A kind of kelp root hypoglycemic product and its preparation method and application
A technology of hypoglycemic and kelp root, applied in the field of medicine, can solve the problem of low activity of hypoglycemic components, and achieve the effects of no toxic side effects, increased IC50, and sufficient raw materials
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[0021] Disclosed is a preparation method of a kelp root hypoglycemic product, comprising the following steps: taking kelp root and extracting it multiple times with ethanol, adding antioxidants during the extraction process to obtain an extraction concentrate; adding the extraction concentrate to an extraction liquid for extraction, the extraction process Antioxidants are added and dried to obtain the hypoglycemic product of kelp root. Preferably, the antioxidant is vitamin C.
[0022] Among them, the active ingredients contained in the hypoglycemic substance extracted from kelp root are easy to oxidize, adding antioxidants during the extraction and separation process can significantly increase the content of the hypoglycemic substance. Antioxidants can also be vitamin A, vitamin E, and glutathione. Adding the antioxidant vitamin C during the extraction process increases the IC50.
[0023] In some illustrative embodiments, the extraction process or the amount of antioxidant a...
Embodiment 1
[0028] Take 100kg of naturally air-dried kelp root, dry at 60°C for 24 hours, take it out, grind it into powder, pass through a 60-mesh sieve, add more than 80% ethanol according to the solid-liquid ratio of 1:5, and add 0.1% vitamin C at the same time, and reflux at 60°C Extract for 2 hours, filter the extract, extract the filter residue twice according to the above method, combine the filtrate, and dry under reduced pressure to obtain the extract concentrate of kelp root.
[0029] Add 5 times the amount of ethyl acetate and 0.1% vitamin C to the extract concentrate obtained from kelp root, stir and extract at room temperature for 24 hours, siphon the upper layer solution, and extract the lower layer precipitation twice with the same method, combine the extracts, reduce Press and dry to obtain the product A for lowering blood sugar of seaweed root.
Embodiment 2
[0031] Take 100kg of naturally air-dried kelp root, dry it at 60°C for 24 hours, take it out, grind it into powder, pass it through a 60-mesh sieve, add more than 80% ethanol according to the solid-liquid ratio of 1:5, extract at 60°C for 2 hours, and filter the extract. The filter residue was extracted twice according to the above method, and the filtrates were combined and dried under reduced pressure to obtain the extract concentrate of kelp root.
[0032] Add 5 times the amount of ethyl acetate and 0.1% vitamin C to the extract concentrate obtained from kelp root, stir and extract at room temperature for 24 hours, siphon the upper layer solution, and extract the lower layer precipitation twice with the same method, combine the extracts, reduce Press and dry to obtain the kelp root hypoglycemic product B.
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