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Itching-relieving repair solution containing silver-ion bactericide, preparation method and application thereof

A technology of silver ion antibacterial agent and repair solution, which is applied in the field of medicine, can solve the problems of large oral mucosa irritation, acidity change, and unsatisfactory antibacterial effect, and achieve high and stable antibacterial efficiency

Active Publication Date: 2016-11-16
广州洁康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Not only that, whether the existing formula technology adopts traditional aldehyde acid antibacterial agents (formaldehyde, benzoic acid), chlorine preparations (triclosin, chlorhexidine acetate, chlorine dioxide, hypochlorous acid), or relatively novel Both nano-silver antibacterial agents and colloidal silver antibacterial agents have the defects of unsatisfactory antibacterial effect and poor stability (discoloration, acidity change)
[0006] In addition, in the prior art, most of the skin and oral mucosa repair care ingredients use some western medicine ingredients such as nicotinamide, chlorpheniramine, lidocaine, etc., which are more irritating to the skin and oral mucosa; Source Chinese herbal medicine ingredients such as Scutellaria baicalensis, Tieshidou, Sophora flavescens, Cnidium chinensis, Baibu, Cortex Phellodendri, etc., which are also irritating to the skin and oral mucosa
In addition, even if you choose to add less irritating Chinese herbal medicine ingredients in the skin and oral mucosa repair care ingredients in the prior art repair care solution, what you add is Chinese herbal medicine extract, the amount of active ingredients is relatively small, and the repair care effect is not ideal.
However, powders of Chinese herbal medicines with the same source of medicine and food are usually directly used in swallowing medicines, but there are few reports about the direct effect on the affected area when used for external medicine.

Method used

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  • Itching-relieving repair solution containing silver-ion bactericide, preparation method and application thereof
  • Itching-relieving repair solution containing silver-ion bactericide, preparation method and application thereof
  • Itching-relieving repair solution containing silver-ion bactericide, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] An antipruritic and repairing liquid containing silver ion antibacterial agent, comprising the following components by mass percentage: 10% glycerin, 10% propylene glycol, 6% honeysuckle extract, 6% wild chrysanthemum extract, and 6% purslane extract %, centella asiatica extract 6%, peppermint extract 6%, aloe vera extract 6%, silver ion antibacterial agent 20%, and the rest is deionized water. This is the present embodiment 1 formula.

[0033] At the same time, the following three comparative formulas were made, namely:

[0034] Comparative formula 1: This comparative formula includes the following components by mass percentage: glycerin 10%, propylene glycol 10%, honeysuckle extract 6%, wild chrysanthemum extract 6%, purslane extract 6%, centella asiatica extract Herbal extract 6%, peppermint extract 6%, aloe extract 6%, and the rest is deionized water.

[0035] Comparative formula 2: This comparative formula includes the following components by mass percentage: gly...

Embodiment 2

[0045] An antipruritic repairing liquid containing silver ion antibacterial agent, comprising the following components by mass percentage: 2% glycerin, 3% propylene glycol, 0.4% peppermint extract, 6% witch hazel extract, 8% alum, silver 8% ion antibacterial agent, the rest is deionized water. This is the formula of the present embodiment 2.

[0046] At the same time, the following three comparative formulas were made, namely:

[0047] Comparative formula 4: This comparative formula includes the following components by mass percentage: 2% glycerin, 3% propylene glycol, 0.4% peppermint extract, 6% witch hazel extract, 8% alum, and the rest is deionized water.

[0048] Comparative formula 5: This comparative formula includes the following components by mass percentage: 2% glycerin, 3% propylene glycol, 0.4% peppermint extract, 8% alum, 8% silver ion antibacterial agent, and the rest is deionized water.

[0049] Comparative formula 6: This comparative formula includes the follo...

Embodiment 3

[0057] An antipruritic repair solution containing silver ion antibacterial agent, comprising the following components by mass percentage: glycerin 10%, propylene glycol 10%, peppermint extract 2%, witch hazel extract 3%, silver ion antibacterial agent 4 %, and the rest is deionized water.

[0058] The formula of Example 3, the sterilizing, moisturizing and anti-aging components of silver ions, combined with the sterilizing and repairing effects of plant extracts, can make the vaginal environment in a good state and prevent gynecological diseases, so that women’s vaginas can be kept healthy for a long time state. Apply the formula of this example to the vaginas of 30 women aged 35-60, 2-3 times a day, 1 gram each time. After 15 days of continuous use, some people obviously feel that the vagina is more lubricated. Use a colposcope to detect this part of the population , it was found that the vaginal mucosa of this part of the population remained firm and smooth; after 20 days o...

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Abstract

The invention relates to the technical field of medicines, and particularly relates to an itching-relieving repair solution containing silver-ion bactericide. The itching-relieving repair solution is prepared from the following components in percentage by mass: 2-10 percent of glycerinum, 3-10 percent of propylene glycol, 0.4-36 percent of edible and medicinal herbal extract and the balance of silver-ion bactericide and water, wherein the dosage of the silver-ion bactericide ensures 1-5ppm of silver ions in the itching-relieving repair solution; the edible and medicinal herbal extract is one or more of honeysuckle extract, chrysanthemum indicum flower extract, portulaca oleracea extract, centella asiatica extract, peppermint extract and aloe extract, and an arbitrary medicinal and edible herbal extract is below 6 percent by mass of the itching-relieving repair solution. The itching-relieving repair solution is mild, safe, efficient, multi-effect acting and broad-spectral.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a sterilizing and antipruritic repair liquid, a preparation method and application. Background technique [0002] Researchers at home and abroad have extensively screened fungicides according to the purpose of sterilization and the characteristics of disinfection objects, but no ideal antibacterial agent has been found so far. Aldehyde and acid antibacterial agents (formaldehyde, benzoic acid) have a wide bactericidal spectrum, but are highly toxic, corrosive, and irritating to oral mucosa and skin; chlorine preparations (triclosin, chlorhexidine acetate, dioxide Chlorine, hypochlorous acid) has low effective concentration, fast action speed, and stable properties, but is easily affected by organic matter, acid, alkali, and other physical and chemical factors, and is also more irritating to oral mucosa and skin. [0003] Therefore, inorganic antibacterial agents have entered pe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K36/287A61K36/185A61K36/23A61K36/534A61K36/886A61K36/896A61K33/38A61P31/02A61P1/02A61P17/04A61P15/02A61P17/00A61K33/06
CPCA61K33/06A61K33/38A61K36/185A61K36/23A61K36/287A61K36/355A61K36/534A61K36/886A61K36/896A61K2300/00
Inventor 叶符材
Owner 广州洁康医药科技有限公司
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