Method for preparing traditional Chinese medicine composition for treating diabetic nephropathy

A technology for diabetic nephropathy and a composition is applied in the field of preparing a traditional Chinese medicine composition for treating diabetic nephropathy, which can solve the problems of not very significant effect, and achieve the effects of protecting renal function, low cost and high efficiency.

Inactive Publication Date: 2016-10-12
YANTAI HUAWEN XINXIN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese medicine composition has the effect of reducing the excretion of proteinuria and prolonging the progress of diabetic nephropathy, but the effect of the Chinese medicine composition on lowering blood sugar, tonifying the kidney and invigorating the spleen is not very significant

Method used

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  • Method for preparing traditional Chinese medicine composition for treating diabetic nephropathy
  • Method for preparing traditional Chinese medicine composition for treating diabetic nephropathy
  • Method for preparing traditional Chinese medicine composition for treating diabetic nephropathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The pharmaceutical composition of Example 1 of the present invention includes the following preparation raw materials in parts by weight: 5 parts of total flavonoids of Moringa oleifera leaves, 1 part of stilbene glycosides, 1 part of ginsenoside Rb1, 1 part of ginsenoside Rg1, 1 part of ginsenoside Rd, 1 part Ginsenoside Re, 1 part Ginkgolide, 1 part Kaempferol, and 1 part Quercetin.

[0033] The preparation method is as follows:

[0034] (1) Preparation of total flavonoids from Moringa oleifera leaves:

[0035] A: take Moringa leaf, dry, pulverize, cross 45 mesh sieves, obtain Moringa leaf powder;

[0036] B: Take the Moringa oleifera leaf powder obtained in step A, add petroleum ether, reflux and degrease 3 times at 68° C. for 6 hours each time, filter, remove the filtrate, and dry the filter residue to obtain a dry filter residue;

[0037] C: Add 70% ethanol to the dried filter residue obtained in step B, process it at a microwave power of 600W for 7 minutes, extr...

Embodiment 2

[0041] The pharmaceutical composition of Example 2 of the present invention includes the following preparation raw materials in parts by weight: 30 parts of total flavonoids of Moringa oleifera leaves, 18 parts of stilbene glycosides, 10 parts of ginsenoside Rb1, 10 parts of ginsenoside Rg1, 2 parts of ginsenoside Rd, 4 parts Ginsenoside Re, 4 parts Ginkgolide, 2 parts Kaempferol and 2 parts Quercetin.

[0042] The preparation method is the same as in Example 1.

Embodiment 3

[0044] The pharmaceutical composition of Example 3 of the present invention includes the following preparation raw materials in parts by weight: 20 parts of total flavonoids of Moringa oleifera leaves, 10 parts of stilbene glycosides, 5 parts of ginsenoside Rb1, 5 parts of ginsenoside Rg1, 1.5 parts of ginsenoside Rd, 2 parts ginsenoside Re, 2 parts ginkgolide, 1.5 parts kaempferol and 1.5 parts quercetin.

[0045] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a method for preparing traditional Chinese medicine composition for treating diabetic nephropathy and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from raw materials as follows: total flavones of moringa oleifera leaves, stibene glucoside, ginsenoside Rb1, ginsenoside Rg1, ginsenoside Rd, ginsenoside Re, ginkgolide, kaempferol and quercetin. The prepared traditional Chinese medicine composition has high synergistic effect, used as drugs for treating the diabetic nephropathy through combination, and clinical trials verify that quite remarkable effect is obtained.

Description

[0001] This application is an invention patent application submitted by the applicant Qingdao Lanshengyang Pharmaceutical Biotechnology Co., Ltd. (the name of the invention is: a traditional Chinese medicine composition for the treatment of diabetic nephropathy and its preparation method, the application number is: 2015104816935, and the application date is: 2015 August 10, 2009) divisional application. technical field [0002] The invention belongs to the technical field of traditional Chinese medicines, in particular to a method for preparing a traditional Chinese medicine composition for treating diabetic nephropathy. Background technique [0003] Diabetic nephropathy is one of the common complications of diabetes, which is a metabolic disease characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired biological action, or both. The long-term existence of diabetes complicated by high blood sugar can easily lead to chronic damage an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P3/10A61P13/12A61K31/7034A61K31/704A61K31/365A61K31/352
CPCA61K31/352A61K31/365A61K31/7034A61K31/704A61K36/185A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 刘春同
Owner YANTAI HUAWEN XINXIN PHARMA CO LTD
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