A method for the modification of covalent organic framework materials

Abstract

The invention provides a method for modifying a covalent organic framework material, which comprises the following steps: 1) combining 1,3,5-tri-(4-aminophenyl)benzene and 2,5-dioxylmethyl-p-benzene Mix diformaldehyde, then add o-dichlorobenzene / n-butanol and acetic acid catalyst, go through multiple freezing-pumping-thawing cycles, then flame seal and heat, collect the precipitate by centrifugation, wash, Soxhlet extraction, dry, collect 2) Add 2-methyl-2-butene, sodium chlorite aqueous solution and glacial acetic acid to the dioxane suspension of TPB-DMTA-COF powder, and stir in the dark to obtain purple Solid; 3) Re-oxidize the purple solid in step 1) with an aqueous solution of sodium chlorite, separate by filtration, wash, and dry to obtain a purple powder. The preparation method of the method is simple, the synthesis conditions are easy to control, and the prepared O-TPB-DMTA-COF powder has a good glycopeptide enrichment effect.

Description

technical field [0001] The invention belongs to porous crystalline functional materials, and in particular relates to a modified method for constructing a covalent organic framework material with better glycopeptide enrichment. Background technique [0002] COFs are crystalline materials formed by organic building units linked by covalent bonds and regularly expanded. Compared with amorphous porous material phase, crystalline material has incomparable advantages. The crystalline porous material has a uniform pore structure and a narrow pore size distribution, and has potential applications in catalysis and material separation. Since the synthesis of COFs is a reversible reaction controlled by thermodynamics, the geometric structure, function and stereo orientation of the material can be precisely controlled, and its connection mode can be clarified. The structure of the obtained material can be predicted by the method, and the pore size can also be adjusted by changing the...

AI Technical Summary

Problems solved by technology

[0004] At present, the biggest challenge in the synthesis of COFs is the periodicity of the constructed functionalized COFs materials and the strength of the framework. While pursuing material stability and high specific surface area, it is still difficult to obtain highly crystalline and regular COFs materials.

Although the current research on COFs materials has made great progress, it is still in the initial stage. There are few domestic researches on this, and there are great limitations in its application.

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