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Production method of hypochloric acid solution and medical clinical application of the solution

A hypochlorous acid solution and its production method are applied in skin care preparations, pharmaceutical formulations, chlorine active ingredients, etc., which can solve problems such as limited application range and instability, and achieve the effect of promoting ulcer healing

Inactive Publication Date: 2017-07-14
黄坚文
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  • Application Information

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Problems solved by technology

[0003] The present invention provides a preparation method of hypochlorous acid solution and its medical clinical application, to solve the problem that its acidity and instability lead to the limitation of application range

Method used

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Embodiment Construction

[0016] The preparation method of hypochlorous acid solution provided by the invention is as follows:

[0017] A. Add reaction solution in an electrochemical device, that is, NaCl solution 20-40g / L, pH 1-2, the solution produced by the reaction contains hypochlorous acid, that is, the solubility of HOCl is 100ppm-150ppm, and the pH of the solution is 3.5-4.5 , the oxidation potential value ORP is between 800mV and 1200mV;

[0018] B. Add Na 2 HPO 4 2H 2 O 0.10%~0.15%, KH 2 PO 4 8.00-10.00%, keep the pH value of the solution between 4.9-5.2, and fill it into a glass bottle.

[0019] The chemical formula of the above method:

[0020] Packaged in a closed brown medicinal bottle at room temperature, its available chlorine content will remain at 80-95% of its original concentration after 2 years. The packaging bottle was opened and sucked out 1ml with a pipette, and then the packaging bottle was tightly closed, and repeated 3 times. After two weeks, the changes of the HOCl ...

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Abstract

The invention discloses a production method of a hypochloric acid solution and medical clinical applications of the solution. The production method comprises the following steps: 1) adding a reaction solution to an electrochemical device, namely, 20-40 g / L of a NaCl solution, pH being 1-2, to carry out a reaction to produce a solution which contains hypochloric acid, concentration of HClO being 100-150 ppm, pH of the solution being 3.5-4.5 and oxidation potential value (ORP) being 800-1200 mV; and 2) adding 0.10-0.15% of Na2HPO4.2H2O and 8.00-10.00% of KH2PO4 to maintain the pH value of the solution to be 4.9-5.2 and filling a glass bottle with the produced solution. The solution is a stable and approximately neutral HClO solution and has the functions of quickly killing bacteria, fungi, spores and viruses; by means of the functions, the HClO solution can be applied for cleaning and disinfecting surface wounds and ulcers of human body without toxicity and irritation on skin, mucosa and conjunctiva.

Description

technical field [0001] The invention relates to a chemical solution and its application, in particular to a preparation method of a hypochlorous acid (HOCl) solution and its medical clinical application. Background technique [0002] Hypochlorous acid is an endogenous substance in the human body. When an inflammatory response occurs, it is secreted by neutrophils to kill pathogenic bacteria that invade the body. Electrochemical method can be used to electrolyze NaCl solution to produce a mixed solution of NaOCl and HOCl. This solution has strong sterilizing properties, but its acidity (pH 1-2) and instability (validity period 1-2 hours) are limited. It can only be used for disinfection of corrosion-resistant appliances or environmental disinfection. Contents of the invention [0003] The invention provides a preparation method of a hypochlorous acid solution and its medical clinical application, and the problem that the acidity and instability of the hypochlorous acid sol...

Claims

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Application Information

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IPC IPC(8): A61K33/20A61P31/12A61P31/04A61P31/10A61P17/02A61K8/20A61Q19/10C25B1/26
CPCA61K33/20A61K8/20A61Q19/10C25B1/26
Inventor 黄坚文
Owner 黄坚文
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