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Composition and preparation for improvement of learning memory, and preparing method and application thereof

A technology of learning memory and composition, applied in application, drug combination, food science, etc., can solve the problem of no specific drugs and treatment methods for Alzheimer's disease, improve the degree of brain damage, inhibit the aggregation of Aβ protein, and improve learning and memory Effect

Active Publication Date: 2018-10-23
廖霭华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, medical research has shown that there are no specific drugs and treatments for Alzheimer's so far

Method used

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  • Composition and preparation for improvement of learning memory, and preparing method and application thereof
  • Composition and preparation for improvement of learning memory, and preparing method and application thereof
  • Composition and preparation for improvement of learning memory, and preparing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Preparation of Haematococcus Pluvialls Fat-Soluble Extract

[0027] Take 2kg of fresh Haematococcus pluvialis, put it in a high-pressure homogenizer to break the wall, collect the algae residue, and then use CO 2 Supercritical extraction for 4h, temperature 75°C, pressure 40MPa, CO 2 The flow rate was 25 L / h, and the fat-soluble extract was collected to obtain 550 g of the fat-soluble extract of Haematococcus pluvialis, wherein the astaxanthin content was 6%.

Embodiment 2

[0028] Embodiment 2 Ingot maple seed oil preparation

[0029] Take 4 kg of maple seed kernels, heat to 85-90 ° C, steam and fry for 40 minutes, and physically press with a 95-type screw oil press to obtain 1.4 kg of maple seed oil, of which the nervonic acid content is 6%.

Embodiment 3

[0030] Embodiment 3 composition soft capsule preparation

[0031] Capsule content prescription: composition 198g (including: curcumin 3g, Haematococcus pluvialis fat-soluble extract 30g, ingot maple seed oil 150g, celery seed oil 15g); excipient matrix 40g (including: polyethylene glycol 400, soybean lecithin).

[0032] Soft capsule preparation: (make 1000 capsules)

[0033] (1) Preparation of the contents of the capsule: Weigh each component according to the prescription amount of the contents, put them in a clean container, stir and mix for 30 minutes, put them in a colloid mill and grind them for 2 to 3 times, vacuumize and degas (vacuum degree -0.06~-0.08Mpa) ) discharge, let it stand for 2 hours, and observe that the mixture is transparent and free of bubbles, and the contents of the capsules are obtained.

[0034] (2) Sol: Weigh 200g of gelatin, 100g of glycerin, and 200g of water, put glycerin and water in a sol tank and heat to 40-50°C, put in gelatin and heat up to ...

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Abstract

The invention discloses a composition for remarkable improvement of learning memory, wherein the composition comprises curcumin, a haematococcus pluvialis lipid-soluble extract, acer truncatum seed oil and celery seed oil. The components of the formula have similar physical and chemical properties, different components and functions and different mechanisms of action, the technical effects of remarkable improvement of learning memory can be achieved through multi-target synergy, the composition has no toxic or side effect on human bodies, and can be widely used for preparing drugs and health-care products for improving leaning memory and preventing and treating senile dementia. The invention also provides soft capsules containing the composition and a preparing method thereof. The preparing method is simple and is suitable for industrialized production.

Description

technical field [0001] The invention relates to a composition and preparation for improving learning and memory. The preparation method and application thereof belong to the field of medicine and health care products. Background technique [0002] Learning and memory ability is an important and indispensable brain function for human beings to survive. The decline in learning and memory will seriously affect their ability to adapt to life and society, and greatly reduce their quality of life and sense of social presence. The decline or even degeneration of memory ability is closely related to the health status of the human body, physiological aging of the brain, brain trauma and pathological changes. In addition, the pressure brought about by the rapid economic and social development will also cause memory disorders in people of different age groups, thereby affecting normal life. According to data, about 5% to 15% of the elderly have different degrees of dementia symptoms, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61K9/48A61P25/28A23L33/115A23L33/135A23L33/105A23P10/30A61K31/12
CPCA23V2002/00A61K9/48A61K31/12A61K36/05A61K36/20A61K36/23A23L33/105A23L33/115A23L33/135A23P10/30A61P25/28A61K2300/00A23V2200/30A23V2250/2112A23V2250/202
Inventor 龙祥赵丽梅潘丽婷
Owner 廖霭华
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