Water-dispersible transparent astaxanthin emulsion and preparation method

A kind of astaxanthin and dispersive technology, which is applied in the direction of emulsion transportation, food ingredients as emulsifiers, medical preparations of non-active ingredients, etc., to achieve the effects of stable properties, expanded application range, good solubility and water dispersibility

Active Publication Date: 2016-08-10
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there have been no reports at home and abroad about converting astaxanthin extract or oleoresin into transparent astaxanthin emulsion with good water dispersibility through emulsification technology.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0031] The preparation method of water-dispersible transparent astaxanthin emulsion of the present invention comprises the following steps:

[0032] a) Preparation of oil phase: dissolving astaxanthin in a solvent to make astaxanthin solution, which is the oil phase, the mass volume concentration of the astaxanthin solution is 1-30 mg / ml, and the solvent is edible The oil is preferably one of tea tree oil, sunflower oil or lemon essential oil, and the astaxanthin uses astaxanthin oleoresin as a raw material.

[0033] The above-mentioned solvent has the following characteristics: no reaction with astaxanthin; high solubility of astaxanthin in the above-mentioned solvent; good fluidity at high concentration; low price and easy availability; and edibility.

[0034] b) Preparation of the water phase: water or a mixture of glycerin and water is used as the water phase, and in the mixture of glycerin and water, the volume ratio of glycerin and water is 8:1-1:5.

[0035] A large num...

Embodiment 1

[0038] The raw material of astaxanthin is astaxanthin oleoresin, wherein the content of astaxanthin is 5%, that is, 100g of oleoresin contains 5g of astaxanthin.

[0039] The water-dispersible astaxanthin emulsion of embodiment 1 comprises oil phase, water phase and Tween 80 (emulsifier), and its composition is as follows:

[0040] The oil phase is an astaxanthin solution, including astaxanthin and sunflower oil, and the mass volume concentration of the astaxanthin solution is 30 mg / mL;

[0041] The aqueous phase is water;

[0042] The volume ratio of oil phase and Tween 80 is 1:3;

[0043] The volume ratio of the mixture of water phase, oil phase and Tween 80 is 1:1.

[0044] The preparation method of the water-dispersible transparent astaxanthin emulsion of embodiment 1 comprises the steps:

[0045] a) Preparation of oil phase: dissolving astaxanthin oleoresin containing 1500mg astaxanthin in 50mL sunflower oil to make astaxanthin solution, which is the oil phase, the mas...

Embodiment 2

[0049] The raw material of astaxanthin is astaxanthin oleoresin, wherein the content of astaxanthin is 5%, that is, 100g of oleoresin contains 5g of astaxanthin.

[0050] The water-dispersible astaxanthin emulsion of the present invention comprises oil phase, water phase and Tween 60, and its composition is as follows:

[0051] The oil phase is an astaxanthin solution, including astaxanthin and lemon essential oil, the mass volume concentration of the astaxanthin solution is 1 mg / mL, the water phase is a mixture of glycerin and water, and the mixture of glycerin and water includes glycerin and The volume ratio of water is 8:1;

[0052] The volume ratio of oil phase and Tween 60 is 3:1;

[0053] The volume ratio of the mixture of water phase, oil phase and Tween 60 is 1:9.

[0054] The preparation method of the water-dispersible transparent astaxanthin emulsion of embodiment 2 comprises the steps:

[0055] a) Preparation of oil phase: Dissolve astaxanthin oleoresin containing ...

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Abstract

The invention belongs to dosage form technology of functional additives, and particularly relates to a water-dispersible transparent astaxanthin emulsion and a preparation method. The astaxanthin emulsion comprises an oil phase, a water phase and an emulsifier, the oil phase is an astaxanthin solution and comprises astaxanthin and a solvent, mass-volume concentration of the astaxanthin solution is 1-30 mg/mL, the water phase is water or a mixture of glycerin and water, the solvent is edible oil, a volume ratio of the oil phase to the emulsifier is 1:3:3:1, and a volume ratio of the water phase to mixed liquid of the oil phase and the emulsifier is greater than or equal to 1:9. The preparation method includes: preparing the oil phase, preparing the water phase, and preparing the emulsion. The water-dispersible astaxanthin emulsion has high solubility and water dispersity, bioavailability of the water-dispersible astaxanthin emulsion is improved, and various physiological active functions of the water-dispersible astaxanthin emulsion are brought into effective play.

Description

technical field [0001] The invention belongs to the dosage form preparation technology of functional additives, and in particular relates to a water-dispersed astaxanthin transparent emulsion and a preparation method thereof. Background technique [0002] Astaxanthin is composed of 4 isoprene double bonds connected end to end, with a total of 11 conjugated double bonds and a β-ionone ring structure composed of 2 isoprene units at both ends. The molecular formula is C 40 h 52 o 4 , with a relative molecular weight of 596.86, is a ketocarotenoid. Astaxanthin is fat-soluble, insoluble in water, pink in color, and has a melting point of about 224°C. It has a strong pigmentation ability. As a functional pigment, it can be used as a yellow to orange-red pigment colorant . At the same time, astaxanthin has a strong antioxidant function and anti-photosensitivity effect, and its anti-photosensitivity effect is stronger than that of β-carotene. It can remove free radicals in the b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/06A61K8/35A61K31/122A61K9/107A61K47/14A61K47/44A23L2/58A23L5/44A23L33/10A23K20/179
CPCA23L2/58A23V2002/00A61K8/06A61K8/35A61K9/107A61K31/122A61K47/14A61K47/44A23V2200/04A23V2200/222A23V2250/18
Inventor 赵广华陈海马长伟
Owner CHINA AGRI UNIV
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