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Determination and acquisition method of normalized correction factor and medical imaging method

An acquisition method and correction factor technology, applied in the field of image processing, can solve the problems of response line compliance efficiency fluctuation, difficult to normalize correction factor, insufficient sampling data volume, etc., to eliminate the influence of coincidence, good detector characteristics, less demanding effects

Active Publication Date: 2021-02-26
RAYSOLUTION DIGITAL MEDICAL IMAGING CO LTD
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Problems solved by technology

This effect will be very obvious for low counts, when there are only a few tens or even a few samples on each LOR, we can't even tell whether these events are noise
Therefore, when using the existing normalization correction method to correct the scanned PET data, there are the following two problems: 1. The response line conforms to the efficiency fluctuation, and the consistency is poor after normalization correction according to the existing method; 2. At present, the amount of sampled data is insufficient, and it is difficult to form an accurate normalized correction factor

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  • Determination and acquisition method of normalized correction factor and medical imaging method
  • Determination and acquisition method of normalized correction factor and medical imaging method
  • Determination and acquisition method of normalized correction factor and medical imaging method

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Embodiment Construction

[0046] An embodiment of the present invention discloses a method for obtaining a normalized correction factor, comprising the following steps:

[0047] S1 performing actual data collection for a specified time on the phantom with an initial uniform activity, the volume of which covers the target imaging field of view;

[0048] Wherein, in step S1, a PET detection system is used to collect data on a cylindrical phantom with uniform activity, and the imaging field of view is a three-dimensional space (field of view, referred to as “field of view”) in the PET detection system that can be used to place the scanned object and perform imaging. FOV), that is, the prosthesis cannot be smaller than the FOV used, the activity range is 0.01mCi-50mCi, and the scanning time is 1min-200min. The cylindrical phantom is a cylindrical shell, and the inner cavity can be injected with a PET tracer solution to be used as a radiation source for imaging; the scanning time refers to the time from the...

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Abstract

The invention discloses a method for obtaining a normalized correction factor, which determines the normalized correction factor of the response line where the single channel is located based on the count rate of the single channel, including the following steps: Carry out actual data collection at a specified time, the volume of the prosthesis covers the target imaging field of view; S2 based on the actual data, obtain the actual event count SR of the i-th and j-th single channels on any one of the response lines i 、SR j ; S3 based on the same activity and scan time, theoretical data collection for the same size of the prosthesis; S4 based on the theoretical data, to obtain the theoretical event count ST of the i, j single channel on the corresponding response line i , ST j ; S5 determines the response line normalization correction factor NS ij = NS ij =(ST i *ST j ) / (SR i *SR j ), the normalized correction factor determined by this method is based on the counting rate of a single channel for statistics, which requires low data volume and can better reflect the detector characteristics of the system.

Description

technical field [0001] The invention relates to the technical field of image processing, in particular to a method for determining and acquiring a normalized correction factor and a medical imaging method. Background technique [0002] PET is the abbreviation of Positron Emission Tomography in English. The clinical imaging process is as follows: label the radionuclides (such as F-18, etc.) in the subject's body. Allow the subject to perform a PET scan within the effective field of view of the PET. The positrons emitted by the radionuclide move about 1 mm in the body and combine with the negative electrons in the tissue to produce annihilation radiation, producing two gamma photons with equal energy (511KeV) and opposite directions. The detection device of the PET system can detect the gamma photon pair, and then analyze the existence of positrons, and reconstruct the PET image reflecting the metabolism of various tissues of the organism, and obtain the concentration distr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/03A61B6/00
CPCA61B6/037A61B6/582
Inventor 李炳轩
Owner RAYSOLUTION DIGITAL MEDICAL IMAGING CO LTD
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