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A kind of muscle and bone dredging collateral patch and preparation method thereof

A technology for dredging collaterals and joints, which is applied in medical formulas, bone diseases, and medical preparations of non-active ingredients, etc., and can solve problems such as the inactivation of active ingredients in traditional Chinese medicine extracts, increased costs, and reduced efficacy of traditional Chinese medicine patches. Achieve good therapeutic efficacy and reduce treatment cost

Active Publication Date: 2020-11-13
北京光仁堂生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The increase of the mixing temperature will lead to the inactivation of the active ingredients in the traditional Chinese medicine extract and reduce the efficacy of the traditional Chinese medicine patch. At the same time, if in order to achieve better therapeutic effect, the thickness of the layer containing the medicine paste will also need to be increased, resulting in cost increase

Method used

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  • A kind of muscle and bone dredging collateral patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Matrix preparation: take 22.5kg of glycerin, 45kg of gelatin, and 22.5kg of sodium alginate, stir evenly for 14 minutes to obtain the matrix; preparation of traditional Chinese medicine extract: take 7.5kg of Radix Aconiti, 6kg of Clematis, 6kg of Duhuo, 4.5kg of Notopterygium, Safflower 4.5kg, Chuanqiong 4.5kg, Frankincense 3kg, Myrrha 3kg, Panax notoginseng 3kg, Speranthema 1.5kg, Achyranthes bidentata 0.75kg, remove impurities, dry, pulverize, and pass through a 210-mesh sieve to obtain Chinese medicine powder; Put the obtained traditional Chinese medicine powder into water at 85°C, boil for 5 hours, concentrate the boiling liquid to 1.2 times the water density, then add 0.75 kg of borneol to the boiling liquid, and stir evenly for 35 minutes to obtain a Chinese medicine extract;

[0032] Preparation of medicated ointment: Take 12kg of 2-amino-β-1,4-glucan and 6kg of diethylaminoethyl cross-linked dextran and add it to 70L of acetic acid solution. The concentration of...

Embodiment 2

[0035] Substrate preparation: Take 20kg of glycerin, 40kg of gelatin, and 20kg of sodium alginate, stir evenly, and stir for 18 minutes to obtain the matrix; preparation of traditional Chinese medicine extract: take 5kg of Aconitum aconitum, 4kg of Clematis, 4kg of Duhuo, 6kg of notopterygium, 6kg of safflower, Chuanqiong 3kg, frankincense 3kg, myrrh 4kg, Panax notoginseng 2kg, Sperantosperm 1kg, Achyranthes bidentata 0.5kg, remove impurities, dry, pulverize, and pass through a 220-mesh sieve to obtain Chinese medicine powder; put the obtained Chinese medicine powder into Stew in water at 80°C for 5 hours, concentrate the boiled liquid to 1.3 times the water density, then add 0.5 kg of borneol to the boiled liquid, and stir evenly for 30 minutes to obtain a traditional Chinese medicine extract;

[0036] Preparation of medicated ointment: Take 10kg of 2-amino-β-1,4-glucan and 5kg of diethylaminoethyl cross-linked dextran, add it to 60L of acetic acid solution, the concentration ...

Embodiment 3

[0039]Matrix preparation: take 25kg of glycerin, 40kg of gelatin, and 20kg of sodium alginate, stir evenly, and stir for 18 minutes to obtain the matrix; preparation of traditional Chinese medicine extract: take 10kg of Radix Aconitum, 4kg of Clematis, 4kg of Duhuo, 6kg of Notopterygium, 3kg of Safflower, Chuanqiong 6kg, frankincense 4kg, myrrh 4kg, Panax notoginseng 2kg, Speranthum 2kg, Achyranthes bidentata 0.5kg, remove impurities, dry, pulverize, and pass through a 200-mesh sieve to obtain Chinese medicine powder; put the obtained Chinese medicine powder into Boil in water at 90°C for 6 hours, concentrate the boiling liquid to 1.3 times the water density, then add 0.5 kg of borneol to the boiling liquid, and stir evenly for 30 minutes to obtain a traditional Chinese medicine extract;

[0040] Preparation of medicated ointment: Take 14kg of 2-amino-β-1,4-glucan and 5kg of diethylaminoethyl cross-linked dextran, add it to 60L of acetic acid solution, the concentration of acet...

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Abstract

The invention relates to a muscle and bone meridian-dredging plaster and a preparation method thereof. The muscle and bone meridian-dredging plaster comprises a back lining layer, a medicine-containing unguent layer and a protective layer, wherein the medicine-containing unguent layer is prepared from the following raw materials in parts by weight: 80-100 parts of matrix, 30-60 parts of Chinese traditional medicine extract and 15-21 parts of additives; the Chinese traditional medicine extract is prepared from the following raw materials by weight percent: radix aconiti preparata, radix clematidis, radix angelicae pubescentis, rhizoma seu radix notopterygii, safflower, rhizoma chuanxiong, frankincense, myrrh, radix notoginseng, herba speranskiae tuberculatae, radix achyranthis bidentatae and borneol. The muscle and bone meridian-dredging plaster mainly comprises the back lining layer, the medicine-containing unguent layer and the protective layer, and the additives capable of promotingthe matrix to be combined with the Chinese traditional medicine extract are added in a preparation process of the medicine-containing unguent layer; the prepared muscle and bone meridian-dredging plaster has good effects of dispelling wind and eliminating dampness as well as promoting blood circulation to remove meridian obstruction. Furthermore, the muscle and bone meridian-dredging plaster stillhas the pharmaceutical effects after being repeatedly used for seven times, so that the treatment cost of a patient is greatly lowered.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine plasters, in particular to a muscle-bone dredging collateral plaster and a preparation method thereof. Background technique [0002] Arthralgia, limb numbness, etc. are common syndromes in limbs and bone joints, which are mostly caused by various reasons such as rheumatism and cold, hyperosteogeny, and bone and joint degenerative diseases. Although there are many different causes, the symptoms are generally similar. Once the disease occurs, it is extremely painful and seriously affects the patient's quality of life. Therefore research can alleviate at any time limbs and bone and joint position pain and the emergency health-care article of discomfort and become the important subject that solves people's health urgently needed. [0003] Currently commonly used health care products for relieving pain in limbs and joints are mainly divided into traditional Chinese medicine decoctions, wes...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/716A61K9/70A61K47/36A61P19/02A61P19/08A61P29/00A61K31/045
CPCA61K9/7023A61K31/045A61K36/185A61K36/21A61K36/232A61K36/236A61K36/237A61K36/258A61K36/286A61K36/324A61K36/328A61K36/47A61K36/714A61K36/716A61K47/36A61K2236/331A61K2236/51A61K2300/00
Inventor 徐丹丹
Owner 北京光仁堂生物科技有限公司
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