Implantable biological brain electrode multi-stage propulsion system and operation method thereof

Abstract

The invention discloses an implantable biological brain electrode multi-stage propulsion system and an operation method thereof. A bioelectrode is three-stage advancement, and comprises a positioningstage, an advancement stage and a conductive stage in turn. The positioning stage is used to fix the position of the electrode body and break through endocraniums and arachnoids. The tip reaches the outside of the arachnoids, so as to prevent inflammatory reaction caused by damaged tissues brought into the cerebral cortex by the electrode. The advancement stage is used to carry the conductive stage to a target implantation site in the cortex. The conductive stage is made of a core wire and a conductive biomaterial. A communicated porous structure is inside the conductive biomaterial. Nerve inducing factors are perfused onto the porous conductive biomaterial to realize inducing nerve cell synapse ingrowth and electroneurographic signal acquisition. Based on a biological neural interface made of a natural material, natural coupling and functional transition from a biologically active neural network organization to an information sensing device can be realized through the induction of nerve cell synapses, and technical and model foundations are provided for the perfect transition of a brain instruction terminal and an external information acquisition terminal.

Description

technical field [0001] The invention belongs to the technical field of biological electrodes, and in particular relates to an implantable biological brain electrode multistage propulsion system and an operation method thereof. Background technique [0002] Brain science is one of the important development directions of scientific research today, and it is one of the commanding heights of scientific competition among countries in the world. The most applied and challenging aspect of all brain science research is the development of implantable neural interfaces. Implantable neural interfaces have shown great application prospects in the medical field, including cochlear implants and deep brain stimulation to treat neurological diseases. Considerable progress has been made. [0003] At present, implanted devices are mainly made of materials such as silicone rubber or metal. Although they have shown advantages in signal transmission and processing, they cannot achieve long-term...

AI Technical Summary

Problems solved by technology

This layer of coated tissue prevents the direct contact between the electrodes and the surrounding nerve tissue, which is important for the electrodes to record EEG signals, because the signals from neurons are very weak, after weeks to months. , the coating may cause poor contact between the electrode and the neural tissue, increasing system noise and thus degrading the quality of the detected neural signal

Therefore, problems such as tissue infection, poor signal quality, and signal loss caused by the mismatch between traditional material properties and neural tissue, poor material biocompatibility, and unreasonable implantation methods make it impossible for neural interface devices to be implanted in the brain for a long time and achieve stability. neural signal

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