Oral care solution and preparation method thereof

An oral care solution and extraction solution technology, applied in the field of oral care, can solve the problems of restricting the application of propolis to maintain oral health, poor stability of finished products, and high ethanol irritation, so as to maintain the balance of normal oral flora and maintain the flora of the oral cavity. Balanced, low ethanol effect

Active Publication Date: 2016-07-13
ZHEJIANG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the propolis oral care products developed at present are propolis dispersed in ethanol. As the storage time prolongs, the finished product has poor stability, high viscosity, poor taste, and easy precipitation. Earth limits the use of propolis in maintaining oral health
[0004] In order to overcome the disadvantages of the existing propolis oral care solution such as poor stability and mouthfeel, the inventor finally completed the present invention through a large number of experimental studies and result analysis on the basis of summarizing the prior art, providing a basic nursing for oral health product

Method used

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  • Oral care solution and preparation method thereof
  • Oral care solution and preparation method thereof
  • Oral care solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the preparation of oral care solution

[0033] 1. Preparation of propolis solution

[0034] (1) According to the ratio of propolis in grams to absolute ethanol in milliliters of 1:4, let propolis be soaked and extracted in absolute ethanol at room temperature for 5 days, and then separate to obtain the extract E 1 with the extraction residue R 1 ;

[0035] (2) According to the ratio of propolis in grams to aqueous ethanol in milliliters 1:4, let the extraction residue R 1 Soak and extract with 85% ethanol aqueous solution with concentration in volume for 2 days, then separate to obtain extract E 2 with the extraction residue R 2 ;

[0036] (3) Let the extraction residue R 2 Soak and extract with concentration in volume 75% ethanol aqueous solution for 2 days, then separate to obtain extract E 3 with the extraction residue R 3 ;

[0037] (4) the extract E 1 , extract E 2 with extract E 3 Merge, then carry out rotary evaporation and concentration...

Embodiment 2

[0059] Embodiment 2: the preparation of oral care solution

[0060] The implementation steps of this embodiment are as follows:

[0061] A, the preparation of propolis liquid

[0062] According to the ratio of propolis in grams to absolute ethanol in milliliters of 1:8, let the propolis be soaked and extracted in absolute ethanol at room temperature for 2 days, and then separate to obtain the extract E1 and the extraction residue R1;

[0063] Next, according to the ratio of propolis in grams to aqueous ethanol in milliliters of 1:3, the extraction residue R1 was soaked and extracted in an 85% ethanol aqueous solution in volume for 2 days, and then separated to obtain the extraction solution E2 and the extraction residue R2;

[0064] Next, according to the ratio of propolis in grams to aqueous ethanol in milliliters of 1:1, the extraction residue R2 was soaked in an aqueous ethanol solution with a concentration of 75% in volume for extraction for 1 day, and then separated to o...

Embodiment 3

[0087] Embodiment 3: the preparation of oral care solution

[0088] The implementation steps of this embodiment are as follows:

[0089] A, the preparation of propolis liquid

[0090] According to the ratio of propolis in grams to absolute ethanol in milliliters of 1:6, let the propolis be soaked and extracted in absolute ethanol at room temperature for 4 days, and then separate to obtain the extract E1 and the extraction residue R1;

[0091] Next, according to the ratio of propolis in grams to aqueous ethanol in milliliters of 1:2, the extraction residue R1 is soaked in an aqueous ethanol solution with a concentration of 85% in volume for extraction for 1 day, and then separated to obtain the extraction solution E2 and the extraction residue R2;

[0092] Next, according to the ratio of propolis in grams to aqueous ethanol in milliliters of 1:2, the extraction residue R2 was soaked in an aqueous ethanol solution with a concentration of 75% in volume for extraction for 2 days,...

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Abstract

The invention provides an oral care solution which contains propolis extract, lecithin, chrysanthemum indicum extract, licorice extract, menthol, mint essence and preservative.The preparation method comprises the steps of soaking propolis with absolute ethyl alcohol at the room temperature, conducting extraction, then conducting ultrasonic extraction with ethanol water, and conducting rotary evaporation and concentration, so that a propolis extracting solution is obtained; then adding a lecithin solution and other traditional Chinese medicine ingredients while stirring is conducted, so that the oral care solution is obtained.By means of the oral care solution and the preparation method thereof, the technical defects that conventional propolis oral care solutions generally adopt ethanol as solvent, therefore products are prone to precipitation, irritation is great, and the products are not stable are overcome, and the oral care solution is free of irritation, stable in performance, safe and reliable.The oral care solution contains no chemical bacteriostatic agent and is free of toxic or side effect.The propolis is adopted as the main active constituent, the role that the propolis can inhibit harmful bacteria in the oral cavity is given full play, meanwhile, beneficial bacteria are protected, and normal flora balance of the oral cavity is maintained.The propolis care solution is low in ethanol content and free of irritation, and the obtained oral care solution is stable.

Description

technical field [0001] The invention belongs to the technical field of oral care and relates to an oral care solution, in particular to a propolis oral care solution and a preparation method thereof. Background technique [0002] As we all know, the mouth and throat are the passages for eating and breathing, and the only way for drinking water to enter the human body, which are closely related to human health and survival. Therefore, its health has an important impact on the human body. Factors such as bacterial and viral infections, air pollution, excessive use of voice, tobacco and alcohol, and spicy and hot food can easily lead to oral problems and throat inflammation. It is easy to develop into periodontitis, chronic pharyngitis and so on. Although there are many drugs for the treatment of chronic pharyngitis, clinical practice has proved that not only the curative effect is not very satisfactory, but also the side effects are large. [0003] The unique flavonoids and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/97A61K8/34A61K8/55A61Q11/00A61P31/04A61P1/02
CPCA61K8/34A61K8/553A61K8/97A61K8/988A61Q11/00
Inventor 张翠平胡福良孙德官
Owner ZHEJIANG UNIV
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