4results about How to "Increase damage" patented technology

The invention discloses application of oridonin in preparation of an external preparation for treating skin scald, and belongs to the technical field of medicines. It is found for the first time that oridonin can effectively relieve the injury degree of skin scald and promote wound healing, the content of oridonin in the external preparation is 0.1-1% w / w, the dosage form can be selected from oil-in-water emulsion, plaster or hydrogel, and after the oridonin is matched with auxiliary materials such as a gel matrix and a transdermal enhancer, animal experiments prove that the oridonin can be used for preparing the external preparation. The 0.1% oridonin external preparation and the 1% oridonin external preparation can improve the symptoms of mice with scalded skin and promote wound healing, and the treatment effect of the oridonin external preparation is superior to that of asiaticoside ointment. According to the invention, the medicinal application of oridonin is expanded, a new effective medicine choice is provided for treating skin scald, and the oridonin has good clinical application value and popularization prospect.

The embodiment of the invention discloses a sterilization control method and device for refrigeration equipment and a storage medium, and belongs to the technical field of smart home. Comprising the steps of detecting the damage degree of food materials in the refrigeration equipment; and controlling the sterilization module to sterilize the food materials by adopting the sterilization intensity corresponding to the damage degree. According to the embodiment of the invention, by detecting the damage degree of the food material, the fresh state of the food material and the possible microbial contamination risk can be identified, so that the sterilization intensity of the sterilization module is automatically adjusted to adapt to different storage requirements of the food material, the sterilization effect is improved, and the energy consumption is reduced; the original flavor and nutritional value of the food materials can be kept, and the fresh-keeping period can be prolonged.

The present application provides the use of aucubin or the combination of aucubin and ACA in the preparation of a medicament for treating ischemic brain injury, in particular acute cerebral ischemia-reperfusion injury. The present application first discovers that aucubin or the combination of aucubin and ACA can increase the blood flow of the ischemic side after ischemic brain injury in mice; significantly reduce the cerebral infarction volume; improve the cognitive and motor function of mice after ischemic brain injury; reduce the degree of injury caused by cerebral ischemia, significantly improve the degree of neuronal necrosis of brain tissue after ischemia; significantly increase the survival rate of HT22 cells after oxygen-glucose deprivation and reperfusion injury, reduce intracellular Ca 2+ fluorescence intensity, and inhibit cell apoptosis.

The application provides an extraction method and application of antioxidant components in aronia melanocarpa fruits, and the extraction method comprises the following steps: (1) juicing and concentrating aronia melanocarpa to obtain aronia melanocarpa juice; (2) adding a composite enzyme into the aronia melanocarpa juice, and performing enzymolysis under ultrasonic waves; after the enzymolysis is completed, the aronia melanocarpa juice is extracted, filtered, and stratified by standing, the supernatant is collected, concentrated, and freeze-dried to obtain aronia melanocarpa crude extract; and (3) performing aqueous two-phase extraction on the aronia melanocarpa crude extract, centrifuging after filtration, concentrating and drying the supernatant to obtain the antioxidant components in the aronia melanocarpa fruits. The composite enzyme is used for enzymolysis, and ultrasonic waves are used for assistance, so that the antioxidant components in the aronia melanocarpa are released; and the aqueous two-phase extraction technology is further used, so that the antioxidant components in the aronia melanocarpa are effectively extracted. The antioxidant components in the aronia melanocarpa fruits extracted by the application can reach a hydroxyl radical clearance rate of 70.2% at a concentration of 3.2 mg / mL.