Method for treating malignant tumors by using nickase

A cancer tumor cutting enzyme technology, applied in the medical field, can solve problems such as the magnetic field space that has not yet been developed, and achieve the effect of small side effects

Inactive Publication Date: 2017-11-03
THE FIRST AFFILIATED HOSPITAL OF NANYANG MEDICAL JUNIOR COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most research units are conducting research around low-energy local stable magnetic fields, and have not yet developed a ...

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0013] The present invention is a method for treating cancer tumors by using cleavage enzyme to treat cancer tumor cells. The treatment method is one of the three physical methods of magnetic field, microwave or ultrasonic wave. The treatment time is 1 week, and the magnetic field, Microwave or ultrasound, these three physical methods can be used alone or in combination, and the treatment cycle is 1 week, so that the cancer tumor cell tissue becomes like an early cancer tumor, and forms a capsule outside it, and then proceeds Resection, after surgical resection, the tumor samples obtained from the early cancer tumors are collected and sequenced, and then the endonuclease recognition sequence is calculated and located to complete the design of the endonuclease, and the modified and detoxified virus is used as a carrier delivery tool To deliver the designed cleavage enzyme, local injection can be used to deliver the lesion. The endonuclease enters the body by transporting in vivo...

Embodiment 2

[0015] The present invention is a method for treating cancer tumors by using cleavage enzymes to treat cancer tumor cells. The treatment method is one of the three physical methods of magnetic field, microwave or ultrasonic wave. The treatment time is 2 weeks, and the magnetic field, Microwave or ultrasound, these three physical methods can be used alone or in combination, and the treatment cycle is 3 weeks, so that the cancer tumor cell tissue becomes like an early cancer tumor, and forms a capsule outside it, and then proceeds Resection, after surgical resection, the tumor samples obtained from the early cancer tumors are collected and sequenced, and then the endonuclease recognition sequence is calculated and located to complete the design of the endonuclease, and the modified and detoxified virus is used as a carrier delivery tool To deliver the designed cleavage enzyme, local injection can be used to deliver the lesion. The endonuclease enters the body by transporting in v...

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PUM

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Abstract

The invention discloses a method for treating malignant tumors by using nickase, belonging to the field of medical technology. According to the invention, malignant tumor cells are treated so as to allow malignant tumor cell tissue to resemble an early-stage malignant tumor; an envelope is formed out of the malignant tumor cell resembling the early-stage malignant tumor, and excision is carried out; and after excision, a tumor sample acquired from the early-stage malignant tumor is subjected to acquisition of malignant tumor cells for sequencing, followed-up calculation and positioning of the recognition sequence of endonuclease so as to complete designing of endonuclease; and the endonuclease enters a body via an in-vivo delivery tool such as a deactivated virus and cleaves malignant tumor promoter at a certain site and sequences at other sites. The method provided by the invention poses no harm to normal cells while killing cancer cells, has little side effect and can realize fixed-point elimination.

Description

technical field [0001] The invention specifically relates to a method for treating cancer tumors by using cleavage enzyme, which belongs to the field of medical technology. Background technique [0002] Tumor is a major disease that threatens human health and life safety, and kills many people every year. The research and development of anti-tumor treatment schemes has always been a hot spot for chemists and pharmacologists. Finding harmless and effective treatment schemes is a key issue in the field of tumors. research topic. There have been some reports on the inhibitory effect of magnetic energy on tumor growth. The principle is to improve the body's own immunity by regulating the functions of the human body through the magnetic force, and to inhibit and kill tumors through the body's own immunity. As we all know, the changing magnetic field has a greater accelerating adjustment effect on the charged body than the uniform magnetic field. At present, most research units ...

Claims

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Application Information

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IPC IPC(8): A61K38/46A61P35/00
CPCA61K38/46
Inventor 黄国胜黄普李汉智亚国伟王虔
Owner THE FIRST AFFILIATED HOSPITAL OF NANYANG MEDICAL JUNIOR COLLEGE
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