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Automatic brain probe guidance system

A detector and brain technology, applied in the field of automatic brain-detector guidance system, can solve the problem that the symptoms of patients cannot be fully controlled by drugs

Active Publication Date: 2018-03-27
阿尔法欧米伽医疗科技公司
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  • Abstract
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  • Claims
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Problems solved by technology

Currently, the procedure is only used in patients whose symptoms are not adequately controlled with medication

Method used

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  • Automatic brain probe guidance system
  • Automatic brain probe guidance system
  • Automatic brain probe guidance system

Examples

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Embodiment Construction

[0018] The present application relates to an automated brain detector guidance system in one embodiment.

[0019] The present application provides an automated guidance system for guiding a detector (eg, MER) to a target region in the brain for the treatment of a Parkinson's disease. Surgery for advanced Parkinson's disease (PD) includes deep brain stimulation (DBS) of the subthalamic nucleus (STN), which has been shown to be safe and beneficial over time. Microelectrode recording (MER) is often used to physiologically verify the localization of the subthalamic nucleus during surgery to implant a thick electrode for deep brain stimulation of the subthalamic nucleus. In order to successfully implant the coarse electrode at the optimal location (possibly part of the subthalamic nucleus sensoridriver), the patient's subthalamic nucleus needs to be accurately defined (based on the number of microelectrode recordings). ). This involved deriving the entry and exit points of the su...

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Abstract

The disclosure relates to an automatic brain-probe guidance systems. Specifically, the disclosure is directed to a real-time method and system for guiding a probe to the dorsolateral oscillatory region of the subthalamic nucleus in the brain of a subject in need thereof using factored Partially Observable Markov Decision Process (POMDP) via Hidden Markov Model (HMM) represented as a dynamic Bayesian Network (DBN).

Description

[0001] Cross-Referenced Related Applications [0002] This application claims priority to US Provisional Patent Application Serial No. 62 / 159,336, filed May 10, 2015, the entire contents of which are hereby incorporated by reference. technical field [0003] This application is about an automatic brain-detector guidance system. Specifically, the present application relates to a real-time method and system for directing a probe to the dorsoparalateral oscillation region of the subthalamic nucleus in the brain of a subject in need thereof, using closed stochastic electrophysiological feedback. Background technique [0004] Deep Brain Stimulation (DBS) is a procedure involving the implantation of a medical device called a coarse electrode (also called a "pin," "brain pacemaker," "electrode," or "chronic electrode"). A surgical procedure that sends electrical impulses to specific parts of the brain. Selective deep brain stimulation of multiple regions within the brain provid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/04A61B5/0476A61N1/00A61N1/05A61N1/36G06F3/01A61B5/375
CPCA61N1/0534A61B90/11A61B2017/3409A61B2017/00022A61B5/375G06F18/295A61B5/293A61B34/20
Inventor 马基德·米歇尔丹·瓦尔斯基哈加伊·伯格曼兹维·伊斯雷尔
Owner 阿尔法欧米伽医疗科技公司
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