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Preparation method of rheumatic plaster for treating lumbar postoperative lumbago and backache

A technology for low back pain and rheumatism, applied in the field of medical supplies, can solve the problems of local skin irritation, irritating odor, redness and swelling, etc., achieve good skin comfort, speed up metabolism, and reduce inflammation

Inactive Publication Date: 2018-01-26
NANJING XIANCAOTANG BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The use of external patches has a long history, and there are many inconveniences in the application process of traditional external patches, such as local skin irritation, allergies, redness, irritating odor, etc.

Method used

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  • Preparation method of rheumatic plaster for treating lumbar postoperative lumbago and backache
  • Preparation method of rheumatic plaster for treating lumbar postoperative lumbago and backache
  • Preparation method of rheumatic plaster for treating lumbar postoperative lumbago and backache

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: A kind of preparation method of rheumatism plaster for the treatment of lumbar postoperative low back pain

[0033] A rheumatism plaster for treating low back pain after lumbar spine surgery. In parts by weight, the raw material formula of the rheumatism plaster for treating low back pain after lumbar spine surgery includes: 35 parts of centipede, 23 parts of Cortex Phellodendri, 18 parts of Salvia miltiorrhiza, and 15 parts of angelica , 12 parts of Raw Aconiti, 8 parts of Polygonum cuspidatum, 5 parts of safflower, 8 parts of papaya, 7 parts of Duhuo, 3 parts of Caulis Spatholobus, 30 parts of sesame oil, 12 parts of glycerin, 15 parts of adhesive, and 12 parts of dissolving agent.

[0034] The adhesive is a copolymer of 2-ethylhexyl methacrylate monomer and 2-ethylhexyl acrylate monomer. .

[0035] The solvent is octyldodecanol.

[0036] The preparation method comprises the following steps:

[0037] (1) Take fresh and live centipede adults, quickly p...

Embodiment 2

[0043] Embodiment 2: A kind of preparation method of rheumatism plaster for the treatment of lumbar postoperative low back pain

[0044] A rheumatism plaster for treating low back pain after lumbar spine surgery. In parts by weight, the raw material formula of the rheumatism plaster for treating low back pain after lumbar spine surgery includes: 50 parts of centipede, 38 parts of Cortex Phellodendri, 40 parts of Salvia miltiorrhiza, and 30 parts of angelica , 26 parts of Raw Aconiti, 14 parts of Polygonum cuspidatum, 16 parts of safflower, 12 parts of papaya, 15 parts of lovage, 13 parts of Caulis Spatholobus, 55 parts of sesame oil, 28 parts of glycerin, 25 parts of adhesive, and 22 parts of solvent.

[0045] The adhesive is a copolymer of 2-ethylhexyl methacrylate monomer and 2-ethylhexyl acrylate monomer. The preparation method may be as follows: weighing a certain amount of sodium oleate into a 250mL three-necked bottle equipped with a liquid seal, a stirrer, and a reflux ...

Embodiment 3

[0054] Embodiment 3: A kind of preparation method of rheumatism plaster for the treatment of lumbar postoperative low back pain

[0055] A rheumatism plaster for treating low back pain after lumbar spine surgery. In parts by weight, the raw material formula of the rheumatism plaster for treating low back pain after lumbar spine surgery includes: 58 parts of centipede, 46 parts of Cortex Phellodendri, 45 parts of Danshen, and 35 parts of angelica , 30 parts of Raw Aconiti, 19 parts of Polygonum cuspidatum, 22 parts of safflower, 15 parts of papaya, 21 parts of lovage, 17 parts of Caulis Spatholobus, 65 parts of sesame oil, 35 parts of glycerin, 30 parts of adhesive, and 28 parts of solvent.

[0056] The adhesive is a copolymer of 2-ethylhexyl methacrylate monomer and 2-ethylhexyl acrylate monomer.

[0057] The solvent is octyldodecanol.

[0058] The preparation method comprises the following steps:

[0059] (1) Take fresh and live centipede adults, put them in a liquid nitrog...

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Abstract

The invention discloses a preparation method of a rheumatic plaster for treating lumbar postoperative lumbago and backache. The preparation method comprises the following steps: freezing fresh and alive adult centipedes by liquid nitrogen, grinding the centipedes into powder, pouring the powder into a centrifuge tube, and adding an aqueous solution of ammonium sulfate and an aqueous solution of protease K; boiling the centrifuge tube for 2-8 minutes, cooling on ice, shaking, and centrifuging to take the supernatant; adding absolute ethyl alcohol into the supernatant, uniformly mixing, centrifuging to take the upper protein fluid, and performing freeze drying to prepare freeze-dried powder; taking cortex phellodendri, salvia miltiorrhiza, angelica sinensis, radix aconiti kusenzoffii, polygonum cuspidatum, safflower, pawpaw, radix angelicae pubescentis and caulis spatholobi, milling, adding the powder into water and soaking, decocting with water, and filtering to obtain the filtrate; adding sesame oil and glycerin into the filtrate, and boiling to be in a boiling state so as to obtain clear paste; and completely dissolving the freeze-dried powder, the clear paste, a solvent and an adhesive into ethyl acetate, coating onto released paper, thereby obtaining the rheumatic plaster. The plaster prepared by the invention does not have any adverse reaction, and the skin comfort level ishigh.

Description

technical field [0001] The invention relates to a plaster, in particular to a preparation method of a rheumatism plaster for treating low back pain after lumbar spine surgery, and belongs to the technical field of medical supplies. Background technique [0002] Lumbar back pain after lumbar surgery is one of the most common symptoms after spinal surgery. It is mostly caused by surgical trauma, local inflammatory stimulation, soft tissue swelling, nerve edema and other factors, which prolongs the patient's bed rest time and increases postoperative lower extremity thrombosis and Risk of bedridden complications. At present, oral non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors are often used as adjuvant therapy in clinical practice. However, due to the gastrointestinal and cardiovascular risks of these drugs, the blood drug concentration after repeated oral administration Difficulty stabilizing leads to poor clinical effect. [0003] At present, many dome...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/70A61P19/00A61P29/00A61K35/648
Inventor 史月龙曾宋君吴英亮刘文斌吴坤林汤静
Owner NANJING XIANCAOTANG BIOLOGICAL TECH CO LTD
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