add 4 parts of water to make an aqueous solution; (4) Add 0.5 part of potassium iodate to the aqueous solution; (5) 0.5 part of sodium ca...

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Abstract

The invention discloses a slow-release spectrum antibacterial agent. According to the technical scheme, the slow-release spectrum antibacterial agent is characterized by comprising 40%-50% of butylchitosan, 10%-15% of medicinal iodine, 10%-40% of distilled water, 1%-5% of potassium iodate and 1%-5% of a sodium carbonate-sodium bicarbonate buffer solution. Through brand-new chelation of carrier butylchitosan and iodine, the antibacterial effect of the antibacterial agent is improved, the iodine content is increased, and the sterilization effect is good. Besides, butylchitosan has a strong and effective antibacterial effect, is clean and easy to obtain and also has a slow release effect, raw materials are widely sourced, and the cost is low.

Description

technical field [0001] The present invention relates to an antibacterial agent, more specifically, it relates to a slow-release spectrum antibacterial agent. Background technique [0002] Due to its poor water solubility, iodine is dissolved in ethanol as an antibacterial agent for clinical disinfection and sterilization. Iodine has been widely used due to its advantages of high efficiency and broad spectrum. However, iodine is highly irritating to the skin and mucous membranes, and iodine is volatile and unstable, and can cause allergic reactions. Povidone iodine, which emerged in the 1960s, improved iodine and overcome the problem that some iodine is volatile and irritating to the skin and mucous membranes. However, the effective iodine content in povidone iodine is not high, and the bactericidal effect is not great , and the price is relatively expensive, and the raw materials are not easy to obtain. Therefore increase antibacterial effect, improve the content of avail...

Claims

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Application Information

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IPC IPC(8): A01N43/16A01N59/12A01P1/00
CPCA01N43/16A01N59/12A01N2300/00
Inventor 杨胜祥傅深渊况燚
Owner NANOLATTIX BIOTECH CO LTD
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