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Menoxenia prevention and treatment traditional Chinese medicine composition preparation method

A technology of irregular menstruation and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc. It can solve the problems of difficulty in making tablets with low excipients, difficulty in uniform particle density and size, long heating time, etc. problems, to achieve the effect of shortening the heating time, guaranteeing the quality control of finished products, and long production time

Inactive Publication Date: 2017-06-16
韩丰河
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AI Technical Summary

Problems solved by technology

The preparation method disclosed above adopts the wet granulation method, and the Chinese medicine extract needs to be concentrated into a thick extract, which is heated for a long time, and the resulting granules are generally darker in color, and the density and size of the granules are not uniform. Process tablet production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Boil 24g of Motherwort, 12g of Rhizoma Cyperi, 12g of Passepartout, 12g of Rhizoma Chuanxiong, 12g of Wangbuliuxing, and 12g of Caulis Spatholobus with water for 2 extractions. The amount of water added for the first extraction is 10 times the amount of medicine, and the extraction time is 2 hours. The amount of water added for the second time is 7 times the amount of medicine, and the extraction time is 2 hours; filter, combine the filtrate, and concentrate into a water-extracted dilute extract with a relative density of 1.05; put dextrin or starch, etc. in a one-step granulator As a substrate, spray the above water-extracted extract as a binder into a one-step granulator, open the air inlet and outlet, control the negative pressure of -0.02MPa to make the powder boil evenly in the granulator tank, and then heat to control the material The temperature is 30°C, one-step granulation is carried out, and the granulation time is 5 hours; the granules produced by the one-step...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition for preventing and treating irregular menstruation. Water extraction and concentration into water extraction dilute extract, or use water extraction and alcohol precipitation to concentrate into water extraction and alcohol precipitation dilute extract; then, put dextrin or starch in a one-step granulator as a substrate, and dilute the above water The extract or water-extracted and alcohol-settled extract is used as a binder and sprayed into a one-step granulator for one-step granulation; finally, the granules are sized, and other auxiliary materials are added to make a traditional Chinese medicine oral preparation. The method can significantly reduce the amount of auxiliary materials, shorten the processing time and the heating time for concentration and drying, avoid destroying the active ingredients of the traditional Chinese medicine composition, the produced granules have good fluidity, the compressed tablets disintegrate faster, and the process flow is simplified , reduces energy consumption, the production process is not easy to be polluted, and the quality of finished products is better guaranteed.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition, in particular to a traditional Chinese medicine combination for preventing and treating irregular menstruation [0002] method of preparation. Background technique [0003] Gynecological diseases--Irregular menstruation refers to the abnormality of menstrual cycle, menstrual period, menstrual volume, menstrual color, and menstrual quality, or it is accompanied by menstrual cycle [0004] Symptoms are characterized by gynecological diseases, including premenstrual period, late period, irregular menstruation, menorrhagia, dysmenorrhea, etc., as well as systemic symptoms such as headache, insomnia, and diarrhea caused by irregular menstruation. [0005] According to the survey and statistics of the Ministry of Health, the incidence rate of gynecological diseases in my country is as high as 75%, among which patients with irregular menstruation and dysmenorrhea are...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P15/00
CPCA61K36/8905A61K9/2059A61K36/185A61K36/236A61K36/36A61K36/486A61K36/533A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 韩丰河
Owner 韩丰河
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