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Medicinal silybum marianum cultivation technique and method for extracting silymarin

A technology for silymarin and silymarin, which is applied in the fields of medicinal silymarin cultivation and silymarin extraction, can solve the problems that the medicinal value of silymarin cannot meet the development needs of the medical market, the yield of silymarin is low, the medicinal value is reduced, and the like, and achieves enhanced Drug effect and finished product quality, avoid prolonged heating time, and the effect of plump particles

Inactive Publication Date: 2017-08-25
四川利君精华制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The quality of milk thistle seeds is directly related to the yield and medical value of milk thistle extract. The existing milk thistle planting technology has low yield and poor quality, low yield of silymarin, and greatly reduced medicinal value, making silymarin The medicinal value is far from meeting the development needs of the medical market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] A medicinal milk thistle cultivation technique, comprising the following steps:

[0056] (1) Site selection

[0057] Select slightly acidic sandy loam with deep soil layer, loose soil, fertile soil, good drainage, sunny and dry, and rake it repeatedly;

[0058] (2) Soil treatment

[0059] Apply base fertilizer before sowing, apply base fertilizer 1500 kg per mu, superphosphate 45 kg, tillage depth 24 cm, rake fine leveling ridges, ridge width 1.8 m, ridge spacing 40 cm, plant 3 rows per ridge, apply 7 kg per mu 3% Miller granules, mixed with 40kg of fine dry soil, evenly removed on the surface, raked 20cm deep, and then planted after shallow covering soil;

[0060] (3) Seed treatment

[0061] When sowing with seeds, take the stored seeds and wrap them in gauze, soak them in warm water at 25°C for 2 hours; disinfect the seeds: soak them in 2000 times carbendazim solution for 12 hours, then wash the seeds with clean water; Soak in the initiator solution for 8 hours, t...

Embodiment 2

[0079] A medicinal milk thistle cultivation technique, comprising the following steps:

[0080] (1) Site selection

[0081] Select slightly acidic sandy loam with deep soil layer, loose soil, fertile soil, good drainage, sunny and dry, and rake it repeatedly;

[0082] (2) Soil treatment

[0083] Apply base fertilizer before sowing, base fertilizer 2000 kg per mu, superphosphate 60 kg, plowing depth 32 cm, rake fine leveling ridges, ridge width 1.8 m, ridge spacing 40 cm, plant 3 rows per ridge, apply 10 kg per mu 3% Miller granules, mixed with 50kg of fine dry soil, evenly removed on the surface, raked 20cm deep, and then planted after shallow covering of soil;

[0084] (3) Seed treatment

[0085]When sowing with seeds, take the stored seeds and wrap them in gauze, soak them in warm water at 25°C for 2 hours; disinfect the seeds: soak them in 2000 times carbendazim solution for 12 hours, then wash the seeds with clean water; Put it in the initiator solution and soak for 16...

Embodiment 3

[0103] A medicinal milk thistle cultivation technique, comprising the following steps:

[0104] (1) Site selection

[0105] Select slightly acidic sandy loam with deep soil layer, loose soil, fertile soil, good drainage, sunny and dry, and rake it repeatedly;

[0106] (2) Soil treatment

[0107] Apply base fertilizer before sowing, base fertilizer 2000 kg per mu, superphosphate 60 kg, plowing depth 32 cm, rake fine leveling ridges, ridge width 1.8 m, ridge spacing 40 cm, plant 3 rows per ridge, apply 10 kg per mu 3% Miller granules, mixed with 50kg of fine dry soil, evenly removed on the surface, raked 20cm deep, and then planted after shallow covering of soil;

[0108] (3) Seed treatment

[0109] When sowing with seeds, take the stored seeds and wrap them in gauze, soak them in warm water at 25°C for 2 hours; disinfect the seeds: soak them in 2000 times carbendazim solution for 12 hours, then wash the seeds with clean water; Put it in the initiator solution and soak for 1...

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Abstract

The invention provides a medicinal silybum marianum cultivation technique and a method for extracting silymarin. The scientific technology and the modern precision management are adopted, the high yield and large-scale cultivation of the medicinal silybum marianum are achieved, the alkaline alcoholic pyrolysis technology and the ethyl acetate extraction technology are adopted, and high yield and high purity of the silybum marianum are achieved. Compared with the prior art, the technique and method achieve the high-yield and precise planting management of the silybum marianum, improve the yield and medical quality of the silymarin, maximize the medicinal value of the silymarin and meet the requirement of a medical market for the silymarin.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicinal materials, in particular to a medicinal milk thistle cultivation technique and a method for extracting silymarin. Background technique [0002] Milk thistle is a herbal medicinal plant of Compositae, also known as Shuifeidui and Mousele. Milk thistle seeds are processed to extract silymarin and silymarin, which can improve liver function and protect liver cells. It is a medicinal plant for protecting the liver and has special curative effects for treating acute and chronic hepatitis, cirrhosis and other liver diseases. At the same time, silymarin, the secondary product obtained after deep processing of milk thistle seeds, has the effects of "five resistances and one reduction", that is, anti-free radical activity, anti-lipid peroxidation, anti-lipoxygenase, anti-" GSH" emptying, anti-tumor and hypolipidemic effects. The quality of milk thistle seeds is directly related to t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01G1/00A01C1/00A01C1/08C07D407/04
CPCA01C1/00A01C1/08A01G22/00C07D407/04
Inventor 韩国英杨发胜王锋怀潘建明岳元
Owner 四川利君精华制药股份有限公司
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