A temperature control method for magnetic fluid hyperthermia based on temperature feedback and a hyperthermia instrument

Abstract

The invention discloses a magneto-fluid thermotherapy temperature control method based on temperature feedback and a thermotherapy instrument thereof. The method comprises the following steps that (1) a triangular wave excitation magnetic field is generated by adopting a pre-excitation mode; (2) the response signal of the triangular wave excitation magnetic field is eliminated, a target area magnetized response signal is acquired and inversion of current temperature of a target area is performed; (3) a radio frequency magnetic field generation device is controlled to heat the target area according to the current temperature and a control strategy function; (4) the temperature of the target area is measured at a measurement end; (5) the temperature of the target area after last time of heating and the temperature of the target area before next time of heating are predicted through the measured temperature of the target area, and the radio frequency magnetic field generation device is controlled in a feedback way according to the predicted temperature so as to adjust heating parameters; and (6) the steps (4)-(5) are repeated until the temperature is stabilized in a thermotherapy temperature window. According to the method and the thermotherapy instrument thereof, the temperature of the target area is controlled through temperature feedback so as to realize accurate temperature control in magneto-fluid thermotherapy.

Description

technical field [0001] The invention belongs to the technical field of real-time intelligent temperature control, and more specifically relates to a temperature feedback-based magnetic fluid hyperthermia temperature control method and a hyperthermia instrument. Background technique [0002] The data shows that 42°C-45°C is the window temperature for the gradual necrosis of cancer cells and the survival of normal cells. When the local temperature of the body tissue exceeds 42°C, the tumor tissue will begin to appear congestion or even coagulation necrosis, while the temperature within 45°C will not Causes irreversible damage to normal tissue. Tumor hyperthermia takes advantage of the significant difference in temperature tolerance between tumor tissue and normal tissue, and achieves the purpose of destroying tumor tissue by heating the tumor to keep its temperature at the window temperature. [0003] Magnetic fluid is a new type of functional material mixed with magnetic nan...

AI Technical Summary

Problems solved by technology

However, when the magnetic fluid acts on the lesion, how to realize the precise control of the local temperature of the lesion has not yet been studied.

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