A kind of traditional Chinese medicine composition, pharmaceutical preparation and application thereof

A technology for pharmaceutical preparations and compositions, applied in the field of traditional Chinese medicine, can solve the problems of inability to obtain satisfactory bacteriostatic and bactericidal effects, low bactericidal rate, no hemostasis, swelling reduction, convergence and the like

Active Publication Date: 2020-10-30
清远市豪久药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, studies have also found that the bactericidal rate of existing externally-used traditional Chinese medicine bactericides is not high, and satisfactory bacteriostatic and bactericidal effects cannot be obtained, which can easily lead to wound infection
Moreover, the existing externally-used traditional Chinese medicine fungicides have no hemostatic, detumescent, and astringent effects, and have no positive effect on wound healing, so they cannot be used alone as wound healing drugs.

Method used

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  • A kind of traditional Chinese medicine composition, pharmaceutical preparation and application thereof
  • A kind of traditional Chinese medicine composition, pharmaceutical preparation and application thereof
  • A kind of traditional Chinese medicine composition, pharmaceutical preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] A stainless steel pulverizer is used to crush the medicinal materials of Baibu and Burnet into particles with a particle size of 2-5 mm. Add 5g of burnet and 5g of burnet in granular form to 205g of 80% (w / w) ethanol solution and soak at room temperature for 25 days, then use a plate and frame filter press for coarse filtration, and then let the filtrate stand for precipitation at room temperature On day 7, take the supernatant as pharmaceutical preparation A.

Embodiment 2

[0078] A stainless steel pulverizer is used to crush the medicinal materials of Baibu, Burnet and Sophora flavescens into particles with a particle size of 2-5 mm. Join the 80% (w / w) ethanol solution of 205g granule 5g burnet, 5g Burnet and 3g Kushen to soak at normal temperature for 25 days, then use a plate and frame filter press for rough filtration, and then filter the filtrate at normal temperature After standing still for 7 days, the supernatant was taken as pharmaceutical preparation B.

Embodiment 3

[0080] A stainless steel pulverizer is used to crush the medicinal materials of Baibu, Burnet, Kochia, Sophora flavescens, Zanthoxylum bungeanum, and dried blood into particles with a particle size of 2-5 mm. Add granular 5g of 100bu, 5g of Burnet, 5g of Kochia, 3g of flavescens, 2g of Zanthoxylum bungeanum and 0.5g of dried blood to 205g of 80% (w / w) ethanol solution and soak at room temperature for 25 days, and then use a plate Rough filtration with a frame filter press, and then the filtrate was left to settle at room temperature for 7 days, and the supernatant was taken as pharmaceutical preparation C.

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Abstract

The invention belongs to the field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition. The traditional Chinese medicine composition contains the following components: 8-29 parts of radix stemonae and 6-31 parts of radix sanguisorbae. The invention further relates to a medicine preparation. The traditional Chinese medicine composition is capableof killing bacteria (escherichia coli and staphylococcus aureus) and / or fungus (Candida albicans). The components of the traditional Chinese medicine composition can generate a synergetic sterilizingeffect; and furthermore, the traditional Chinese medicine composition has the efficacies of stopping bleeding, diminishing swelling and astringing and healing wounds.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition, and also relates to a medicinal preparation and the application of the traditional Chinese medicinal composition or medicinal preparation in killing bacteria and / or fungi. Background technique [0002] The topical fungicides sold on the market today are mainly chemical preparations, such as alcohol disinfectants, povidone iodine and povidone-iodine disinfectants. Although the product maturity of chemical preparation fungicides is high, there are also many shortcomings; for example, iodophor is easy to sublime and lose when it is above 30°C, and the bactericidal effect of iodophor is weakened in an alkaline environment, and contact with organic matter will also cause iodophor Bactericidal rate reduces; The viscosity of povidone-iodine is big, is inconvenient to operate and use, and, the stability of povidone-iodine...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A61K36/904A61P31/02A61P31/04A61P31/10A61P17/02A61P7/04A61P29/00
CPCA61K36/185A61K36/489A61K36/739A61K36/758A61K36/889A61K36/896A61K36/904A61K2236/15A61K2236/33A61K2236/333A61K2236/53A61K2300/00Y02A50/30
Inventor吴镜深
Owner清远市豪久药业有限责任公司