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Medicinal and edible composition for hepatic disease with malnutrition, as well as preparation and preparation application of medicinal and edible composition

A malnutrition and composition technology, applied in the fields of pharmaceutical compositions and traditional Chinese medicine compositions, achieves the effects of good safety, good taste and low price

Inactive Publication Date: 2017-05-31
BEIJING YOUAN HOSPITAL CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The main technical problem to be solved by the present invention is how to simultaneously supplement nutrients and improve liver function and digestion and absorption function

Method used

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  • Medicinal and edible composition for hepatic disease with malnutrition, as well as preparation and preparation application of medicinal and edible composition
  • Medicinal and edible composition for hepatic disease with malnutrition, as well as preparation and preparation application of medicinal and edible composition
  • Medicinal and edible composition for hepatic disease with malnutrition, as well as preparation and preparation application of medicinal and edible composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Preparation method: Calculated in parts by weight, weigh 15g of wolfberry, 15g of yam, 15g of hawthorn, 15g of malt and 9g of raisin seed, and soak the medicine in cold water for about 20 minutes before decocting, which is conducive to the precipitation of active ingredients of the medicine. After adding water, the traditional Chinese medicine is completely immersed in the water. The water surface should be 2-3cm higher than the traditional Chinese medicine. The decoction should be boiled in high heat first, and then boiled in a slow fire. Each dose should be decocted twice. The first decoction time is 30 minutes after boiling. The amount of boiling water used for the second time is less than that of the first time, and the time for frying is 40 minutes after boiling. Take 200 ml of medicinal juice for each of the two times, a total of 400 ml, mix well, and set aside. The final prepared medicinal liquid is 69g of traditional Chinese medicine composition corresponding to ...

Embodiment 2

[0060] Example 2 Establishment of Rat Liver Cirrhosis Model

[0061] 1. Materials

[0062] 1.1 Experimental animals

[0063]SPF grade healthy SD rats, male, 4-6 weeks old, body weight 180±20g / rat, 30 in total. Provided by Beijing Military Research Institute, they were bred in the animal room of Beijing Institute of Liver Diseases. All animals were adaptively fed with common feed for one week before the experiment. All the feed, drinking water and bedding meet the clean standard, the environment is clean and quiet, the temperature is controlled at 26±2°C, and the humidity is controlled at 60±10%.

[0064] 1.2 Main reagents

[0065] Carbon tetrachloride Sinopharm Chemical Reagent Co., Ltd.

[0066] Olive Oil Beijing Huayuan Life Science and Trade Development Co., Ltd.

[0067] 1.3 Instruments and equipment

[0068]

[0069]

[0070] 2. Method

[0071] 2.1 Preparation of carbon tetrachloride oil solution

[0072] Carbon tetrachloride (CCl 4 ) and olive oil are con...

Embodiment 3

[0093] Embodiment three animal experiment

[0094] On the basis of the successful modeling, the influence of the traditional Chinese medicine formula of the present invention on the amino acid level and the general growth state of the liver cirrhosis rat model was further studied. Among them, the specific experimental process and experimental results are as follows:

[0095] 1. Materials

[0096] 1.1 Experimental animals

[0097] SPF grade healthy SD rats, male, 4-6 weeks old, body weight 180±20g / rat, 37 in total. Provided by Beijing Military Research Institute, they were bred in the animal room of Beijing Institute of Liver Diseases. All animals were adaptively fed with common feed for one week before the experiment. All the feed, drinking water and bedding meet the clean standard, the environment is clean and quiet, the temperature is controlled at 26±2°C, and the humidity is controlled at 60±10%.

[0098] 1.2 Drugs and reagents

[0099] Carbon tetrachloride (Sinopharm...

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Abstract

The invention belongs to the field of medicine compositions and particularly relates to a medicinal and edible composition for treating a hepatic disease with malnutrition, a preparation and a preparation application. The composition comprises the following ingredients: Chinese wolfberries, Chinese yams, hawthorns, malt and semen raphani. The traditional Chinese medicine preparation comprises the medicinal and edible composition as an active ingredient and an auxiliary material. A reagent kit comprises traditional Chinese medicine preparation reagent units, wherein an effective dose of the medicinal and edible composition of each reagent unit is 0.1-3g. The invention further provides the application of the medicinal and edible composition or the traditional Chinese medicine preparation or the reagent kit in the field of preparing a medicine for treating the hepatic disease with the malnutrition or the field of preparing a health care product or food for protecting a liver. The medicinal and edible composition has multiple effects of supplementing nutrients, improving a liver function, improving an appetite and relieving abdominal distention, is good in safety and taste and low in price, and has obvious advantages in nutritional supplementation for a patient with the hepatic disease.

Description

technical field [0001] The invention belongs to the field of pharmaceutical compositions, in particular to the field of traditional Chinese medicine pharmaceutical compositions, in particular to a medicinal-food composition for treating liver disease complicated with malnutrition, its preparation and preparation application. Background technique [0002] Malnutrition is common in patients with liver disease, especially in severe patients such as liver cirrhosis and liver cancer, the incidence of malnutrition is extremely high. The malnutrition problem of liver disease patients has been highly valued by the industry in recent years, and the harmfulness of malnutrition and the importance of nutritional intervention are highly valued. The liver has extremely complex functions and is the central organ of sugar, fat and protein metabolism. Taking liver cirrhosis as an example, due to abnormal liver structure and function changes, various metabolic pathways related to it have dif...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P1/16A61P1/14A61K35/57
CPCA61K36/815A61K9/0095A61K35/57A61K36/31A61K36/734A61K36/8945A61K36/8969A61K36/8998A61K47/24A61K47/36A61K47/40A61K47/42A61K47/46A61K2236/331A61K2236/53A61K2300/00
Inventor 杨华升杨薇李秀惠许文君路宽
Owner BEIJING YOUAN HOSPITAL CAPITAL MEDICAL UNIV
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