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Medicine for treating heart failure in pet dogs

A technology for heart failure and pet dogs, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of relatively large drug use restrictions, and achieve the effect of good compatibility between raw materials, strong practicability, and high purity

Inactive Publication Date: 2018-06-08
KUNMING MEDICAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing drug treatments are often accompanied by strong side effects, such as high blood pressure, abnormal renal function, etc., which greatly restrict the use of drugs. Therefore, the optimal development of heart failure drugs is still imminent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A medicine for treating heart failure in pet dogs, including a main drug and auxiliary materials, the main drug includes the following percentage components: 0.5% cannabinoid, 1% hemp oil, 1% chitin, and the balance of cannabidiol, Among them, cannabinoids, hemp oil, and cannabidiol are extracted from industrial hemp, and chitin is extracted from fish scales or oyster shells.

[0024] The main drug preparation steps are as follows:

[0025] 1) Wash and dry the industrial hemp leaves and industrial hemp seeds, crush the industrial hemp leaves and pass through a 60-80 mesh sieve, grind the industrial hemp seeds through a 100-120 mesh sieve, and place the industrial hemp leaves in 80% (v / v) ethanol solution medium, soak at 40±2°C for 4 hours, filter, and keep the filtrate and filter residue for future use; industrial hemp seeds are made by low-temperature cold pressing method to make oil, and keep the oil residue for future use;

[0026] 2) blending the filtrate with the ...

Embodiment 2

[0033] A medicine for treating heart failure in pet dogs, including main ingredients and auxiliary materials, the main ingredients include the following percentage components: 1.8% cannabinoids, 1.5% hemp oil, 0.8% chitin, and the balance of cannabidiol, Among them, cannabinoids, hemp oil, and cannabidiol are extracted from industrial hemp, and chitin is extracted from fish scales or oyster shells.

[0034] The main drug preparation steps are as follows:

[0035] 1) Wash and dry the industrial hemp leaves and industrial hemp seeds, crush the industrial hemp leaves and pass through a 60-80 mesh sieve, grind the industrial hemp seeds through a 100-120 mesh sieve, and place the industrial hemp leaves in 80% (v / v) ethanol solution medium, soak at 40±2°C for 5 hours, filter, and keep the filtrate and filter residue for later use; industrial hemp seeds are made by low-temperature cold pressing method to make oil, and keep the oil residue for later use;

[0036] 2) blending the filt...

Embodiment 3

[0043] A medicine for treating heart failure in pet dogs, including main ingredients and auxiliary materials. The main ingredients include the following percentage components: 2.6% cannabinoids, 1% hemp oil, 0.5% chitin, and the balance of cannabidiol, Among them, cannabinoids, hemp oil, and cannabidiol are extracted from industrial hemp, and chitin is extracted from fish scales or oyster shells.

[0044] The main drug preparation steps are as follows:

[0045] 1) Wash and dry the industrial hemp leaves and industrial hemp seeds, crush the industrial hemp leaves and pass through a 60-80 mesh sieve, grind the industrial hemp seeds through a 100-120 mesh sieve, and place the industrial hemp leaves in 80% (v / v) ethanol solution medium, soak at 40±2°C for 2 hours, filter, and keep the filtrate and filter residue for later use; industrial hemp seeds are made by low-temperature cold pressing method to make oil, and keep the oil residue for later use;

[0046] 2) blending the filtra...

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PUM

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Abstract

The invention provides a medicine for treating heart failure in pet dogs. The medicine for treating the heart failure in the pet dogs is prepared from main medicines and auxiliary materials, the mainmedicines are prepared from the following percentage components: 0.5 to 5% of cannabinoid, 0.5 to 5% of cannabis oil, 0 to 1.2% of chitin, the balance of cannabidiol, wherein the cannabinoid, the cannabis oil, and the cannabidiol are extracted from industrial hemp, and the chitin is extracted from fish scales or oyster shells, and the auxiliary materials are medically acceptable auxiliary materials used for each dosage. The medicine prepared by the invention has good compatibility between the prepared pharmaceutical raw materials, and by conducting tests of preventing and treating heart failure in mice, the medicine has good therapeutic effects, and has small toxic and side effects, can be prepared into different dosage forms of drugs by conventional techniques, and has strong practicality.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating heart failure in pet dogs. Background technique [0002] The myocardium is seriously injured, so that the heart cannot pump enough blood normally to supply the activities and metabolism needs of various organs of the body. As a result, the heart gradually becomes hypertrophic and loses heart function. This is called heart failure. Diseases that may cause heart failure include: congenital heart disease and acquired heart disease, heart valve disease, myocarditis, pericarditis, etc. In addition, some diseases other than the heart can also cause heart failure, such as acute nephritis, stubborn hypertension , Chronic lung disease. [0003] The mammalian heart is divided into two completely separated chambers, the left and right. It is a practical method to distinguish early heart failure according to the difference in function between the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P9/04A61K31/557A61K31/726A61K31/05
CPCA61K31/05A61K31/557A61K31/726A61K36/60A61K2236/333A61K2236/37A61K2300/00
Inventor 张瑞林吕嘉王尚文张冬先曾晓锋洪仕君李树华王蕊解润芳刘悦鑫
Owner KUNMING MEDICAL UNIVERSITY
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