Medicinal composition and application thereof

A composition and drug technology, applied in the fields of drug combination, application, food science, etc., can solve the problems of high price, long course of disease, and many disease links, and achieve the effects of reasonable and ingenious formula, good therapeutic effect, and safe formula.

Inactive Publication Date: 2018-06-19
北京知蜂堂健康科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The etiology of AD is complex, the course of the disease is long, and there are many stages of onset. Aspartate receptor (NMDA receptor) antagonists (such as memantine), but the above-mentioned drugs are expensive, and there are many adverse drug reactions, such as hallucinations, confusion, dizziness, headache, nausea, abdominal pain, diarrhea and fatigue after taking the drug. Significant, and its drug effect can only delay the disease, but cannot ultimately control or reverse the patient's disease

Method used

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  • Medicinal composition and application thereof
  • Medicinal composition and application thereof
  • Medicinal composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] In this embodiment, the pharmaceutical composition comprises the following components in mass fractions:

[0057]

[0058]

[0059] The plant extracts include valerian extract, spearmint extract, ginkgo extract, Bacopa serrata extract, gastrodia elata extract, American ginseng extract, Hericium erinaceus extract, rosemary extract, grape seed extract , hop extract and polygala extract, edible auxiliary materials are stabilizer and flavoring agent.

Embodiment 2

[0061] In this embodiment, the pharmaceutical composition comprises the following components in mass fractions:

[0062]

[0063]

[0064] The plant extracts include valerian extract, spearmint extract, ginkgo extract, Bacopa serrata extract, gastrodia elata extract, American ginseng extract, Hericium erinaceus extract, rosemary extract, grape seed extract , hop extract and polygala extract, edible auxiliary materials are stabilizer and flavoring agent.

Embodiment 3

[0066] In this embodiment, the pharmaceutical composition comprises the following components in mass fractions:

[0067]

[0068] The plant extracts include spearmint extract, ginkgo biloba extract and Bacopa monnieri extract.

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Abstract

The invention provides a medicinal composition and an application thereof. The medicinal composition comprises, by weight, 10-92.68% of lyophilized honeybee pupae powder, 5-80% of lyophilized royal jelly powder, 0.5-10% of phosphatidylserine, 0.5-10% of gamma-aminobutyric acid, 0.5-10% of cis-15-tetracosenoic acid, 0.5-50% of plant extract, 0.2-18% of an assistant and 0.12-18% of an antioxidant, wherein the sum of the weight percentages of all above components is 100%. The medicinal composition has the advantages of reasonable and ingenious formula, fast effect, excellent treatment effect on Alzheimer's disease caused by different causes, safe and reliable formula, no toxic or side effects, and high application prospects and application values in medicine therapy.

Description

technical field [0001] The invention belongs to the field of medicinal chemistry, and relates to a medicinal composition and application thereof. Background technique [0002] Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive impairment and memory impairment, and is the most common form of Alzheimer's disease. In 1994, at the tenth meeting of the International Alzheimer's Association in Edinburgh, UK, September 21 was designated as "World Alzheimer's Disease Day". Clinically, it is characterized by generalized dementia manifestations such as memory impairment, aphasia, agnosia, impairment of visuospatial skills, executive dysfunction, and personality and behavioral changes. The characteristic pathological changes are extracellular senile plaques formed by β-amyloid deposition, intraneuronal neurofibrillary tangles formed by hyperphosphorylation of tau protein, and neuronal loss with gliosis. [0003] With the intensification of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/84A61K36/534A61K36/16A61K36/80A61K36/8988A61K36/258A61K36/07A61K36/53A61K36/87A61K36/60A61K36/69A61P25/28A23L33/00A23L33/175A23L33/12A61K35/644A61K35/64A61K31/685A61K31/201A61K31/197A61K31/405
CPCA23L33/00A23L33/12A23L33/175A23V2002/00A61K31/197A61K31/201A61K31/405A61K31/685A61K35/63A61K35/644A61K36/07A61K36/16A61K36/258A61K36/53A61K36/534A61K36/60A61K36/69A61K36/80A61K36/84A61K36/87A61K36/8988A61K2300/00A23V2200/322A23V2250/038A23V2250/065A23V2250/0646A23V2250/186
Inventor 黄冀东黄雪梅刘俊熙
Owner 北京知蜂堂健康科技股份有限公司
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