Extract of total flavonoids from water lily flower and its preparation method and application

A technology of water lily flower and total flavonoids, which is applied in the direction of medical formula, drug combination, plant raw materials, etc., can solve the problems of water lily flower separation and purification process blank, and achieve the effect of easy industrial production, low cost, and good anti-hepatitis effect

Active Publication Date: 2019-11-12
XINJIANG INST OF MATERIA MEDICA
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention provides an extract of total flavonoids from water lily flower and its preparation method and its application in the preparation of drugs for preventing and treating liver damage, which overcomes the above-mentioned deficiencies in the prior art, and can effectively solve the problem of blank separation and purification process of water lily flower

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Extract of total flavonoids from water lily flower and its preparation method and application
  • Extract of total flavonoids from water lily flower and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1, the total flavonoid extract of the water lily flower contains 50% to 80% by weight of flavonoids, 1.2% to 3.0% by weight of isostrictiniin, and 9.0% to 16.0% by weight of firework glycosides. , The weight percentage of the glucosinolate content is 4.5% to 8.0%.

Embodiment 2

[0025] Example 2. The total flavonoid extract of the water lily flower contains 50% or 80% by weight of flavonoids, 1.2% or 3.0% by weight of isostrictiniin, and 9.0% or 16.0% by weight of firework glycosides. , The weight percentage of the glucosinolate content is 4.5% or 8.0%.

Embodiment 3

[0026] In Example 3, the total flavonoids of the water lily extract was obtained according to the following preparation method: In the first step, the water lily was selected as the raw material, the water lily was added to the ethanol aqueous solution and boiled and then refluxed for 1 to 3 times. Concentrate to obtain a primary extract; in the second step, dilute the primary extract with deionized water to obtain the first diluent. The first diluent is adsorbed by a macroporous resin column, followed by deionized water with a volume percentage of 30%. Eluted with ethanol and 50% to 70% by volume ethanol, collect the 50% to 70% ethanol eluate by volume, and concentrate the ethanol eluate to obtain the second extract; the third step is to immerse the second extract The paste is diluted with deionized water to obtain the second dilution. The second dilution is adsorbed on a polyamide resin column, and eluted with deionized water after adsorption. After eluted with deionized water...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to the technical field of nymphaea candida presl extracts and relates to a nymphaea candida presl total flavonoid extract as well as a preparation method and application thereof. The nymphaea candida presl total flavonoid extract is prepared from the following components in percentage by weight: 50 percent to 80 percent of flavonoid, 1.2 percent to 3.0 percent of isostrictiniin, 9.0 percent to 16.0 percent of nicotiflorin and 4.5 percent to 8.0 percent of astragalin. The invention provides a method for separating and purifying the nymphaea candida presl total flavonoid extract; the flavonoid components are extracted from the nymphaea candida presl by a method with combination of macroporous resin and polyamide resin. The nymphaea candida presl total flavonoid extract has the advantages that the cost is low, the pollution is avoided, and the industrial production is easy to implement; meanwhile, the nymphaea candida presl total flavonoid extract has a good anti-hepatitis effect, is high in effectiveness and low in toxicity, and can be applied to prevention and treatment of liver injury.

Description

Technical field [0001] The present invention relates to the technical field of Nymphaea extract, and is a Nymphaea total flavonoid extract and a preparation method and application thereof. Background technique [0002] Liver damage caused by viruses, alcohol, drugs and other factors is a common clinical disease. Severe or persistent liver damage can lead to liver fibrosis, even liver cirrhosis, liver cancer and other diseases. Prevention and treatment of liver damage is an important part of clinical liver disease treatment. In recent decades, it has become a hot field in the research and development of therapeutic drugs for liver diseases to find active ingredients that can prevent liver damage from traditional Chinese medicines and natural medicines. Water lily is the dry bud of the snow-white water lily Nymphaea candida Presl. It has the effects of clearing away heat, detoxifying, calming and soothing the nerves. It is used for the treatment of cold and fever, headache and coug...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/62A61P1/16
CPCA61K36/62A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 赵军徐芳吉腾飞李晨阳陈燕詹羽姣
Owner XINJIANG INST OF MATERIA MEDICA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap