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Sodium phosphate oral solution composition and preparation method thereof

A technology of oral solution and sodium phosphate salt, which is applied to the active ingredients of phosphorus compounds, drug combinations, and pharmaceutical formulas. It can solve the problems of low total number of bacteria and slow bowel cleansing effect, and achieve the goal of promoting excretion, relieving gastrointestinal discomfort, and accurate feeding Effect

Inactive Publication Date: 2016-12-21
HAINAN SANFENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The total number of bacteria in the solution obtained by this method is extremely low, which reduces the stimulation of the solution to the intestinal tract, but its intestinal cleansing effect is slow, and there is a situation of gastrointestinal discomfort

Method used

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  • Sodium phosphate oral solution composition and preparation method thereof
  • Sodium phosphate oral solution composition and preparation method thereof
  • Sodium phosphate oral solution composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A sodium phosphate oral solution composition, the raw materials for preparing the oral solution composition include: disodium hydrogen phosphate, glycerin, acesulfame potassium, sodium benzoate, natural ginger juice essence, natural lemon essence, phosphoric acid and purified water, The addition amount of described raw material sees prescription 1, and wherein, the weight of disodium hydrogen phosphate is 1.529 times of phosphoric acid, and the weight of glycerin is 5.16% of phosphoric acid.

[0020]

[0021] The preparation method of above-mentioned sodium phosphate oral solution composition, comprises the following steps:

[0022] 1) Add 450ml of purified water to the batching tank, add disodium hydrogen phosphate and glycerin while stirring, add sodium benzoate (stir with purified water before adding to dissolve and then pour), add acesulfame potassium (use stainless steel before adding Add purified water into the bucket and stir to dissolve and then pour it into)...

Embodiment 2

[0028] A sodium phosphate oral solution composition, the raw materials for preparing the oral solution composition include: disodium hydrogen phosphate, glycerin, acesulfame potassium, sodium benzoate, natural ginger juice essence, natural lemon essence, phosphoric acid and purified water, The addition amount of described raw material sees prescription 2, and wherein, the weight of disodium hydrogen phosphate is 1.525 times of phosphoric acid, and the weight of glycerin is 5.13% of phosphoric acid.

[0029]

[0030] The preparation method of above-mentioned sodium phosphate oral solution composition, comprises the following steps:

[0031] 1) Add 450ml of purified water to the batching tank, add disodium hydrogen phosphate and glycerin while stirring, add sodium benzoate (stir with purified water before adding to dissolve and then pour), add acesulfame potassium (use stainless steel before adding Add purified water into the bucket and stir to dissolve and then pour it into)...

Embodiment 3

[0037]A sodium phosphate oral solution composition, the raw materials for preparing the oral solution composition include: disodium hydrogen phosphate, glycerin, sucralose, clove, licorice, honeysuckle, perilla, purple sweet potato extract, yacon, dragon fruit .

[0038]

[0039] The preparation method of above-mentioned sodium phosphate oral solution composition, comprises the following steps:

[0040] 1) Wash the ginger, cut it into slices, add water equivalent to 100% of the total amount of ginger, squeeze the juice, and filter to obtain ginger juice;

[0041] 2) Wash the lemons, cut them into slices, add water equivalent to 100% of the total amount of lemons, squeeze the juice, and filter to obtain lemon juice;

[0042] 3) Add 450ml of purified water to the batching tank, add disodium hydrogen phosphate and glycerin while stirring, add sucralose (use a stainless steel bucket to add purified water and stir to dissolve before pouring in), add licorice, clove, honeysuckle...

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PUM

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Abstract

The invention discloses a sodium phosphate oral solution composition and a preparation method of the sodium phosphate oral solution composition. The raw materials for preparing the oral solution composition comprise disodium hydrogen phosphate, ginger juice, lemon juice, phosphoric acid, glycerin and purified water, and the addition amounts of the raw materials for preparing each liter of the oral solution composition are as follows: 2.5 to 250g of phosphoric acid, 5 to 7g of the ginger juice and 4 to 6g of the lemon juice; the weight of disodium hydrogen phosphate is 1.4-1.6 times of that of phosphoric acid, and the weight of the glycerin is 4%-6% of that of phosphoric acid. The preparation comprises the following steps: firstly adding disodium hydrogen phosphate and glycerin into purified water, then adding the ginger juice and lemon juice, then adding phosphoric acid, stirring heating to 60-65 DEG C, digesting for 0.5-1 hour, finally adding purified water to fix volume and uniformly stirring. The sodium phosphate oral solution composition disclosed by the invention can effectively inhibit ginger to generate and transform carcinogen safrole and promote a gastrointestinal medicine guiding effect of ginger components, has an obvious synergistic effect and a good intestine cleaning effect, can further relieve gastrointestinal discomfort, can be used as a mild and safe intestine cleaning product and further can be used as a medicine, food and drink.

Description

technical field [0001] The invention relates to the technical field of oral bowel cleansing agents, in particular to a sodium phosphate oral solution composition and a preparation method thereof. Background technique [0002] Inventor Zhang Hai et al. introduced a preparation method of sodium phosphate oral solution in "A Preparation Method for Sodium Phosphate Salt Oral Solution" with application number 200910060341.7 on August 13, 2009. The steps include dissolving raw materials, boiling off Bacteria and filter sterilization to obtain sodium phosphate oral solution. The total number of bacteria in the solution obtained by the method is extremely low, which reduces the stimulation of the solution to the intestinal tract, but the intestinal cleansing effect is relatively slow, and there is a situation of gastrointestinal discomfort. Contents of the invention [0003] In view of this, the present invention provides a sodium phosphate salt oral solution composition and a pr...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/08A61K47/10A61K47/02A61P1/10A61K33/42
CPCA61K36/9068A61K9/0095A61K33/42A61K36/076A61K36/185A61K36/285A61K36/33A61K36/355A61K36/484A61K36/53A61K36/535A61K36/61A61K36/752A61K36/8945A61K36/8998A61K47/02A61K47/10A61K2236/31A61K2236/331A61K2300/00
Inventor 汪贻元黄广伟谢剑波黄卫英梁文惠
Owner HAINAN SANFENG PHARMA CO LTD
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