A skin-emollient medical ultrasonic coupling agent and its preparation method and use method

A technology of ultrasonic coupling agent and mixture, which is applied in echo/ultrasonic imaging agents, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve problems such as affecting inspection results, aggravating injuries, and easy loss of water

Active Publication Date: 2021-05-07
AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, many existing medical ultrasound coupling agents contain ethanol and other irritating ingredients in their formulations, and the coupling agents are directly applied to the skin, which can easily lead to telangiectasia and water loss, and patients often have dry skin and itching after examination. , and even discomfort such as allergic reactions, especially after encountering a wound, the tissue fluid in the wound will flow out due to the stimulation of the medical ultrasonic coupling agent, which will affect the examination results, cause wound pain, and even aggravate the injury

Method used

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  • A skin-emollient medical ultrasonic coupling agent and its preparation method and use method
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  • A skin-emollient medical ultrasonic coupling agent and its preparation method and use method

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preparation Embodiment 1

[0040] Chinese medicine extract of the present invention comprises the raw material of following parts by weight:

[0041] 60 parts of bitter bamboo leaves, 40 parts of aloe vera, 50 parts of plantain root, 45 parts of bougainvillea, 30 parts of bletilla striata, 20 parts of Agrimony, 40 parts of Sophora japonica, 40 parts of mugwort, 20 parts of mint, and 30 parts of Polygonum. Its preparation method is as follows:

[0042] Bitter bamboo leaves, aloe vera, plantain root, bok choy, bletilla striata, Agrimony, pagoda japonica, mugwort, mint, and Polygonum were pre-frozen at -20°C for 8 hours, and then cooled at a pressure of 0.1MPa and a temperature of -60°C. Freeze-dry at 10°C for 12 hours, then thaw and dry at 10°C for 4 hours, mix and pulverize through an 80-mesh sieve to obtain Chinese medicine powder; pack the obtained Chinese medicine powder into small bags of 10g each with filter paper, and then put them into Soxhlet In the extractor, use 75% ethanol at a solid-to-liqui...

preparation Embodiment 2

[0048] Chinese medicine extract of the present invention comprises the raw material of following parts by weight:

[0049] 90 parts of bitter bamboo leaves, 75 parts of aloe vera, 80 parts of plantain root, 80 parts of bougainvillea, 60 parts of bletilla striata, 50 parts of Agrimony, 90 parts of Sophora japonica, 80 parts of mugwort, 50 parts of mint, and 60 parts of Polygonum. Its preparation method is as follows:

[0050] Bitter bamboo leaves, aloe vera, plantain root, bok choy, bletilla striata, Agrimony, pagoda japonica, mugwort, mint, and Polygonum were pre-frozen at -20°C for 8 hours, and then cooled at a pressure of 0.1MPa and a temperature of -60°C. Freeze-dry at 10°C for 12 hours, then thaw and dry at 10°C for 4 hours, mix and pulverize through an 80-mesh sieve to obtain Chinese medicine powder; pack the obtained Chinese medicine powder into small bags of 20g each with filter paper, and then put them into Soxhlet In the extractor, use ethanol with a concentration of...

preparation Embodiment 3

[0055] Chinese medicine extract of the present invention comprises the raw material of following parts by weight:

[0056] 70 parts of bitter bamboo leaves, 55 parts of aloe vera, 65 parts of plantain root, 60 parts of bougainvillea, 50 parts of bletilla striata, 30 parts of Agrimony, 60 parts of Sophora japonica, 50 parts of mugwort, 40 parts of mint, and 50 parts of Polygonum. Its preparation method is as follows:

[0057] Bitter bamboo leaves, aloe vera, plantain root, bok choy, bletilla striata, Agrimony, pagoda japonica, mugwort, mint, and Polygonum were pre-frozen at -20°C for 8 hours, and then cooled at a pressure of 0.1MPa and a temperature of -60°C. Freeze-dry at 10°C for 12 hours, then thaw and dry at 10°C for 4 hours, mix and pulverize through an 80-mesh sieve to obtain Chinese medicine powder; pack the obtained Chinese medicine powder into small bags of 15g each with filter paper, and then put them into Soxhlet In the extractor, use ethanol with a concentration of...

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Abstract

The invention discloses a skin-emollient medical ultrasonic coupling agent, a preparation method and a using method thereof, and relates to the technical field of medical ultrasonic coupling agent, comprising 8-12 parts of glyceryl monostearate, 6-10 parts of stearic acid, ten 0.5-1.5 parts of hexaalkyl alcohol, 0.08-0.12 parts of paraben, 0.5-1.5 parts of olive oil, 60-80 parts of distilled water, 10-15 parts of sodium stearyl polyoxyethylene ether phosphate, 0.5 parts of chitosan ‑1.2 parts, 8‑15 parts of glycerol, 0.5‑1.5 parts of triethanolamine, 3‑8 parts of traditional Chinese medicine extract, 40‑60 parts of distilled water. The ultrasonic coupling agent prepared by the invention has the advantages of rapid disinfection and sterilization, less air bubbles and clear imaging, superior biocompatibility, high lubricating performance, moisturizing and moisturizing, etc., can reduce the friction between the probe surface and the skin, and make the probe It can be flexibly slid and explored; and the medical ultrasonic coupling agent for skin has little irritation, has good anti-inflammatory and hemostatic effects, and will not flow out of tissue fluid due to stimulation after encountering a wound. Ultrasound diagnosis is convenient and has a strong effect of promoting wound healing.

Description

technical field [0001] The invention relates to the technical field of medical ultrasonic coupling agent, in particular to a skin-emollient medical ultrasonic coupling agent and its preparation method and use method. Background technique [0002] When ultrasonic waves are incident on the interface between two different media, the greater the difference in impedance between the two media, the greater the reflection coefficient, and the less sound energy that passes through the interface into another medium. For medical ultrasound, if the probe is in "dry contact" with the skin, the ultrasonic waves emitted by the probe cannot enter the human body at all due to the strong reflection of the air layer between the two. For this reason, a certain substance must be filled between the surface of the probe and the skin to drive out the air and form a channel for the smooth and undistorted transmission of ultrasonic waves. This substance is called a medical ultrasonic coupling agent. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/22A61K36/899A61P31/02A61P17/02A61P7/04A61P29/00
CPCA61K36/282A61K36/489A61K36/534A61K36/704A61K36/73A61K36/78A61K36/88A61K36/886A61K36/896A61K36/898A61K36/899A61K49/222A61K2300/00
Inventor 张东竹
Owner AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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