Toothpaste containing lactobacillus paracasei and preparation method of toothpaste

A technology of Lactobacillus and para-cheese, which is applied in the field of oral cleaning products, can solve the problems of paste water separation, large amount of addition, instability, etc., and achieve the effects of low production cost, good oral cavity, and stable system

Active Publication Date: 2018-07-27
SANJIAO ORAL HEALTH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the problems existing in the prior art (such as instability when probiotics are applied to toothpaste, large amount of addition, easy to cause problems such as water separation and yellowing of the paste), the inventor found through a large number of experiments that, in Under the condition that the pH value of the toothpaste system is 7.4-8.0, o-cymene-5-ol can effectively inhibit the influence of the metabolites in the inactivated Lactobacillus paracasei on the paste, and when used, it cooperates with Lactobacillus paracasei , effectively inhibit oral pathogenic bacteria, and bring about the oral care effect of preventing and alleviating dental caries, periodontal disease, etc.

Method used

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  • Toothpaste containing lactobacillus paracasei and preparation method of toothpaste

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1, the present invention contains the toothpaste of Lactobacillus paracasei and preparation thereof

[0030] Formula: xylitol 0.5kg, o-cymene-5-ol 0.05kg, sodium pyrophosphate 0.4kg, glycerin 10kg, hydroxymethylcellulose sodium 0.3kg, xanthan gum 1kg, sorbitol 50kg, silicon dioxide 5kg, 0.3kg of titanium dioxide, 15kg of calcium hydrogen phosphate dihydrate, 2kg of sodium lauryl sulfate, 0.5kg of Lactobacillus paracasei, 0.8kg of essence, and 100kg of water.

[0031] The toothpaste has a pH of 7.4.

[0032] Preparation:

[0033] S1. Take the prescribed amount of water and add it to the premixing pot A, then add the prescribed amount of xylitol and o-cymene-5-ol, stir until completely dissolved, and prepare the premixed liquid A for later use;

[0034] S2. Take the glycerin of the recipe amount and add it to the premixing pot B, then add the sodium pyrophosphate, sodium hydroxymethylcellulose and xanthan gum of the recipe amount, stir until completely dissol...

Embodiment 2

[0037] Embodiment 2, the present invention contains the toothpaste of Lactobacillus paracasei and preparation thereof

[0038] Formula: sodium saccharin 1kg, o-cymene-5-ol 0.1kg, sodium pyrophosphate 0.8kg, glycerin 15kg, sodium hydroxymethylcellulose 0.8kg, xanthan gum 0.5kg, sorbitol 35kg, silicon dioxide 10kg , 0.7kg of titanium dioxide, 10kg of calcium hydrogen phosphate dihydrate, 3kg of sodium lauryl sulfate, 1kg of Lactobacillus paracasei, 1.5kg of essence, and 100kg of water.

[0039] The toothpaste has a pH of 8.0.

[0040] Preparation:

[0041] S1. Take the prescribed amount of water and add it to the premixing pot A, then add the prescribed amount of sodium saccharin and o-cymene-5-ol, stir until completely dissolved, and prepare the premixed liquid A for later use;

[0042] S2. Take the glycerin of the recipe amount and add it to the premixing pot B, then add the sodium pyrophosphate, sodium hydroxymethylcellulose and xanthan gum of the recipe amount, stir until ...

Embodiment 3

[0045] Embodiment 3, the present invention contains the toothpaste of Lactobacillus paracasei and preparation thereof

[0046] Formula: xylitol 0.8kg, o-cymene-5-ol 0.07kg, sodium pyrophosphate 0.6kg, glycerin 12kg, hydroxymethylcellulose sodium 0.6kg, xanthan gum 0.6kg, sorbitol 45kg, dioxide 8kg of silicon, 0.5kg of titanium dioxide, 12kg of calcium hydrogen phosphate dihydrate, 2kg of sodium lauryl sulfate, 0.7kg of Lactobacillus paracasei, 1.2kg of essence, and 100kg of water.

[0047] The toothpaste has a pH of 7.8.

[0048] Preparation:

[0049] S1. Take the prescribed amount of water and add it to the premixing pot A, then add the prescribed amount of xylitol and o-cymene-5-ol, stir until completely dissolved, and prepare the premixed liquid A for later use;

[0050] S2. Take the glycerin of the recipe amount and add it to the premixing pot B, then add the sodium pyrophosphate, sodium hydroxymethylcellulose and xanthan gum of the recipe amount, stir until completely d...

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PUM

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Abstract

The invention belongs to the technical field of oral cavity cleaning articles, and particularly relates to toothpaste containing lactobacillus paracasei and a preparation method of the toothpaste. Thetoothpaste comprises 0.5-1% of a sweetening agent, 0.05-0.1% of o-cymene-5-ol, 0.4-0.8% of sodium pyrophosphate, 10-15% of glycerinum, 0.3-0.8% of carboxymethyl cellulose sodium, 0.5-1% of xanthan gum, 35-50% of sorbitol, 5-10% of silicon dioxide, 0.3-0.7% of a coloring agent, 10-15% of hydryoxyapetite, 2-3% of a surfactant, 0.5-1% of the lactobacillus paracasei, 0.8-1.5% of essence and the balance of water. The toothpaste is stable in formula system, can inhibit dental plaque, removes bad breath, can prevent and relieve oral cavity problems such as periodontitis and gingivitis, has an effectof freshening breath, and has a good oral cavity cleaning and nursing effect.

Description

technical field [0001] The invention belongs to the technical field of oral cleaning products, and in particular relates to a toothpaste containing Lactobacillus paracasei and a preparation method thereof. Background technique [0002] The human oral cavity is a complete ecosystem. The microorganisms that colonize the oral cavity include complex types of bacteria, fungi, mycoplasma, protozoa and viruses. Current studies have confirmed that there are as many as 700 known species of bacteria in the oral cavity. Between the microorganisms in the oral cavity, between the microorganisms and the oral tissue of the host, only by maintaining a good ecological balance can the oral cavity maintain a healthy state. If foreign microorganisms or other factors lead to a significant increase in the proportion of individual or several microorganisms inherent in the oral microecology and become the dominant bacteria in the colonization site, especially the increase in the proportion of path...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/34A61Q11/00A61P1/02A61P31/04
CPCA61K8/34A61K8/99A61K2800/592A61Q11/00
Inventor 林创有
Owner SANJIAO ORAL HEALTH CO LTD
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