A kind of kelp root hypoglycemic product and its preparation method and application

A technology of hypoglycemic and kelp root, applied in the field of medicine, can solve the problem of low activity of hypoglycemic components, and achieve the effects of no toxic side effects, increased IC50, and sufficient raw materials
CN106539825BInactive Publication Date: 2020-06-09QINGDAO JIARILONG SEAFOOD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
QINGDAO JIARILONG SEAFOOD
Publication Date
2020-06-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a laminaria japonica root hypoglycemic product and a preparation method and application thereof. The preparation method comprises the following steps that laminaria japonica roots are taken and extracted for multiple times through ethyl alcohol, an antioxidant is added during the extraction process, and an extracted concentrate is obtained; and extract liquor is added into the extracted concentrate for extraction, an antioxidant is added in the extraction process, drying is conducted, and the laminaria japonica root hypoglycemic product is obtained. The laminaria japonica roots used in the preparation method is sufficient in raw material, and the laminaria japonica root hypoglycemic product is definite in hypoglycemic effect and free of toxic and side effects, and is a safe and effective hypoglycemic product; the hypoglycemic product obtained through the preparation method has an obvious inhibition effect on alpha-glucosidase, reaches 140 [mu]g / ml in IC50, and is a noncompetitive inhibitor to the alpha-glucosidase; and an antioxidant vitamin C is added, compared with the prior art, the hypoglycemic effect IC50 is doubled or above, and meanwhile, the product yield is increased by several times.
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Description

technical field

[0001] The invention relates to the field of medicine, in particular to a kelp root hypoglycemic product and a preparation method and application thereof. Background technique

[0002] Diabetes is a major disease that seriously endangers human health. It has many and serious complications and is difficult to cure. There are tens of millions of diabetic patients in my country, which is one of the countries with the largest number of diabetic patients in the world. Currently, clinically used drugs for the treatment of diabetes include sulfonylureas and biguanides. However, long-term use of these drugs has serious side effects. For example, sulfonylureas have adverse reactions of hypoglycemia; biguanides have gastrointestinal side effects. Insulin replacement drugs are relatively safe and effective drugs at this stage, but they are expensive and have restrictions on storage conditions. Therefore, it is of great significance to look for hypoglycemic products th...

Claims

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