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Gynecological anti-bacterial gel and production method thereof

A gel and gynecological technology, used in biochemical equipment and methods, topical antibacterial agents, pharmaceutical formulations, etc., can solve the problems of loss of antibacterial effect and loss of bactericidal effect of benzalkonium chloride, and achieve strong permeability and good addition. effect, high transparency effect

Inactive Publication Date: 2018-09-14
江苏万可瑞科技实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The pH value of the female vagina is 4.0, which is acidic. After pushing the antibacterial gel made of benzalkonium chloride and chlorhexidine into the vagina, the antibacterial effect will be rapidly reduced or lost. Moreover, women often use body wash or soap to clean For the perineum, these bath liquids and soaps are anionic surfactants, which are quickly neutralized after encountering cationic surfactants such as benzalkonium chloride and chlorhexidine, so that benzalkonium chloride, chlorhexidine, etc. lose their bactericidal effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] 1. To prepare 100 mL of gynecological antibacterial gel, the preparation steps are as follows:

[0031] 1. Take 0.1-10g of QM, moisten and disperse it with 5-10mL of glycerin or propylene glycol, stir gently until it becomes a uniform paste, then add 10-20 mL of purified water, stir evenly, and then use the concentration of 0.5-30% Sodium hydroxide aqueous solution or triethanolamine to adjust the pH value of the system to 4-4.5, after standing still for 48 hours, the system is fully expanded, and the QM glue is obtained.

[0032] 2. Take 0.1-10g of AVC, moisten and disperse it with 5-10mL of glycerin or propylene glycol, stir gently until it becomes a uniform paste, then add 5-10mL of purified water, stir well and let stand for 48 hours to make the system get Fully expand to obtain AVC glue.

[0033] 3. Take 0.1-10g of HPMC, moisten and disperse it with 5-10 mL of glycerol or propylene glycol, stir gently until it becomes a uniform paste, then add 10-20mL of purified wa...

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Abstract

The invention provides gynecological anti-bacterial gel and a production method thereof, and relates to the technical field of production of surgical dressing in the technical field of medical treatment and public health. A QM glue solution and an AVC glue solution are alternatively added into an HPMC glue solution, the mixture is stirred and mixed evenly to become gelatinous, not only are the specialties of various components exerted, but also a good addition effect is formed, so that the gel has the advantages that the gel is highly transparent, has low slumpability and good dispersity and permeability, effective components are quickly absorbed, and film is not formed easily, thereby avoiding the defects that film is formed when HPMC is separately used, and the effective components are not absorbed easily.

Description

technical field [0001] The invention relates to a medical dressing in the technical field of medical treatment and sanitation, in particular to the technical field of production of antibacterial gel used in gynecology. Background technique [0002] Various gynecological antibacterial gels have a great variety at present. According to market research, almost 100% of gynecological antibacterial gels are based on cellulose, especially hypromellose. Although this cellulose matrix has relatively good lubricity, it has significant film-forming properties. Therefore, a white film will be formed to cover the skin and mucous membranes during use, which will not only affect the air permeability and effectiveness of the skin and mucous membranes. The absorption of ingredients will also leave white debris and flaky white film-like things on the skin and mucous membranes, which will cause great distress and discomfort to users, so that many consumers who use this gel have to use it. To...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61K31/216A61K9/06A61K47/34A61K47/38A61K47/32A61P15/00A61P15/02A61P31/02
CPCA61K38/47A61K9/0034A61K9/06A61K31/216A61K47/32A61K47/34A61K47/38A61P15/00A61P15/02A61P31/02C12Y302/01017A61K2300/00
Inventor 孙廷柱
Owner 江苏万可瑞科技实业有限公司
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