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Throat lozenge and preparation method thereof

A throat-moistening tablet and throat-moistening technology, which is applied in pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve the problems of poor effect, insufficient anti-inflammatory and detoxification functions, etc. Injury, enhance, enhance, enhance the effect of the body

Inactive Publication Date: 2018-06-05
杨忠华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Technical problem to be solved by the present invention: Aiming at the problem that throat moistening tablets in the current market are mainly used for throat moistening and relieving cough, the anti-inflammatory and detoxifying functions are not strong enough, and the effect is poor, a throat moisturizing tablet and its preparation method are provided

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Throat-moistening active extract A: take ghost needle grass and add 70% methanol solution at a mass ratio of 1:8, extract at 25°C for 5 days, filter with suction, take the filtrate and concentrate under reduced pressure to obtain a concentrate, take the paste and press Mix with water at a mass ratio of 1:10, extract with petroleum ether, ethyl acetate, and n-butanol for 3 times in sequence, combine the extracts, and rotate to evaporate to obtain throat-moistening active extract A.

[0027] Throat-moistening active extract B is taken from the stem bark of Gewang, crushed through an 80-mesh sieve, collected the sieved particles, added ethanol with a mass fraction of 95% at a mass ratio of 1:10, ultrasonically extracted at 140W for 1 hour, filtered, and the filtrate was taken. Rotary evaporation, get throat-moistening active extract B.

[0028] Throat protectant is to take Pseudostellariae Radix Pseudostellariae powder and mix it with distilled water at a mass ratio of 1:9...

Embodiment 2

[0033] Throat-moistening active extract A: take ghost needle grass and add 70% methanol solution at a mass ratio of 1:8, extract at 30°C for 5 days, filter with suction, take the filtrate and concentrate under reduced pressure to obtain a concentrate, take the paste and press Mix with water at a mass ratio of 1:10, extract with petroleum ether, ethyl acetate, and n-butanol for 3 times in sequence, combine the extracts, and rotate to evaporate to obtain throat-moistening active extract A.

[0034] Throat-moistening active extract B is taken from the stem bark of Gewang, crushed through an 80-mesh sieve, collected the sieved particles, added ethanol with a mass fraction of 95% at a mass ratio of 1:10, ultrasonically extracted at 150W for 1.2h, filtered, and the filtrate was taken , Rotary evaporation, get throat active extract B.

[0035] Throat protectant is to take Pseudostellariae Radix Pseudostellariae powder and mix it with distilled water at a mass ratio of 1:9, extract at...

Embodiment 3

[0040] Throat-moistening active extract A: Take ghost needle grass and add 70% methanol solution at a mass ratio of 1:8, extract at 32°C for 6 days, filter with suction, take the filtrate and concentrate under reduced pressure to obtain a concentrate, take the paste and press Mix with water at a mass ratio of 1:10, extract with petroleum ether, ethyl acetate, and n-butanol for 3 times in sequence, combine the extracts, and rotate to evaporate to obtain throat-moistening active extract A.

[0041] Throat-moistening active extract B is taken from the stem bark of Gewang, crushed through an 80-mesh sieve, collected the sieved particles, added ethanol with a mass fraction of 95% at a mass ratio of 1:10, ultrasonically extracted at 160W for 1.5h, filtered, and the filtrate was taken , Rotary evaporation, get throat active extract B.

[0042] Throat protectant is to take Pseudostellariae Radix Pseudostellariae powder and add distilled water in a mass ratio of 1:9 to mix, extract at ...

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Abstract

The invention relates to the technical field of traditional Chinese medicine and in particular relates to a throat lozenge and a preparation method thereof. Active ingredients in barks of sticktight and Indian stringbush root are extracted, the sticktight has effects of dispelling wind, clearing heat and relieving exterior syndrome, can relieve symptoms such as sore throat, cough and abundant sputum and is capable of clearing heat and relieving sore-throat; active ingredients of the Indian stringbush root mainly include flavonoids, coumarins, polysaccharides and the like; daphnoretin, a component of the coumarins, is a main effective component of the plant, mainly exists in the bark of the Indian stringbush root, has effects of diminishing inflammation, reducing phlegm and resolving masse,relieving swelling and pain and the like and contributes to relieving the pharyngitis symptom. A stress source of the throat is formed aiming at pharyngitis and cough, and if an organism is in a long-term stress state, the throat swells and is torn to be damaged. Polysaccharide components of radix pseudostellariae have effects of enhancing the body, resisting stress, realizing immunological enhancement and the like; on one hand, damage of the throat due to long-term inflammatory stimulation and cough can be reduced; on the other hand, immune resistance of the throat is enhanced.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a throat lozenge tablet and a preparation method thereof. Background technique [0002] The survey shows that the number of patients with acute and chronic pharyngitis is increasing day by day, and the disease has seriously affected their work and life, especially in the profession of teachers. Due to the particularity of their work, chronic pharyngitis has become their exclusive "occupational disease". Therefore, There are also some medicines and health care products for treating pharyngitis frequently appearing on the market. Throat lozenges are the most widely used category among them. However, no matter whether it is Western medicine or traditional Chinese medicine, if it is not taken according to the symptoms or taken in excess, it will cause certain damage to the body. , especially throat lozenges containing traditional Chinese medicine ingredients, be...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/83A61K9/20A61K47/36A61K47/38A61P11/04A61P11/14
CPCA61K9/205A61K9/2054A61K36/185A61K36/28A61K36/36A61K36/83A61K2236/331A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2300/00
Inventor 杨忠华郑薇林凡
Owner 杨忠华
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