Visible and non-invasive diabetes diagnosis preparation as well as preparation and use methods thereof

Abstract

The invention relates to a visible and non-invasive diabetes diagnosis preparation as well as preparation and use methods thereof. The preparation comprises a solid preparation and a liquid preparation, wherein the solid preparation is a mixture of nano-Fe3O4 and TMB; the liquid preparation comprises an AuNCs solution and absolute ethyl alcohol. The invention also provides preparation and use methods of the preparation. During use, a mixture of nano-Fe3O4 and TMB is sucked by a magnetic brush to brush and show the dermal ridge of a sweat latent fingerprint sample, the surplus mixture is suckedaway by a magnetic brush, a spraying device is used for spraying the AuNCs solution towards fingerprints first, and then an anhydrous ethanol solution is sprayed after drying. The preparation and thepreparation and use methods thereof have the beneficial effects that the preparation is convenient to prepare, and has high sensitivity, good appearance effect, good stability and wide applicability;the preparation method is simple and easy to implement, easy to popularize and high in yield; the use method is not only convenient to operate, but also realizes visual and non-invasive effects, avoids blood drawing, alleviates pain of diabetic patients, and realizes real-time blood sugar self-test of diabetic patients.

Description

technical field [0001] The invention relates to the field of diabetes diagnosis and public security criminal technology fingerprint identification, in particular to a preparation for visual non-invasive diagnosis of diabetes and its preparation and use method. Background technique [0002] In recent years, people's living standards have been greatly improved, and people's living habits, environment and diet have also undergone great changes, resulting in an increase in the incidence of diabetes year by year. Diabetes mellitus (DM) is a metabolic disease caused by low insulin action or / and insufficient secretion, characterized by hyperglycemia. Long-term hyperglycemia in DM will damage multiple organs, leading to dysfunction and failure of multiple organs, especially heart, nerve, kidney, eye and vascular system lesions. DM is one of the diseases with high morbidity and mortality in the world at present. In developed countries, the incidence rate is 2% to 5%. In my country, ...

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Problems solved by technology

[0003] At present, many enzymatic methods are used for clinical determination of glucose, such as glucose oxidase method (GOD method), hexokinase method (HK method), glucose dehydrogenase method, etc., but because of the high specificity of the enzyme reagent, it is suitable for For example, the glucose oxidase method is easily interfered by reducing substances. For patients with high uric acid, the hexokinase method should be used.

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