Traditional Chinese medicine compound composition capable of treating hypertensive patients with diabetes as well as preparation method and application thereof

A technology for hypertension and diabetes, which is applied in the field of traditional Chinese medicine compound composition and its preparation, can solve the problems of lack of clinical drug efficacy research and inconsistent treatment principles, and achieve safe and reliable medication, less toxic and side effects, and scientific and reasonable ratio of Chinese medicine compound formula Effect

Active Publication Date: 2018-06-15
严士海
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many drugs for the treatment of hypertension combined with diabetes. Although the western medicines used clinically have certain curative effects, most of them have relatively large adverse reactions, such as rebound after drug withdrawal, liver and kidney damage, rhabdomyolysis and other side effects. TCM has unique advantages in the treatment of hypertension combined with diabetes. There are many prescriptions and medicines for the prevention and treatment of hypertension combined with diabetes, and the curative effect is relatively long-lasting, and most of them have no obvious side effects. Prefer unilateral and proven prescriptions, lack of systematic and comprehensive clinical efficacy research, and the basis of traditional Chinese medicine prescriptions is different, and the treatment principles are not uniform

Method used

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  • Traditional Chinese medicine compound composition capable of treating hypertensive patients with diabetes as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1. A traditional Chinese medicine compound composition with the effects of treating hypertension combined with diabetes, which is made of the following raw materials in parts by weight: Codonopsis 15g, Rehmannia glutinosa 15g, Salvia miltiorrhiza 10g, Huai Mi 10g, 10 parts of bamboo leaves, and reed rhizome 10g , kudzu root 10g, perilla seed 10g.

[0028] 2. The preparation method of the Chinese medicine compound composition having the effect of treating hypertension combined with diabetes according to the present invention, which comprises the following steps:

[0029] (1) Take 15g of Codonopsis pilosula, 15g of raw land, 10g of salvia miltiorrhiza, 10g of Chinese pagoda root, 10g of reed root, and 10g of pueraria lobata in parts by weight, add 10 times the weight of medicinal materials and decoct for extraction 3 times, each time for 1 hour, and combine the extracts , concentrate to obtain the extract, and set aside;

[0030] (2) Take 10 g of bamboo leaves and 10 g o...

Embodiment 2

[0033] 1, a kind of Chinese medicine compound composition that has the effect of treating hypertension combined with diabetes, it is made of the crude drug of following parts by weight: Codonopsis 45g, Radix Rehmanniae 45g, Salvia miltiorrhiza 30g, Sophorae japonica 30g, Bamboo leaves 30g, Reed rhizome 30g, Pueraria root 30g, perilla seed 30g.

[0034] 2. The preparation method of the Chinese medicine compound composition having the effect of treating hypertension combined with diabetes according to the present invention, which comprises the following steps:

[0035] (1) Get 45g of Codonopsis pilosula in parts by weight, 45g of raw land, 30g of salvia miltiorrhiza, 30g of Huai Mi, 30g of reed rhizome, 30g of pueraria lobata, add 8 times of the weight of medicinal materials to reflux and extract 2 times, each time for 2 hours, combine the extracts, Concentrated extract, set aside;

[0036] (2) Take 30 g of dandelion leaves and 30 g of perilla seeds in parts by weight, reflux e...

Embodiment 3

[0039] 1, a kind of Chinese medicine compound composition that has the effect of treating hypertension combined with diabetes, it is made of the crude drug of following parts by weight: Codonopsis 30g, Radix Rehmanniae 30g, Salvia miltiorrhiza 20g, Chinese pagoda japonica 20g, 20g of bamboo leaves, 20g of reed rhizome, Pueraria root 20g, perilla seed 20g.

[0040] 2. The preparation method of the Chinese medicine compound composition having the effect of treating hypertension combined with diabetes according to the present invention, which comprises the following steps:

[0041](1) Get 30g of Codonopsis pilosula, 30g of raw land, 20g of salvia miltiorrhiza, 20g of pagoda japonica, 20g of reed root, and 20g of pueraria lobata by weight, add 12 times of the weight of the medicinal material to reflux and extract for 2 times, each time for 1 hour, and combine the extracts, Concentrated extract, set aside;

[0042] (2) Take 20 g of dandelion leaves and 20 g of perilla seeds in par...

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Abstract

The invention discloses a traditional Chinese medicine compound composition capable of treating hypertensive patients with diabetes as well as a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 15-45 parts of codonopsis pilosula, 15-45 parts of rehmannia root, 10-30 parts of danshen root, 10-30 parts of sophora flower bud, 10-30 parts of common lophatherum herb, 10-30 parts of reed rhizome, 10-30 parts of kudzuvine root, and 10-30 parts of perilla seed. The traditional Chinese medicine compound composition provided by the invention adopts a theory of treatment according to syndrome differentiation to have a prescription, and clinical experimental results show that the traditional Chinese medicine compound composition provided by the invention has comprehensive effects of multiple links and multiple targets, can improve clinical symptoms of hypertensive patients with diabetes, has the effects of lowering blood pressure and blood sugar and improving insulin resistance, and can be used for preventing and treating the hypertensive patients with diabetes; and the clinical experimental results show that the traditional Chinese medicine compound provided by the invention has no adverse reaction after long-term use and is safer to use.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition capable of treating hypertension combined with diabetes, a preparation method and application thereof. Background technique [0002] The incidence of essential hypertension (Essentia hypertension, EH) combined with type 2 diabetes mellitus (Type 2 Diabetes Mellitus, T2DM) is increasing year by year, and the incidence of hypertension combined with diabetes accounts for as high as 20% to 40% of the hypertensive population. The co-morbidity of EH and T2DM greatly increases the incidence of cardiovascular and cerebrovascular events and kidney damage, seriously infringing on the physical and mental health of patients. [0003] At present, there are many drugs for the treatment of hypertension combined with diabetes. Although the western medicines used clinically have certain curative effects, most of them have relatively lar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10A61P9/12
CPCA61K36/344A61K36/488A61K36/489A61K36/535A61K36/537A61K36/804A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 严士海严冬张舒刘福明刘顺李婕耿志荣
Owner 严士海
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