Acellular dermal matrix-based hydrogel and preparation method thereof

An acellular dermis, hydrogel technology, applied in medical science, prosthesis and other directions, can solve problems such as affecting clinical use, increasing costs, environmental pollution, etc., and achieves the goal of supporting cell growth, reducing preparation costs, and low genetics. toxic effects
CN109821071AActive Publication Date: 2019-05-31上海仁康科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
上海仁康科技有限公司
Publication Date
2019-05-31

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Abstract

The invention discloses an acellular dermal matrix-based hydrogel and a preparation method thereof. The hydrogel uses an acellular dermal matrix as a raw material and crosslinks by using Ca2+ and EDC/NHS. The hydrogel has a porous structure, and the pores are communicated with each other. The hydrogel has a three-dimensional structure similar to human skin tissues, and enables the body tissue cells to grow rapidly. The hydrogel contains rich growth factors, has good biocompatibility and is more conducive to growth of supporting cells. The hydrogel has good shapeability, and can be prepared into different specifications according to needs. The hydrogel can not only be used for wound repair, but also is an excellent tissue engineered skin scaffold material, and can be used for the repair ofskin defects and preparation of tissue engineered skin.
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Claims

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