Medicine for treating postherpetic neuralgia and preparation method of medicine

A technology for postherpetic neuralgia and herpes zoster, which is applied in the fields of medicine and pharmacy, can solve the problems of PHN patients’ condition not being effectively controlled, poor tolerance and compliance of patients, and unclear pathological mechanism of PHN. Considerable economic and social benefits, easy to carry and take, good market prospects

Inactive Publication Date: 2017-04-19
傅天锡
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The problem to be solved by the present invention is: because the pathological mechanism of PHN is not yet clear, the current various treatment methods all have great limitations in the implementation process, such as many adverse reactions of western medicine, easy to produce drug dependence, and patient tolerance. Poor performance and compliance, difficult quality control of traditional Chinese medicine compound preparations, inconvenient administration, inaccurate curative effect, etc. The above-mentioned problems existing in existing drugs make the condition of quite a few PHN patients unable to be effectively controlled

Method used

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  • Medicine for treating postherpetic neuralgia and preparation method of medicine
  • Medicine for treating postherpetic neuralgia and preparation method of medicine
  • Medicine for treating postherpetic neuralgia and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A medicine for treating postherpetic neuralgia, the medicine is made of the following raw materials in weight ratio:

[0034]

[0035]

[0036] The preparation method is as follows:

[0037] 1) Dipsacus, Pangui, Notoginseng, Chuanxiong, Turmeric, Cardamom, Frankincense, Myrrh, Curcuma, Woody Fragrance, Liu Jinu, Duhuo, Schizonepeta, Clematis, Paeoniae Alba, Amaranth, Red Flower, Amomum, Imperatae Rhizome, Gastrodia elata, Senecio, Guizhi, Licorice, Bingtangcao, Hibiscus leaves and Aescin aesculus mixed with medicinal materials, rinsed with water, dried, crushed, added 8 times the amount of water, soaked for 1 hour, decocted Boil for 2 hours, filter the medicinal liquid, and use the filtrate for later use. Under the same conditions, decoct the medicinal residues three times, combine the filtrate, and concentrate under reduced pressure to a small volume to obtain a concentrated liquid of the mixed medicinal material extract;

[0038] 2) remove the outer skin of fre...

Embodiment 2

[0041] A medicine for treating postherpetic neuralgia, the medicine is made of the following raw materials in weight ratio:

[0042]

[0043] The preparation method is as follows:

[0044] 1) Dipsacus, Pangui, Notoginseng, Chuanxiong, Turmeric, Cardamom, Frankincense, Myrrh, Curcuma, Woody Fragrance, Liu Jinu, Duhuo, Schizonepeta, Clematis, Paeoniae Alba, Amaranth, Red Flower, Amomum, Imperatae Rhizome, Gastrodia elata, Senecio, Guizhi, Licorice, Bingtangcao, hibiscus leaves and Aescin aesculus mixed with medicinal materials, rinsed with water, dried, crushed, added 10 times the amount of water, soaked for 1 hour, decocted Boil for 3 hours, filter the medicinal liquid, and use the filtrate for later use. Repeat decocting the medicinal residue twice under the same conditions, combine the filtrate, and concentrate under reduced pressure to a small volume to obtain a concentrated liquid of the mixed medicinal material extract;

[0045] 2) Remove the outer skin of fresh garlic...

Embodiment 3

[0048] A medicine for treating postherpetic neuralgia, the medicine is made of the following raw materials in weight ratio:

[0049]

[0050] The preparation method is as follows:

[0051] 1) Dipsacus, Pangui, Notoginseng, Chuanxiong, Turmeric, Cardamom, Frankincense, Myrrh, Curcuma, Woody Fragrance, Liu Jinu, Duhuo, Schizonepeta, Clematis, Paeoniae Alba, Amaranth, Red Flower, Amomum, Imperatae Rhizome, Gastrodia elata, Senecio, Guizhi, Licorice, Bingtangcao, Hibiscus leaves and Aesculus aesculus mixed with medicinal materials, rinsed with water, dried, crushed, added 12 times the amount of water, soaked for 1 hour, decocted Boil for 1 hour, filter the medicinal liquid, and use the filtrate for later use. Repeat decocting the medicinal residue twice under the same conditions, combine the filtrate, and concentrate under reduced pressure to a small volume to obtain a concentrated liquid of the mixed medicinal material extract;

[0052] 2) Remove the outer skin of fresh garli...

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PUM

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Abstract

The invention relates to the fields of medicines and pharmacology, in particular to a medicine for treating postherpetic neuralgia and a preparation method of the medicine. On the basis of the theory of traditional Chinese medicine and the latest pharmaceutical research achievement and through the utilization of modern technological means, the medicine is prepared into an oral preparation, preferably into capsules, tablets and granules, from radix dipsaci, herba polygoni perfoliati, panax notoginseng, garlic, rhizoma ligustici wallichii, rhizoma curcumae longae, katsumade galangal seed, radix aucklandiae, diverse wormwood herb, amaranthus viridis, flos carthami, fructus amomi, lalang grass rhizome, sweet broomwort herb, folium hibisci, rhizoma paridis and the like. Pharmacodynamic experiment researches show that the medicine provided by the invention has an ideal inhibitory effect on PHN, and the medicine provided by the invention is convenient to use, good in safety and free from drug dependency; the medicine, which is completely prepared from natural medicinal herbs, is free from any chemical additives, and the medicine, when taken for a long time, is safe and reliable; the tolerance and the compliance of patients can be improved to a great extent, so that a novel optional scheme is provided for the long-term treatment of the patients with the PHN; and the medicine can meet current clinical demands.

Description

technical field [0001] The invention relates to the fields of medicine and pharmacy, in particular to a medicine for treating postherpetic neuralgia and a preparation method thereof. Background technique [0002] Herpes zoster is an acute infectious skin disease caused by varicella-zoster virus (VZV). Herpes zoster virus is a neurotropic herpes virus that usually invades sensory neurons when patients are infected with chickenpox in childhood, and some patients become virus carriers without symptoms after being infected. Because the virus is neurotropic, it can remain dormant in the neurons of the dorsal root ganglia of the spinal cord for a long time after infection. When the resistance is low or when you are tired, infected, or caught a cold, the virus can grow and multiply again, and move to the skin along the nerve fibers , causing intense inflammation to the affected nerves and skin, the resulting rash is generally unilateral and distributed according to nerve segments,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P31/22A61P25/02
CPCA61K36/9066A61K9/1605A61K9/2004A61K36/11A61K36/185A61K36/21A61K36/232A61K36/236A61K36/258A61K36/28A61K36/282A61K36/285A61K36/286A61K36/324A61K36/328A61K36/484A61K36/538A61K36/54A61K36/65A61K36/70A61K36/71A61K36/716A61K36/80A61K36/896A61K36/8962A61K36/8988A61K36/899A61K36/9062A61K36/9064A61K2236/31A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 傅天锡
Owner 傅天锡
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