76results about How to "Avoid rejection" patented technology

A corneal epithelial sheet having a cell layer similar to the anterior epithelium of cornea. A corneal epithelial sheet is obtained through the step (a) of separately preparing a first cell being a self cell and a second cell whose origin is different from that of the first cell, the step (b) of planting the first cell and the second cell on a collagen layer and culturing them, and the step (c) of after proliferation of the first cell and second cell resulting in formation of a cell layer, bringing the outermost stratum of the cell layer into contact with air.

The invention relates to a method for infusing by various drugs at various speeds and a device thereof. The device at least comprises a pump body and an infusion vessel which is connected with the pump body, wherein, the infusion vessel is provided with a drug input terminal and a drug output terminal. The device is characterized in that the pump body is provided with a plurality of cavities, and the top of the pump body is provided with a drug puncture film; the infusion vessel is provided with a plurality of vessel cavities; at least one vessel cavity is communicated with one cavity; other vessel cavities are respectively communicated with the corresponding cavities; the outer side of the infusion vessel is provided with a plurality of drug storing sacks with high elasticity which are communicated with corresponding cavities through a plurality of drug input holes on the vessel cavities and are communicated with the drug output terminal of the vessel cavities through a plurality of drug output holes on the corresponding vessel cavities. The infusion device can realize the combination of infusing large doses of drug once and continuous infusing drug with low concentration, thus remaining required drug concentration required by treatment, being beneficial to improving treatment effect and improving the life quality of patients effectively owning to convenient operation. The invention has the advantages of easy processing and manufacture as well as low cost.

The invention provides a method for constructing tissue engineering skin. In the method, human epidermal stem cells and hypodermal fibroblasts are taken as seed cells, and a homologous acellular dermal matrix modified by a human placental type IV collagen is taken as a stent, so that active dual-layer engineering skin is compounded and constructed by using a gas-liquid interface separate culture method. The tissue engineering skin constructed by using the method is closer to the structure of natural skin; and as proved by histomorphology, the tissue engineering skin has an epidermal and hypodermal double-layer structure, wherein the hypodermal collagen stent has a complete structure, an epidermal layer is provided with a plurality of layers of cells of different differentiation degrees, and the morphological requirement of the tissue engineering skin is met.

The invention relates to medical consumables for drainage of human wounds, which is a three-chamber negative pressure wound irrigation and drainage tube. It includes an internal drainage tube and an external connection tube; the internal drainage tube is an integral structure, and the internal drainage tube is provided with a main drainage tube, a flushing tube, and a guide wire implantation tube in parallel in the longitudinal direction; the main drainage tube is located in the The geometric center of the drainage tube inserted in the body, the irrigation tube and the guide wire implant are located on the periphery of the main drainage tube; the outer wall of the drainage tube inserted in the body is provided with a lower groove, and there are multiple drainage openings in the lower groove. It is connected with the main drainage tube; the extracorporeal connecting tube includes the independent extracorporeal drainage tube, extracorporeal irrigation tube and extracorporeal guide wire implantation tube; The main drainage tube, irrigation tube and guide wire implant tube at the outer end are in continuous communication. Its main structure is a three-chamber structure, which is used for drainage of deep wounds in the human body, and has the effects of accurate placement, good drainage, flushing, and anti-blockage.