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Functional liquid dressing for hard-healing wounds and preparation method thereof

A liquid dressing and functional technology, applied in medical science, bandages, etc., can solve the problems of patients' ideological and economic burden, prolong hospital stay, increase patient pain, etc., reduce retrograde resistance and shear force, and increase the effect of inhibiting bacteria , The effect of removing the source of infection

Active Publication Date: 2018-12-11
海南一鸿实业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Including 1. Poor local blood supply: Wound repair requires rich blood supply, and insufficient tissue blood supply caused by various reasons will inevitably affect wound healing
2. Residual foreign matter: Foreign matter in the body will trigger the body's rejection reaction, making the wound tissue in the inflammatory reaction stage for a long time and affecting wound healing
[0007] The above factors are likely to increase the pain of patients and prolong the length of hospital stay, which will put a double burden on patients' thinking and economy.

Method used

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  • Functional liquid dressing for hard-healing wounds and preparation method thereof
  • Functional liquid dressing for hard-healing wounds and preparation method thereof
  • Functional liquid dressing for hard-healing wounds and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A functional liquid dressing for difficult-to-heal wounds, containing 0.26% solid raw materials by mass percentage, and the balance is water, wherein the solid raw materials include the following components: 10% organic silicon quaternary ammonium salt, Chitosan quaternary ammonium salt 85%, allantoin 1.8%, vitamin C 1.2%, calcium alginate (particle size: 10 μm) 2%, and the sum of each component of the solid raw material is 100%.

[0029] The preparation method of the described functional liquid dressing for difficult-to-heal wounds comprises the following steps:

[0030] 1) Dissolving the organosilicon quaternary ammonium salt in water to form a 3% organosilicon quaternary ammonium salt solution; after dissolving allantoin and vitamin C in water, adjust the pH to 5.0, and add calcium alginate to adjust the pH to 6.0;

[0031]2) Add water in the mixing tank, set the stirring speed of the mixer to 30 rpm, first add the chitosan quaternary ammonium salt, and make it compl...

Embodiment 2

[0034] A functional liquid dressing for difficult-to-heal wounds, characterized in that, by mass percentage, it contains 0.4% solid raw materials, and the balance is water, wherein the solid raw materials include the following components: organosilicon quaternary ammonium 75% of salt, 15% of chitosan quaternary ammonium salt, 1% of allantoin, 3% of vitamin C, 6% of calcium alginate (particle size is 80 μm), and the sum of each component of the solid material is 100%.

[0035] The preparation method of the described functional liquid dressing for difficult-to-heal wounds comprises the following steps:

[0036] 1) Dissolving the organosilicon quaternary ammonium salt in water to form a 3% organosilicon quaternary ammonium salt solution; after dissolving allantoin and vitamin C in water, adjust the pH to 5.0, and add calcium alginate to adjust the pH to 6.0;

[0037] 2) Add water in the mixing tank, set the stirring speed of the mixer to 30 rpm, first add the chitosan quaternary ...

Embodiment 3

[0040] A functional liquid dressing for difficult-to-heal wounds, containing 0.3% solid raw materials by mass percentage, and the balance is water, wherein the solid raw materials include the following components: 30% organic silicon quaternary ammonium salt, Chitosan quaternary ammonium salt 55%, allantoin 8%, vitamin C 3%, calcium alginate (70 μm in particle size) 4%, and the sum of each component of the solid raw material is 100%.

[0041] The preparation method of the described functional liquid dressing for difficult-to-heal wounds comprises the following steps:

[0042] 1) Dissolving the organosilicon quaternary ammonium salt in water to form a 3% organosilicon quaternary ammonium salt solution; after dissolving allantoin and vitamin C in water, adjust the pH to 5.0, and add calcium alginate to adjust the pH to 6.0;

[0043] 2) Add water in the mixing tank, set the stirring speed of the mixer to 30 rpm, first add the chitosan quaternary ammonium salt, and make it complet...

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Abstract

The invention provides a functional liquid dressing for hard-healing wounds. The functional liquid dressing is prepared from the following components of 10 to 175 of organosilicon quaternary ammoniumsalt, 15 to 85% of chitosan quaternary ammonium salt, 1 to 8% of allantoin, 1.2 to 3% of vitamin C, and 2 to 6% of calcium alginate, wherein the sum of the percentages of the solid raw materials is 100%. The functional liquid dressing has the advantages that the proportional ratio of the components is reasonable, the synergistic effect is realized, and the antibacterial, disinfection, bleeding-stopping, pain-relieving, anti-seepage, anti-sticking and healing-promoting functions are realized; the functions which cannot be realized by the traditional disinfection medicines and sanitary dressingscan be realized, and the obvious treatment effect is realized on the hard-healing wounds.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a functional liquid dressing for difficult-to-heal wounds and a preparation method thereof. Background technique [0002] Refractory wounds are also called refractory wounds and chronic wounds, but there is still a lack of a clear and unified definition. The International Society of Wound Healing defines it as a wound that cannot achieve complete anatomical and functional healing through a normal, orderly and timely repair process. Chronic non-healing wounds (ulcers) on the body surface refer to body surface wounds formed by various reasons, which fail to heal after more than 1 to 3 months (the time is not absolute) and have no tendency to heal. From the perspective of pathophysiology, the wounds that do not heal after a skin tissue defect cannot be repaired in a regular and orderly manner are called refractory wounds. Such patients are often secondary to other chroni...

Claims

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Application Information

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IPC IPC(8): A61L26/00
Inventor 王虹韵陈震
Owner 海南一鸿实业发展有限公司
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