10 results about "Throat irritation" patented technology

Tree pollen allergy is seasonal allergy caused by various tree pollen spread in air. The allergy affects a substantial proportion of populations, is particularly significant in European and North America areas, and is characterized by symptoms such as sneezing, nasal obstruction, rhinorrhea, eye itching and lacrimation, and throat irritation. The symptoms typically occur in spring, at which birch, alder, hazel and oak release pollen into the air. Tree pollen allergy is a type 1 hypersensitivity reaction mediated by an immunoglobulin E (IgE) antibody. The present invention relates to antibodies and antigen binding fragments thereof that bind to one or more of tree pollen allergens Bet v 1, Aln g 1, Cor a 1 and Quue a 1, resulting in inhibition of IgE-mediated anaphylaxis.

The invention provides a device for treating at least one of rhinitis, congestion, and / or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, coughing, sneezing, nasal or throat irritation and itching, and difficulty sleeping. The device includes a shaft, a retractable and expandable end effector, and handle, that, as a whole, provide a high level of precise control and feedback to an operator during a procedure. The shaft includes an electrode array provided along a length thereof configured to deliver energy to specific target sites within the nasal passage and nasal cavity in conjunction with neuromodulation provided by the end effector.

Systems and methods are provided for delivering neurostimulation therapies to patients. Stimulation from an implantable medical device (IMD) may be suspended in response to detecting a patient discomfort event, such as a cough, throat irritation, or voice alteration. The suspension period may be based on at least one of a severity level of the patient discomfort event and a patient physical state, such as being asleep or lying down. Detection of a patient discomfort event may be calibrated.

Systems and methods are provided for delivering neurostimulation therapies to patients. Stimulation from an implantable medical device (IMD) may be suspended in response to detecting a patient discomfort event, such as a cough, throat irritation, or voice alteration. The suspension period may be based on at least one of a severity level of the patient discomfort event and a patient physical state, such as being asleep or lying down. Detection of a patient discomfort event may be calibrated.

The invention provides bacillus velezensis and an application thereof. The bacillus velezensis disclosed by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.30646. According to the seed melon spice for the tobacco prepared through fermentation of the strain, the characteristic component L-citrulline can be efficiently enriched, and the content of several key flavor substances including aldehydes (such as (E)-4-nonenal, (E)-2-nonenal and nonanal) and alcohols (such as Z-3-nonene-1-ol and 1-nonanol) is increased. Cigarette flavoring sensory evaluation shows that the spice can coordinate and fuse the original fragrance of tobacco, endows the cigarette with fresh and sweet note characteristics, effectively supplements the faint scent, the fruit fragrance and the sweet fragrance, remarkably improves the richness of the smoke fragrance, improves the texture of the cigarette smoke, softens and delicate the smoke, reduces the irritation and dryness of the throat, and integrally improves the smoking experience.

This application provides an atomizing liquid and its preparation method, wherein the atomizing liquid comprises the following components in parts by weight: 50-68 parts distilled water; 10-20 parts propylene glycol; 7-8 parts nicotine salt; 20-28 parts water-soluble flavoring; 0.5-2 parts humectant; 0.15-0.5 parts cooling agent; 0.8-1.5 parts sweetener; and 0.05-0.15 parts pH adjuster. The atomizing liquid and its preparation method provided in this application, comprising specific parts by weight of distilled water, propylene glycol, nicotine salt, and other components, effectively alleviate the burning and dryness in the throat caused by high nicotine concentrations by optimizing the formula ratio and preparation process. It has the advantages of reducing throat irritation and improving user comfort at high nicotine concentrations.

A botanical matrix and base for vaporizer production are described. The base includes propanediol, vegetable glycerin, and a blend of two or more botanical additives. The propanediol and glycerin can be produced in a laboratory for greater consistency. Additional ingredients, including active ingredients, can be added to the base to manufacture the vaporizer. The botanical additives provide a smoother feel to the base and reduce or eliminate throat irritation.

The invention belongs to the technical field of production of tobacco flavors and fragrances, and particularly relates to a preparation method of an alcohol-soluble tremella fuciformis extract and application of the alcohol-soluble tremella fuciformis extract in cigarettes. According to the method, the alcohol-soluble tremella fuciformis extract is obtained by combining a two-step enzymolysis process with a membrane technology. The tremella fuciformis extract obtained through the extraction method is diluted with ethyl alcohol and then evenly sprayed into tobacco shreds to be used as natural tobacco flavor, and a prepared cigarette has the style characteristics of being coordinated with natural tobacco flavor, improving smoke definition and improving sweet feeling, throat irritation and aftertaste can be obviously improved, oral cavity moist feeling and comfortable feeling can be improved, and the taste of the cigarette is improved. And the cigarette quality is improved. The preparation method of the tremella extract provided by the invention solves the problem of precipitation of the tremella aqueous extract in an ethanol solvent, is convenient for large-scale and industrial production, and has relatively high economic benefits.

The invention relates to the field of tobacco, in particular to a nicotine product and a preparation method thereof. The nicotine product is prepared from the following components in parts by mass: 0.1 to 0.3 part of taste improving composition, 50 to 90 parts of glycosyl, 0.1 to 1 part of nicotine salt, 0.1 to 10 parts of essence and perfume and 0.1 to 5 parts of auxiliary materials. By adding the taste improving composition, the nicotine product is mild and smooth in mouth, burning feeling and strong throat irritation caused by free alkali nicotine are greatly reduced, user experience is better and easier to accept, and flavor and taste are fuller. Meanwhile, the toothpaste is more convenient to use, does not need to be placed at positions such as gingival roots, is convenient to store, and is free of residues and pollution after being eaten.

The invention provides a preparation method of a dried orange peel Maillard reactant as well as a product and application thereof, and the method comprises the following steps: (1) preparation of a dried orange peel crude extract: digesting dried orange peel powder in an ethanol water solution to obtain the dried orange peel crude extract; and (2) preparing the dried orange peel Maillard reactant: mixing the dried orange peel crude extract with monosaccharide and amino acid to react, and concentrating to obtain the dried orange peel Maillard reactant. According to the method, the pericarpium citri reticulatae is extracted, then the pericarpium citri reticulatae extract, monosaccharide and amino acid are subjected to the Maillard reaction to obtain the pericarpium citri reticulatae Maillard reactant, and after the pericarpium citri reticulatae Maillard reactant is added into the heated cigarette, the smoke concentration of the heated cigarette can be increased, the smoke quality can be improved, throat irritation can be reduced, and smoke inductivity and oral aftertaste can be improved; the oral sweet feeling is increased, and a relatively good application effect is achieved.